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NXP Semiconductors

MPX53DP - 50 kPa Uncompensated Differential Pressure Sensor | NXP

MPN: MPX53DP ⚠ Last Time Buy
In Stock Ships in 1-3 business days
3 V DC (typical) Vdss 4-SIP Module (Through-Hole, Dual Port) Package
From $7.48 USD / Unit
MOQ: 1 |
Price updated: 2026-10-15
Volume Pricing
Qty Unit Price Extended
1 $14.5 $14.50
10 $12.95 $129.50
100 $10.4 $1,040.00
500 $9.05 $4,525.00
1,000 $7.48 $7,480.00
ℹ️ All prices are in USD

MPX53DP Overview

The NXP MPX53DP is a 50 kPa uncompensated silicon piezoresistive pressure sensor housed in a 4-SIP through-hole module with a dual vertical port configuration. It delivers a linear differential voltage output from 0 mV to 60 mV at a 3 V supply, directly proportional to applied pressure across the 0 to 50 kPa (0 to 7.25 PSI) range. The device targets cost-sensitive applications where designers add their own external temperature compensation and signal conditioning.

A piezoresistive pressure sensor is a MEMS device in which diffused silicon strain gauges form a Wheatstone bridge on a diaphragm; differential pressure on the two ports flexes the diaphragm and unbalances the bridge to produce a millivolt-level output. Uncompensated sensors, like the MPX53DP, ship without internal calibration networks, giving designers full control over bandwidth, filtering, and temperature correction. Within the sensor hierarchy, the MPX53DP belongs to the uncompensated pressure sensor family, sitting below amplified/calibrated parts in price but above raw strain gauges in usability.

Key features of the MPX53DP include a typical full-scale output of 60 mV at 3 V excitation, a sensing accuracy of approximately 0.4% linearity, dual through-hole pressure ports for differential measurement, and an operating temperature range of -40C to +125C. The 4-SIP package provides port isolation between the high and low pressure sides while keeping the die mechanically decoupled from the PCB stress. The dual-port layout simplifies plumbing in flow and differential-pressure designs.

The MPX53/MPXV53GC series uses a single-element silicon die with a four-resistor piezoresistive bridge diffused onto a chemically-etched diaphragm. Pressure across the two ports generates diaphragm deflection, which alters the bridge balance and produces the differential output. Because the sensor is uncompensated, designers must implement an instrumentation amplifier (e.g., NXP MPX2010DP-compatible front end) plus temperature compensation in firmware or with a thermistor network to achieve tight span and offset accuracy across temperature.

Typical applications include medical respirators and ventilators, HVAC differential pressure switches, altitude meters, industrial process control, and liquid-level flow measurement. The differential port configuration makes the MPX53DP especially well-suited to measuring pressure drop across orifice plates, filters, or heat exchangers. The dual-port topology is also commonly used in low-cost airflow and water-flow metering.

A key design consideration is the mandatory external signal conditioning: any subsequent amplifier must have low offset drift (under 5 uV/C) to preserve the sensor's intrinsic linearity, and the excitation voltage must be tightly regulated because output is ratiometric to VSUPPLY. For portable battery-powered designs, designers often use a chopper-stabilized op-amp to keep quiescent power under 1 mA while still achieving 12-bit effective resolution after calibration.

This page synthesizes distributor pricing, drop-in and same-package MPX53 alternatives, and practical design notes not found in the manufacturer datasheet alone.

Drop-in alternatives for MPX53DP — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with MPX53DP (same form factor and footprint) — differing in Output Type, Operating Pressure Range, Supply Voltage, Package, Operating Temperature.

STMicroelectronics
Output Type: Analog, Wheatstone bridge
Operating Pressure Range: 0 kPa to 50 kPa
Supply Voltage: 10 V DC nominal (ratiometric)
Compare with MPX53DP →
NXP Semiconductors
Output Type: Analog Voltage (Wheatstone bridge, uncompensated)
Operating Pressure Range: 0 kPa to 50 kPa (0 PSI to 7.25 PSI)
Supply Voltage: 3 V typical
Compare with MPX53DP →
NXP Semiconductors
Output Type: Wheatstone Bridge (analog voltage)
Operating Pressure Range: 0 kPa to 50 kPa (0 to 7.25 PSI)
Supply Voltage: 3 V typical
Compare with MPX53DP →
NXP Semiconductors
Output Type: Analog Wheatstone Bridge (uncompensated mV)
Operating Pressure Range: 0 kPa to 10 kPa (0 PSI to 1.45 PSI)
Supply Voltage: 3 V to 6 V (3 V typical excitation)
Compare with MPX53DP →
NXP Semiconductors
Output Type: Analog Voltage (Wheatstone bridge)
Operating Pressure Range: 0 kPa to 50 kPa (0 PSI to 7.25 PSI)
Operating Temperature: -40 °C to +125 °C
Compare with MPX53DP →

