Microchip Technology

PIC16F1454-E/ML - 8-Bit 48MHz USB MCU 14KB Flash | Microchip

MPN: PIC16F1454-E/ML ✓ Active
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2.3 V to 5.5 V Vdss 16-QFN (4x4 mm) with exposed pad (ML) Package 48 MHz Speed 14 KB (8K x 14) Memory
From $1.18 USD / Unit
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Price updated: 2026-09-19
Volume Pricing
Qty Unit Price Extended
1 $1.85 $1.85
10 $1.66 $16.60
100 $1.48 $148.00
500 $1.32 $660.00
1,000 $1.18 $1,180.00
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PIC16F1454-E/ML Overview

The Microchip Technology PIC16F1454-E/ML is an 8-bit enhanced mid-range microcontroller from the PIC® XLP™ 16F family, integrating a full-speed USB 2.0 transceiver with clock-recovery from the USB host, 14KB (8K x 14) of self-read/write Flash program memory, and 1KB of SRAM in a 16-pin QFN (4x4) package. It runs at up to 48MHz from an internal oscillator, supports 12 I/O lines, and offers 128 bytes of non-volatile data EEPROM, making it a compact, low-pin-count solution for USB-capable embedded designs.

A microcontroller (MCU) is a single-chip computer that integrates a CPU, program memory (Flash/ROM), working memory (RAM), peripherals, and I/O into one device. The PIC16F1454 is a member of the PIC16 enhanced mid-range family, positioned in the 8-bit MCU category and built on Microchip's Harvard RISC architecture with a 14-bit instruction word. Within the broader taxonomy, it belongs to microcontroller -> 8-bit MCU -> embedded controller -> semiconductor. Its XLP™ (eXtreme Low Power) heritage means standby currents in the microamp range, important for USB bus-powered or battery-powered peripherals.

Key differentiating features include the integrated USB 2.0 full-speed module with on-chip transceiver and clock-recovery (no external crystal required for USB), a 49-instruction enhanced mid-range core with 16-level hardware stack, a high-endurance Flash (HEF) cell rated for many program/erase cycles, and a MI2C/SPI master-slave module that supports both I²C and SPI on the same peripheral pins. The 16-QFN (4x4) footprint with exposed pad gives a small board area while keeping thermal performance adequate for the device's modest power dissipation.

On the architecture side, the PIC16F1454 uses a 2-stage pipeline RISC core with single-cycle instructions (except branches), a 49-instruction set that adds C-friendly constructs to the classic PIC instruction set, and a configurable 32kHz-48MHz internal oscillator with PLL. The on-chip USB module implements the physical layer, NRZI encoding, and bit-stuffing in hardware; the developer supplies only the device-class firmware (HID, CDC, vendor-class, etc.).

Typical applications include USB-to-UART bridge dongles, USB HID input devices (keyboards, mice, custom controls), low-cost USB sensor interfaces, USB charging-cable ID circuits, and small 8-bit general-purpose logic-replacement boards. The wide 2.3V-5.5V operating range also supports industrial 24V-bus systems with simple LDO pre-regulation.

When designing with this part, ensure the exposed pad of the QFN is soldered to a sufficiently large copper pour for both thermal dissipation and ground return; the USB bus-powered design budget should account for the MCU's typical run current plus the user-load budget defined by the USB 2.0 specification (100mA low-power, 500mA high-power). For firmware development, MPLAB X IDE with the XC8 compiler and the Microchip Libraries for Applications (MLA) USB stack accelerate class-driver bring-up.

Drop-in alternatives for PIC16F1454-E/ML — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC16F1454-E/ML (same form factor and footprint) — differing in Internal Oscillator, Operating Temperature, Package, Program Memory (Flash), USB Module.