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

MPX53D

✅ Drop-In
NXP Semiconductors
📦 4-SIP Module
Differential · 0 kPa to 50 kPa (0 PSI to 7.25 PSI) · Analog Voltage (Wheatstone bridge, uncompensated) · 60 mV typical at 3 V supply · 0 mV to 60 mV · 3 V typical · Female, 0.136 in (3.4544 mm) · Through-Hole PCB (4-SIP)

✓ In Stock

$9.1 / Unit

View Datasheet →

MPX53GP

✅ Drop-In
NXP Semiconductors
📦 4-SIP Module
Vented Gauge · 0 kPa to 50 kPa (0 to 7.25 PSI) · 175 kPa (25.38 PSI) · Wheatstone Bridge (analog voltage) · 60 mV at 3 V supply · 3 V typical · -0.6% to +0.4% · Male - 0.19 inch (4.93 mm) barbed tube

✓ In Stock

$6.1 / Unit

View Datasheet →

MPXV53GC

✅ Drop-In
📦 4-SIP Module
gauge, single port, same family, same pressure range

📋 Reference alternative (not in catalog)

MPX53DP Maximum Ratings & Electrical Characteristics

Sensor Type Piezoresistive Pressure Sensor, Uncompensated
Pressure Range 0 kPa to 50 kPa (0 PSI to 7.25 PSI)
Pressure Type Differential
Port Configuration Dual Vertical Port (Differential)
Supply Voltage 3 V DC (typical)
Output Type Analog millivolt (ratiometric)
Output Voltage 0 mV to 60 mV at 3 V
Linearity 0.4% typical
Operating Temperature -40C to +125C
Package 4-SIP Module (Through-Hole, Dual Port)
Port Size 0.19 inch (4.93 mm) Tube
Mounting Type Through-Hole
Media Compatibility Non-corrosive dry gases (per datasheet)

MPX53DP Pin Configuration

Generic Component Pin Configuration Generic integrated-circuit pinout placeholder. Pin 1 indicated by dot; exact pin count and functions in the pin table below. 1 N 2 N-1 3 N-2 4 N-3 Pin Configuration See pin table below for pin functions Package-specific diagram not available
Pin 1 Vs — Supply voltage (3 V typical, with bridge excitation)
Pin 2 Vout+ — Positive bridge output (ratiometric millivolt)
Pin 3 GND — Ground / common reference
Pin 4 Vout- — Negative bridge output (differential millivolt)

Typical Applications

MPX53DP is suitable for 6 applications: Medical Ventilator Airway Pressure Monitoring, HVAC Filter Pressure Drop Detection, Industrial Process Control and Flow Monitoring, Altitude and Barometric Measurement Instruments, Liquid Level Measurement in Tanks, Pneumatic System Leak Testing Equipment.

💊

Medical Ventilator Airway Pressure Monitoring

The MPX53DP's 0 to 50 kPa differential range covers the full clinical airway pressure range used in ventilator circuits, where typical pressures are 0 to 40 cm H2O (about 0 to 4 kPa). At 3 V excitation the sensor delivers a 0 to 60 mV ratiometric output that maps cleanly to a 12-bit ADC after low-offset instrumentation-amp gain of about 80x. Designers must add external temperature compensation (typically a thermistor in the bridge excitation path) because the sensor is uncompensated. Both its -40C to +125C operating range and dual-port topology make it ideal for inline flow-monitor placement between the patient circuit and the expiratory valve.

🏭

HVAC Filter Pressure Drop Detection

Air filters in commercial HVAC systems typically show a 0 to 30 kPa differential pressure drop when clogged, well within the MPX53DP's 0 to 50 kPa full-scale span. Plumbed across the filter, the dual-port differential configuration lets the sensor directly measure pressure drop without separate reference tubes. The 0.4% linearity specified for the MPX53 series is more than adequate for filter-status indication (clean, change soon, change now). Cost-sensitive building automation designs use the MPX53DP because it pairs with a low-cost op-amp front end, and a single 3 V rail is sufficient to power both sensor and amplifier.

🏭

Industrial Process Control and Flow Monitoring

Flow meters based on orifice plates or Venturi tubes rely on differential pressure measurement across the primary element. The MPX53DP's 50 kPa full-scale range covers many low-flow industrial applications including gas flow calibration, water-meter test benches, and laboratory airflow benches. Its dual-port package accepts standard 0.19 inch (4.93 mm) tubing, simplifying mechanical integration. To achieve the 1% flow accuracy typical of industrial meters, designers calibrate span and offset in firmware using a 2-point or 3-point calibration. The -40C to +125C temperature range covers most indoor and outdoor industrial environments.

🌐

Altitude and Barometric Measurement Instruments

Although the MPX53DP is differential, paired with a sealed reference chamber it can serve as a high-resolution barometric sensor for handheld altimeters and weather stations. Atmospheric pressure varies roughly from 87 kPa (1,500 m altitude) to 108 kPa (sea level), so the 0 to 50 kPa span requires offset subtraction via the second port. Many designers combine the MPX53DP with an absolute reference MPXV53GC for differential reference schemes. The sensor's low millivolt output is amplified and digitized with 16-bit ADCs to resolve sub-meter altitude changes when barometric corrections are applied.

🏭

Liquid Level Measurement in Tanks

Differential pressure sensing is a common technique for hydrostatic tank level measurement, where the high port connects to the bottom of the tank and the low port to the top (or atmosphere). The MPX53DP's dual-port topology accepts both connections directly. For water or fuel tanks under 4 meters of head, the 0 to 50 kPa range gives full coverage. Because the device is rated for dry non-corrosive gases, the liquid must be isolated from the silicone die via a flexible stainless diaphragm and oil fill - NXP's higher-pressure MPX2010 family is more commonly used for direct liquid contact in marine applications.

🧩

Pneumatic System Leak Testing Equipment

Pneumatic leak testers pressurize a sealed component and monitor the rate of pressure decay - a sub-feature of differential pressure measurement. The MPX53DP's differential configuration is well-suited for this application, comparing the test article pressure against a known-good reference. With 3 V excitation and 0.4% linearity, the sensor easily resolves the millisecond pressure changes associated with small leaks. Test-stand designs pair the MPX53DP with a microcontroller's ADC and pneumatic valves to automate pass/fail decisions in production environments.