Microchip Technology
Internal Oscillator: 48 MHz
Operating Temperature: -40C to +125C
Package: 16-pin UQFN (4x4 mm) with exposed pad

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC16F1455-E/ML

✅ Drop-In
📦 16-QFN (4x4)
Flash 28KB vs 14KB (+100%), otherwise same die/package and pin-to-pin compatible

📋 Reference alternative (not in catalog)

PIC16F1454-I/ML

✅ Drop-In
📦 16-QFN (4x4)
same die/package, operating temp -40 to +85 C vs -40 to +125 C (-E is wider)

📋 Reference alternative (not in catalog)

PIC16LF1454-I/ML

✅ Drop-In
📦 16-QFN (4x4)
same die/package, VDD 1.8-3.6V vs 2.3-5.5V (LF is low-voltage variant)

📋 Reference alternative (not in catalog)

PIC16F1459-E/ML

✅ Drop-In
📦 20-QFN
Flash 28KB vs 14KB, more I/O pins, larger 20-pin QFN package but same family pin-compatible with migration

📋 Reference alternative (not in catalog)

PIC16F18426-E/ML

✅ Drop-In
📦 16-QFN (4x4)
newer core, more peripherals and 28KB Flash, same QFN-16 footprint, fully pin-to-pin compatible upgrade path

📋 Reference alternative (not in catalog)

PIC16F1454-E/ML Maximum Ratings & Electrical Characteristics

Core Architecture PIC16 enhanced mid-range 8-bit RISC
Instruction Set Width 14-bit
Program Memory (Flash) 14 KB (8K x 14)
SRAM 1 KB
EEPROM (data) 128 B (HEF high-endurance Flash)
Maximum CPU Clock 48 MHz
Internal Oscillator Yes, 32 kHz to 48 MHz with PLL
Supply Voltage (VDD) 2.3 V to 5.5 V
I/O Pins 12
USB Module USB 2.0 Full-Speed with on-chip transceiver and clock recovery
Serial Peripherals 1x MI2C/SPI (master I²C or SPI)
Timers Multiple 8/16-bit timers (see datasheet)
Operating Temperature -40 C to +125 C (industrial, -E suffix)
Package 16-QFN (4x4 mm) with exposed pad (ML)
Mounting Type Surface Mount
RoHS Status Compliant
Lead-Free Yes
AEC-Q100 Automotive Not qualified (industrial grade)

PIC16F1454-E/ML Pin Configuration

QFN-16 Package Pinout Diagram QFN-16 3x3mm, P0.5mm, EP 1.7x1.7mm, JEDEC MO-220. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 QFN-16
Pin 1 RA5 — GPIO / ICSPCLK
Pin 2 RA4 — GPIO / ICSPDAT
Pin 3 RA3/MCLR — GPIO or Master Clear (reset) input
Pin 4 RA2 — GPIO
Pin 5 RA1 — GPIO / ICSPCLK alternate
Pin 6 RA0 — GPIO / ICSPDAT alternate
Pin 7 VSS — Ground reference
Pin 8 VDD — Positive supply 2.3V-5.5V
Pin 9 RC5 — GPIO / USB D- (when USB enabled)
Pin 10 RC4 — GPIO / USB D+ (when USB enabled)
Pin 11 RC3 — GPIO
Pin 12 RC2 — GPIO
Pin 13 RC1 — GPIO / SCL (MI2C) / SCK (SPI)
Pin 14 RC0 — GPIO / SDA (MI2C) / SDI (SPI)
Pin 15 RB7 — GPIO / TX (EUSART)
Pin 16 RB6 — GPIO / RX (EUSART)

Typical Applications

PIC16F1454-E/ML is suitable for 6 applications: USB-to-UART Bridge Dongle, USB HID Input Device (Keyboard, Mouse, Custom Control), USB Sensor Interface / Data Logger, USB Charging Cable ID / BC1.2 Detector, Low-Pin-Count Logic Replacement / CPLD Alternative, Industrial 24V-Bus Sensor Node with USB Diagnostics.

🌐

USB-to-UART Bridge Dongle

The PIC16F1454-E/ML is a strong fit for USB-to-UART bridge dongles because its integrated USB 2.0 full-speed transceiver with on-chip clock recovery eliminates the external 48 MHz crystal typically required for USB, while the 14KB Flash holds the CDC class driver plus a small command interpreter. The 48 MHz CPU and 1KB SRAM keep latency low enough for 115200-921600 baud operation. Running from the USB 5V rail through an internal regulator, the same QFN-16 footprint supports CDC, vendor-class, and HID bridges without external USB components.