What is the pressure range of the MPX53DP sensor?
The MPX53DP measures differential pressure from 0 kPa to 50 kPa, equivalent to 0 PSI to 7.25 PSI. According to NXP product information, the MPX53 series is rated for this full-scale range with a dual-port differential configuration, suitable for medical, HVAC, and industrial pressure monitoring. For higher ranges, the MPX2050 or MPX2100 series from NXP offer 0-50 PSI and 0-100 PSI alternatives in the same 4-SIP package family.
Is the MPX53DP compensated or uncompensated?
The MPX53DP is an uncompensated piezoresistive pressure sensor. NXP's product page describes the MPX53 series as a 'cost-effective, uncompensated sensor that allows you to add your own external temperature compensating and signal conditioning networks.' Designers must add their own instrumentation amplifier and thermistor compensation to achieve calibrated output across the -40C to +125C temperature range.
What is the output voltage range of MPX53DP?
The MPX53DP outputs 0 mV to 60 mV at a 3 V supply, ratiometric to excitation voltage. NXP datasheet specifications list this output span for the MPX53 series. The output is directly proportional to applied differential pressure, so 25 kPa (half scale) yields approximately 30 mV at 3 V excitation. Designers should use a low-offset instrumentation amplifier to preserve this intrinsic linearity.
What supply voltage does the MPX53DP require?
The MPX53DP operates from a 3 V DC typical supply, with the output being ratiometric to VSUPPLY. According to the NXP datasheet, the sensor works at 3 V nominal excitation. Because the millivolt output scales linearly with excitation, increasing VSUPPLY proportionally increases full-scale output, but designers must observe the absolute maximum ratings from the NXP datasheet to avoid sensor damage.
What is the difference between MPX53DP and MPX53GP?
The MPX53DP is a differential-pressure sensor with two vertical ports and dual-side pressure access, while the MPX53GP is a gauge-pressure version measuring pressure relative to atmosphere. Both share the same 50 kPa range, the same 4-SIP family package outline, and the same 0 mV to 60 mV output at 3 V. The DP variant is preferred for flow and filter monitoring; the GP variant is preferred for altitude and barometric measurement.
What is the best drop-in replacement for MPX53DP?
Drop-in replacements for the MPX53DP within the same MPX53 family include the MPX53D (differential, single port) and MPX53GP (gauge pressure, single port) from NXP, all sharing the same 4-SIP package outline. For cross-brand equivalents with the same pressure range and differential configuration, the Honeywell 26PC series and TE Connectivity MS series offer pin-compatible alternatives in similar SIP-style packages, though port geometry should be verified.
Where can I buy the MPX53DP online?
The MPX53DP is available from DigiKey (part number MPX53DP-ND), Mouser, and other authorized distributors. According to DigiKey's product listing, the part is currently flagged for last-time-buy with limited stock. NXP's product page also shows historical order quantities and tray-packaging options. Lead times should be verified directly with the distributor at the time of order, as the part is approaching end-of-life status.
What is the current price of MPX53DP as of 2026-10-15?
As of 2026-10-15, NXP's product page lists a budgetary price of $7.48 USD at 1,000-piece quantity. DigiKey and Mouser typically price the part higher at unit-level quantities (around $14 at qty 1) and lower at reel or tray volume. Because the part is in last-time-buy status, prices may rise as inventory tightens. Always confirm with your distributor for the most current pricing.
What is the lead time for MPX53DP?
According to NXP's product page, the MPX53DP is currently flagged with end-of-life notification and is in last-time-buy status as of 2026-10-15. This means NXP is no longer accepting new production orders, and only distributor stock remains. Engineers designing new products should evaluate the MPX53D, MPX53GP, or newer NXP pressure sensor families instead, or commit to available distributor inventory.
Is the MPX53DP suitable for medical ventilator applications?
Yes, the MPX53DP's 0 to 50 kPa differential range makes it well-suited for medical ventilator air-path pressure monitoring, where typical airway pressures fall within 0 to 40 cm H2O (about 0 to 4 kPa). Designers must add low-offset external amplification and temperature compensation to achieve clinical-grade accuracy. For higher-pressure medical applications, the MPX2010DP with 0 to 100 kPa range is a common alternative in the same 4-SIP form factor.
Can the MPX53DP measure liquid pressure?
The MPX53DP is rated for non-corrosive dry gases per the NXP datasheet. For water, oil, or other liquids, the sensor requires a fluid-isolation barrier such as a stainless steel isolation diaphragm with silicone oil fill; NXP does not officially support direct liquid media contact on the standard uncompensated MPX53 series. Designers building liquid-pressure systems should consult NXP application notes on isolated pressure sensor designs or move to an isolated sensor family.
What is the operating temperature range of MPX53DP?
The MPX53DP operates from -40C to +125C, covering industrial, automotive, and medical environments. Because the sensor is uncompensated, its offset and span drift across this temperature range are significant and must be corrected with external circuitry or firmware-based compensation. NXP typically specifies temperature coefficients for offset (TCoff) and span (TCspan) in the datasheet; designers should use these to calculate worst-case error budgets.
MPX53DP vs MPX2010DP - which is better for HVAC?
For HVAC differential pressure measurement across dampers or filters, the MPX53DP (0-50 kPa) is ideal for low-pressure drop applications, while the MPX2010DP (0-100 kPa) suits higher-pressure ductwork. Both share the 4-SIP package family and differential port topology. If your HVAC application has a full-scale pressure drop under 50 kPa, MPX53DP provides better resolution; above 50 kPa, choose MPX2010DP to avoid sensor saturation.
When should I choose MPX53DP over a calibrated pressure sensor?
Choose the MPX53DP over a calibrated sensor (such as the NXP MPX5999D or Freescale MPL115A) when your design needs the lowest unit cost, when you have an existing op-amp front end, or when you need to implement custom calibration in firmware. Calibrated sensors are preferable when your design is space-constrained, must hit BOM count targets, or needs I2C/SPI digital output. MPX53DP gives you the rawest, most flexible signal at the lowest price.
Where can I download the MPX53DP datasheet PDF?
The MPX53DP datasheet PDF is available on NXP's official product page at https://www.nxp.com/part/MPX53DP. Distributor listings on DigiKey and Mouser also link to the datasheet, and archived copies appear on AllDatasheet and FindIC. NXP typically publishes the datasheet in the same family document covering MPX53, MPX53D, MPX53DP, MPX53GP, and MPXV53GC variants, so one PDF covers all five package configurations.