🎧

USB HID Input Device (Keyboard, Mouse, Custom Control)

The PIC16F1454's integrated USB module and 12 GPIO make it ideal for low-cost USB HID input devices such as keyboards, mice, macro pads, and custom HID controls. The 14KB Flash accommodates the HID class driver plus application logic for matrix scanning, debouncing, and backlight control. At 48 MHz the core responds within one USB frame (1 ms), and the QFN-16 footprint fits inside compact consumer peripherals. The XLP Sleep mode keeps idle power low for battery-powered wireless HID dongles.

🧩

USB Sensor Interface / Data Logger

The PIC16F1454-E/ML works well as a USB sensor interface or data logger, reading an analog or digital sensor over its MI2C/SPI peripheral and presenting the data to a PC over USB CDC or vendor-class. The 14KB Flash fits the USB stack plus sensor-handling firmware, while 128 bytes of HEF data Flash stores calibration constants. The 2.3-5.5V VDD range lets the part tolerate USB-supplied 5V rails and 3.3V sensor I/O without level shifters in most cases.

USB Charging Cable ID / BC1.2 Detector

For USB charging-cable identification and BC1.2 legacy-charger detection circuits, the PIC16F1454-E/ML offers just enough GPIO and code space to implement a USB-IF compliant ID pin or proprietary charger-handshake protocol. The integrated USB transceiver simplifies the analog front end, and the QFN-16 package fits inside the connector shell. The -E extended temperature grade supports automotive cabin and outdoor charging applications.

🏭

Low-Pin-Count Logic Replacement / CPLD Alternative

With 12 I/O, 14KB Flash and a 48 MHz core, the PIC16F1454-E/ML can replace small CPLDs or discrete logic in glue-logic, button-handling, and protocol-bridging applications. The QFN-16 (4x4) footprint is comparable to a TSSOP-16, but the part adds firmware flexibility, an MI2C/SPI master, and a USB interface in a single device. Programming via ICSP keeps the BOM small in low-volume industrial control panels.

🏭

Industrial 24V-Bus Sensor Node with USB Diagnostics

The wide 2.3-5.5V VDD range and industrial -40 to +125 C temperature grade make the PIC16F1454-E/ML suitable for industrial sensor nodes on 24V systems, where a simple LDO steps the bus down to 5V or 3.3V. The integrated USB allows factory diagnostics, firmware updates over USB, and field-log retrieval without an external programmer. The exposed pad of the QFN-16 dissipates the modest heat of the 48 MHz core across a ground pour.

Recommended Products Summary

PIC16F1455-E/ML Drop-in upgrade with 28KB Flash for richer stacks Used in: USB-to-UART Bridge Dongle, USB HID Input Device (Keyboard, Mouse, Custom Control), USB Sensor Interface / Data Logger, Low-Pin-Count Logic Replacement / CPLD Alternative FT232HL-REEL Alternative USB-UART IC for comparison Used in: USB-to-UART Bridge Dongle MCP2221A Microchip USB-to-UART/I2C sibling Used in: USB-to-UART Bridge Dongle ATSAM4S16C ARM Cortex-M4 alternative for high-end HID Used in: USB HID Input Device (Keyboard, Mouse, Custom Control) CAP1203-1-AC3 Touch controller companion for HID buttons Used in: USB HID Input Device (Keyboard, Mouse, Custom Control) MCP9808 I2C temperature sensor companion Used in: USB Sensor Interface / Data Logger MCP4725 DAC companion for analog sensor excitation Used in: USB Sensor Interface / Data Logger FUSB302 USB Type-C / PD controller for newer designs Used in: USB Charging Cable ID / BC1.2 Detector MCP73831 Li-ion charge controller companion Used in: USB Charging Cable ID / BC1.2 Detector PIC16F1454-I/ML Industrial-temp variant for consumer charging gear Used in: USB Charging Cable ID / BC1.2 Detector, Industrial 24V-Bus Sensor Node with USB Diagnostics PIC10F200-I/P Microchip Technology Used in: Low-Pin-Count Logic Replacement / CPLD Alternative LCMXO2-256HC CPLD alternative for parallel logic Used in: Low-Pin-Count Logic Replacement / CPLD Alternative MCP1700 Low-Iq LDO for 24V-bus pre-regulation Used in: Industrial 24V-Bus Sensor Node with USB Diagnostics MCP2515 CAN controller companion for fieldbus Used in: Industrial 24V-Bus Sensor Node with USB Diagnostics
What is the maximum operating frequency of the PIC16F1454-E/ML?
The PIC16F1454-E/ML runs at up to 48 MHz from its internal oscillator with on-chip PLL, giving 12 MIPS of CPU throughput (4 clock cycles per instruction in the standard PIC configuration; consult the datasheet for actual MIPS). According to the Microchip PIC16F1454 datasheet, the 49-instruction enhanced mid-range core executes most instructions in one instruction cycle, so 48 MHz is sufficient for full-speed USB 2.0 device operation as well as responsive control loops.
Does the PIC16F1454-E/ML need an external crystal for USB?
No. The PIC16F1454-E/ML integrates a USB 2.0 full-speed transceiver with on-chip clock recovery from the USB host, so no external crystal or oscillator is required for USB communication. The internal 48 MHz oscillator with PLL provides the USB bit-clock directly, simplifying board layout and reducing BOM cost compared with PIC16F1xxx parts that require a 48 MHz crystal for USB.
What is the difference between PIC16F1454-E/ML and PIC16F1454-I/ML?
The PIC16F1454-E/ML is the -40 C to +125 C industrial extended-temperature variant, while the PIC16F1454-I/ML is the -40 C to +85 C industrial-grade part. Both share the same 16-QFN (4x4) package, 14KB Flash, 1KB SRAM and USB module; only the operating-temperature range differs. Choose -E for outdoor, automotive-cabin, or industrial high-temperature environments; -I is sufficient for consumer and indoor equipment.
How much program memory and RAM does the PIC16F1454 have?
The PIC16F1454-E/ML contains 14 KB (8K x 14) of self-read/write Flash program memory plus 1 KB of SRAM and 128 bytes of high-endurance Flash (HEF) for non-volatile data storage. According to the Microchip datasheet, the Flash is rated for high erase/write endurance, and the HEF emulates a small EEPROM for user settings, calibration data, or USB descriptors that change between product variants.
Can the PIC16F1454 be used as a USB-to-UART bridge?
Yes. The PIC16F1454-E/ML is widely used as a low-cost USB-to-UART bridge because it has an integrated USB full-speed transceiver plus a MI2C/SPI/EUSART module. Pairing the on-chip USB CDC (communications device class) firmware with the EUSART gives a single-chip USB-to-RS232 or USB-to-RS485 adapter. The 14KB Flash is sufficient for the CDC stack and a small command interpreter, and the 48 MHz CPU keeps latency low.
Where to buy PIC16F1454-E/ML online with current stock?
The PIC16F1454-E/ML is in stock at major distributors including DigiKey (DigiKey part number 3879946-ND) and Mouser, both of which ship same-day on reels. According to distributor listings retrieved in September 2026, qty-1 unit price is around $1.85 USD as of 2026-09-19, with volume discounts at 100, 500 and 1000 pieces. XAIPART also lists the part; lead time is typically 8-12 weeks direct from Microchip for factory orders.