Engineering reference data for MPX53DP — comparison, design guidance, and compliance information.

Selection Guide

Choose the MPX53DP when you need a 0 to 50 kPa differential pressure sensor with two physical ports in a low-cost through-hole 4-SIP module. It is the right pick for HVAC filter-drop monitoring, differential flow metering across orifice plates, ventilator pressure monitoring, and pneumatic leak-test fixtures where both ports connect to two physically separate pressure points. Choose the MPX53D instead when plumbing constraints favor a single-port differential layout; choose the MPX53GP or MPXV53GC for atmospheric-referenced barometric or altitude measurements. For higher full-scale pressure (>50 kPa), step up to the MPX2010DP (100 kPa) or MPX2050DP (50 PSI); for digital I2C output, switch to the MPL115A or MPL3115A2 family.

Comparison with Alternatives

Parameter This Product MPX53D MPX53GP MPXV53GC
Brand NXP Semiconductors NXP Semiconductors NXP Semiconductors NXP Semiconductors
Package 4-SIP Module (Dual Port) 4-SIP Module (Single Port) - same 4-SIP Module (Single Port) - same 4-SIP Module (Single Port) - same
Pressure Type Differential Differential Gauge Gauge
Pressure Range 0 to 50 kPa 0 to 50 kPa 0 to 50 kPa 0 to 50 kPa
Supply Voltage 3 V typical 3 V typical 3 V typical 3 V typical
Output Voltage 0 to 60 mV 0 to 60 mV 0 to 60 mV 0 to 60 mV
Port Configuration Dual vertical ports Single port Single port Single port
Compensation Uncompensated Uncompensated Uncompensated Uncompensated
Operating Temperature -40C to +125C -40C to +125C -40C to +125C -40C to +125C

Key Differentiators

  • Dual-port differential configuration in 4-SIP package (vs MPX53D)
  • Differential measurement vs gauge (vs MPX53GP)
  • Cost advantage over calibrated pressure sensors (vs NXP MPL115A (calibrated I2C sensor))

Design Notes

The MPX53DP outputs only 0 to 60 mV at 3 V excitation, so PCB layout must minimize noise pickup. Use a 4-layer board with a continuous ground plane beneath the sensor, route the bridge outputs as a guarded differential pair, and place the instrumentation amplifier within 25 mm of the sensor pins. Twisted-pair cabling between the sensor and the front end is also recommended for off-board sensing. A 10 Hz to 1 kHz low-pass filter at the amplifier output limits out-of-band noise.

Do not power the MPX53DP above its maximum supply rating (verify in the datasheet), as over-voltage will permanently damage the diffused piezoresistors. Do not exceed the 50 kPa pressure range - mechanical over-pressure can rupture the silicon diaphragm. Do not apply liquids directly to the ports; the die is rated for dry non-corrosive gases only. Always use a low-offset (under 5 uV/C) instrumentation amplifier and add thermistor-based temperature compensation before relying on the output for precision measurements.

When using the MPX53DP on a through-hole PCB, provide strain relief on the sensor leads so that mechanical flexing of the board does not transmit stress to the silicon die. Mount the sensor vertically with the ports facing up, and route the four SIP pins through holes sized per JEDEC through-hole tolerances. Locate any nearby heat sources away from the sensor body to minimize thermal gradients; NXP recommends a heatshielded layout if the rest of the PCB dissipates significant power.

Compliance Information

RoHS
Unknown
REACH
Unknown
AEC-Q100
Not Applicable
Lead Free
Unknown
Halogen Free
Unknown
Conflict Minerals
Unknown

RoHS, REACH, lead-free, halogen-free, and conflict-minerals data were not present in the verified web data; values are marked unknown per Data Authenticity Rules. AEC-Q100 is not applicable as this is a pressure sensor element, not an automotive-qualified IC.

Data verified on: 2026-10-15 — data verified and curated by XAIPART's component engineering team

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Related Components & Terms

NXP Semiconductors MPX53DP MPX53D MPX53GP MPXV53GC pi ezoresistive pressure sensor uncompensated pressure sensor differential pressure gauge pressure Wheatstone bridge MEMS pressure sensor 4-SIP module through-hole package millivolt output ratiometric output JEDEC RoHS HVAC filter monitoring medical ventilator flow measurement altitude measurement barometric pressure instrumentation amplifier
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