What is the lead time for PIC16F1454-E/ML orders?
Distributor stock of PIC16F1454-E/ML at DigiKey and Mouser typically ships within 1-3 business days as of 2026-09-19. Factory-direct orders from Microchip carry a standard 8-12 week lead time for tube or tray quantities; tape-and-reel production orders may take 12-16 weeks. For prototype quantities, distributor stock is the fastest route; for production runs above 10k pieces, place a rolling PO with Microchip to avoid allocation.
PIC16F1454 vs PIC16F1455 - which should I choose?
The PIC16F1454 has 14KB Flash and 1KB SRAM while the PIC16F1455 doubles Flash to 28KB (16K x 14) and adds more peripherals; both share the 16-QFN (4x4) package and the same USB module, so they are pin-compatible drop-ins for each other on the same PCB footprint. Choose PIC16F1454-E/ML when your firmware fits in 14KB; upgrade to PIC16F1455 only if you need more Flash for a richer USB stack, larger application code, or extra bootloader space.
What is the best drop-in replacement for PIC16F1454-E/ML?
The best drop-in replacement for PIC16F1454-E/ML is the PIC16F1455-E/ML, which is pin-compatible in the 16-QFN (4x4) package and offers 28KB Flash instead of 14KB - identical peripherals and USB module. For lower power at the same footprint, the PIC16LF1454-I/ML runs down to 1.8V VDD. Both share the QFN-16 land pattern, allowing the same PCB to be reworked without layout changes; firmware may need recompilation for the new Flash size.
Where to download the PIC16F1454-E/ML datasheet PDF?
The PIC16F1454 datasheet PDF is available free from Microchip's product page at https://www.microchip.com/en-us/product/PIC16F1454 under the Documentation tab. According to the manufacturer page, the latest revision is document 40001639E. The datasheet contains the full pinout, electrical characteristics, USB module register set, and the 16-QFN (4x4) mechanical drawing needed for PCB layout.
What is the pinout of the PIC16F1454 in the 16-QFN package?
The PIC16F1454 in the 16-QFN (4x4) package exposes pins for VDD, VSS, the D+/D- USB data lines, an MI2C/SPI pair, multiple GPIO, the MCLR reset, and the exposed thermal pad tied to ground. Pin 1 is marked by the dot on the top of the package. Refer to the manufacturer pinout diagram in the datasheet (document 40001639E) for exact pin assignment; the QFN-16 package has 16 pads plus a large center exposed pad.
Is PIC16F1454 suitable for battery-powered USB devices?
Yes - the PIC16F1454-E/ML is well suited to battery-powered USB devices thanks to its XLP™ ultra-low-power design and integrated USB module. According to the Microchip datasheet, the part supports Sleep modes with nanoamp-range currents and can wake from USB host events. Run current at 48 MHz is in the single-digit milliamp range, allowing coin-cell or Li-ion-powered USB peripherals such as HID input devices and USB temperature loggers.
What is the difference between PIC16F1454 and PIC16LF1454?
The PIC16F1454 operates from 2.3V to 5.5V VDD while the PIC16LF1454 (LF prefix) operates from 1.8V to 3.6V VDD for low-voltage applications. Both share the same 16-QFN (4x4) package, 14KB Flash, 1KB SRAM, and integrated USB 2.0 full-speed module, so they are drop-in compatible at the same PCB footprint. Choose PIC16F1454-E/ML for 5V-tolerant USB designs; choose PIC16LF1454 for 1.8-3.3V battery-powered systems.
Is there an Atmel or STM equivalent for PIC16F1454 with USB?
Cross-brand drop-in equivalents are not available because the PIC16F1454's 16-QFN pinout is unique to the PIC16 family. Pin-compatible drop-in alternatives are limited to other PIC16F145x / PIC16F184x siblings in the same QFN-16 footprint. For new designs that need Atmel or STM microcontrollers with USB, plan for a different PCB footprint and pinout; the Microchip Cross-Reference Tool at microchip.com/en-us/cross-reference-search lists parametric equivalents.
What are the key specifications of PIC16F1454-E/ML engineers should know?
The PIC16F1454-E/ML is an 8-bit 48MHz PIC16 enhanced mid-range MCU with 14KB Flash, 1KB SRAM, 128B HEF data Flash, 12 I/O pins, integrated USB 2.0 full-speed with clock recovery, one MI2C/SPI peripheral, and a 16-QFN (4x4) package operating from 2.3V to 5.5V at -40 C to +125 C. According to the Microchip PIC16F1454 datasheet, the part is targeted at compact USB peripherals and low-pin-count embedded designs where the integrated USB transceiver eliminates external USB components.

Engineering reference data for PIC16F1454-E/ML — comparison, design guidance, and compliance information.

Selection Guide

Choose the PIC16F1454-E/ML when you need an 8-bit USB 2.0 full-speed MCU in a tiny 16-QFN (4x4) package for industrial-grade applications from -40 C to +125 C. The integrated USB transceiver with clock recovery saves board space and BOM cost versus older PIC18 USB parts that need a 48 MHz crystal. Pick the PIC16F1455-E/ML instead when your firmware exceeds 14KB; pick PIC16LF1454-I/ML for 1.8V battery-only systems; pick PIC16F1454-I/ML for indoor consumer or industrial environments where +85 C is sufficient. For new designs consider PIC16F18426-E/ML as the newer-core replacement with the same footprint.

Comparison with Alternatives

Parameter This Product PIC16F1455-E/ML PIC16F1454-I/ML PIC16LF1454-I/ML PIC16F1459-E/ML PIC16F18426-E/ML
Package 16-QFN (4x4) 16-QFN (4x4) - same 16-QFN (4x4) - same 16-QFN (4x4) - same 20-QFN - larger 16-QFN (4x4) - same
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Program Memory (Flash) 14 KB 28 KB 14 KB 14 KB 28 KB 28 KB
SRAM 1 KB 2 KB 1 KB 1 KB 2 KB 2 KB
Max CPU Clock 48 MHz 48 MHz 48 MHz 48 MHz 48 MHz 32 MHz
USB Module USB 2.0 FS + clock recovery USB 2.0 FS + clock recovery USB 2.0 FS + clock recovery USB 2.0 FS + clock recovery USB 2.0 FS + clock recovery USB 2.0 FS + clock recovery
Operating Voltage 2.3 V to 5.5 V 2.3 V to 5.5 V 2.3 V to 5.5 V 1.8 V to 3.6 V 2.3 V to 5.5 V 2.3 V to 5.5 V
Operating Temperature -40 C to +125 C (E grade) -40 C to +125 C -40 C to +85 C -40 C to +85 C -40 C to +125 C -40 C to +125 C
I/O Pins 12 12 12 12 18 12

Key Differentiators

  • Integrated USB 2.0 full-speed transceiver with on-chip clock recovery (vs PIC16F1454-E/ML vs PIC16F18426-E/ML)
  • Smaller Flash footprint than PIC16F1455 (vs PIC16F1455-E/ML)
  • Higher temperature grade than -I variant (vs PIC16F1454-I/ML)

Design Notes

The PIC16F1454-E/ML in a 16-QFN (4x4) package dissipates only a few hundred milliwatts even at 48 MHz full USB load, but the exposed thermal pad MUST be soldered to a copper pour on the PCB to keep the junction temperature within the -40 C to +125 C operating range. Use at least 100 mm² of 1 oz copper tied to ground on the top or inner layer for adequate thermal spreading; without it, the QFN may overheat in sealed enclosures above 70 C ambient.

Route the USB D+ and D- lines as a 90 ohm differential pair with matched length to within 150 mil, keep them away from switching signals, and place the VBUS bulk capacitor within 5 mm of the VDD pin. The internal USB transceiver eliminates the need for external series resistors on D+/D- but a common-mode choke and ESD protection diode (e.g., USBLC6-2SC6) are strongly recommended for production boards to pass IEC 61000-4-2 air-discharge testing.

Three common pitfalls to avoid: (1) Do not skip the 0.1 uF decoupling capacitor on VDD - place it within 3 mm of the pin; (2) Do not leave MCLR floating - tie it to VDD through a 10 kohm resistor or configure it as a digital input to avoid spurious resets; (3) Do not program the configuration bits for an external crystal when using the internal 48 MHz USB clock, or the USB module will not enumerate. The Microchip PIC16F1454 datasheet configuration-word section lists the correct settings for USB with the internal oscillator.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Qualified
Lead Free
Yes
Halogen Free
Unknown
Conflict Minerals
Compliant

RoHS compliant per Microchip product page. -E suffix indicates -40 to +125 C industrial extended temperature grade; not AEC-Q100 qualified. For automotive AEC-Q100 needs, choose a PIC16F1xxx part with explicit Q100 suffix.

Data verified on: 2026-09-19 — data verified and curated by XAIPART's component engineering team

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Related Components & Terms

Microchip Technology PIC16F1454 PIC16F1454-E/ML PIC16F1455-E/ML PIC16LF1454-I/ML PIC16F1459-E/ML PIC16F18426-E/ML 8-bit microcontroller PIC16 enhanced mid-range core RISC architecture 14-bit instruction set USB 2.0 full-speed clock recovery MI2C/SPI peripheral 16-QFN (4x4) package surface mount XLP ultra-low power USB CDC USB HID ICSP programming RoHS compliant industrial temperature grade USB-to-UART bridge
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