Microchip Technology

PIC18F44K22-E/ML - 8-bit MCU, 16KB Flash, 44-QFN | Microchip

MPN: PIC18F44K22-E/ML ✓ Active
In Stock Ships in 1-3 business days
4.2 V to 5.5 V (E-temperature variant) Vdss 44-pin QFN (8x8 mm), exposed pad (ML) Package 48 MHz Speed 16 KB Flash Memory
From $2.84 USD / Unit
MOQ: 1 |
Price updated: 2026-09-27
Volume Pricing
Qty Unit Price Extended
1 $4.16 $4.16
10 $3.92 $39.20
100 $3.59 $359.00
500 $3.2 $1,600.00
1,000 $2.84 $2,840.00
ℹ️ All prices are in USD

PIC18F44K22-E/ML Overview

The Microchip Technology PIC18F44K22-E/ML is an 8-bit PIC18 microcontroller built on the enhanced RISC architecture, offering up to 48 MHz operation with 16KB Flash program memory, 768 bytes of SRAM, and 256 bytes of EEPROM. It is housed in a 44-pin QFN (8x8 mm) surface-mount package with an exposed pad for enhanced thermal dissipation. The 'E' suffix indicates the Extended (automotive-grade) temperature range of -40C to +125C, while the 'ML' suffix indicates the QFN package variant.

A microcontroller (MCU) is a single-chip computer containing a CPU, volatile and non-volatile memory, programmable I/O, and on-chip peripherals. The PIC18F family is Microchip's mainstream 8-bit line, positioned between the lower-end PIC16F and the more highly integrated PIC24/dsPIC families. It targets cost-sensitive embedded control, sensor interfacing, and human-machine interface (HMI) applications. The PIC18F44K22 specifically belongs to the 'K22' sub-family that adds nanoWatt XLP extreme-low-power technology, integrated capacitive touch (mTouch) peripherals, and automotive AEC-Q100 qualification, making it suitable for AEC-Q100 applications.

Key features include 36 I/O pins arranged across 5 ports (PORTA-PORTE), a 10-bit ADC with up to 28 channels, two analog comparators, three enhanced USART modules, two I2C/SPI capable MSSP modules, and two 8-bit timers combined with three 16-bit timers. The nanoWatt XLP technology delivers extremely low sleep currents suitable for battery-powered applications. The 44-QFN package with exposed pad provides a compact 8x8 mm footprint while maintaining excellent thermal performance.

Typical applications include HVAC fan controllers, automotive body and interior modules, white goods and small appliances, USB device controllers using the integrated USB 2.0 full-speed peripheral, and general purpose sensor/actuator nodes. The wide operating voltage range of 1.8V to 5.5V (with 4.2V-5.5V for the variant specified) allows direct connection to 5V sensors and 3.3V digital logic. This page synthesizes distributor pricing, drop-in alternatives, and practical design notes not typically consolidated in the manufacturer datasheet.

Drop-in alternatives for PIC18F44K22-E/ML — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC18F44K22-E/ML (same form factor and footprint) — differing in Package, MSL Level, Operating Temperature, Timers, Core Architecture.

Microchip Technology
Package: 44-pin QFN (8x8 mm) with Exposed Pad (ML)
MSL Level: MSL3 (per typical QFN moisture sensitivity)
Microchip Technology
Package: 44-pin QFN-EP (ML), exposed pad
MSL Level: 3 (per family datasheet)
Operating Temperature: -40C to +85C (industrial, 'I' suffix)
Microchip Technology
Package: 44-pin QFN (ML) 8x8 mm with exposed pad
Operating Temperature: -40C to +85C (Industrial, I grade)
Timers: 8-/16-bit, multiple CCP/ECCP
Microchip Technology
Package: QFN-44 (8x8 mm) - ML
MSL Level: 1 (unlimited)
Operating Temperature: -40C to +125C (Industrial)

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC18F44K22-I/ML

✅ Drop-In
Microchip Technology
📦 44-QFN (8x8)
8-bit PIC18 RISC · PIC18 (16-bit instructions, 8-bit data path) · 64 MHz (16 MIPS) · 16 KB (8K x 16) · 768 B · 256 B · 1.8 V to 5.5 V (2.3 V min for 64 MHz; 4.2 V-5.5 V per DigiKey entry) · 36

✓ In Stock

$2.1 / Unit

View Datasheet →

PIC18F45K22-I/ML

✅ Drop-In
Microchip Technology
📦 44-QFN (8x8)
PIC 8-bit RISC · 32 KB Flash (16K x 16) · 1536 B · 256 B · 64 MHz (16 MIPS) · 2.3 V to 5.5 V (1.8 V with regulator disabled) · 36 · 12-bit, up to 30 channels

✓ In Stock

$2.65 / Unit

View Datasheet →

PIC18F46K22-I/ML

✅ Drop-In ⚠️ Specs Unverified
Microchip Technology
📦 44-QFN (8x8)
PIC18F XLP · 8-bit PIC RISC · 64 KB · 3968 B · 1024 B · 64 MHz · 16 MIPS · 2.5 V to 5.5 V

✓ In Stock

$3.08 / Unit

View Datasheet →

PIC18F44K22T-I/ML

✅ Drop-In
Microchip Technology
📦 44-QFN (8x8)
PIC18 Enhanced 8-bit RISC · 16 KB (8K x 16 words) · 64 MHz · 16 MIPS · 2.5V / 3.3V / 5V nominal; 1.8V to 5.5V extended · 36

✓ In Stock

$2.05 / Unit

View Datasheet →

PIC18F43K22-I/ML

✅ Drop-In ⚠️ Specs Unverified
Microchip Technology
📦 44-QFN (8x8)
8-bit PIC18 RISC (Harvard) · PIC18 enhanced 8-bit · 8 KB (4K x 16) · 3968 bytes · 256 bytes · 64 MHz (16 MIPS) · 2.5 V / 3.3 V / 5 V · -40 C to +85 C (Industrial)

✓ In Stock

$1.95 / Unit

View Datasheet →

PIC18F44K22-E/ML Maximum Ratings & Electrical Characteristics

Product Family PIC18F K22
Core Architecture 8-bit PIC18 RISC (enhanced)
CPU Frequency (max) 48 MHz
Program Memory 16 KB Flash
SRAM 768 bytes
EEPROM 256 bytes
Number of I/O Pins 36
ADC 10-bit, up to 28 channels
Supply Voltage 4.2 V to 5.5 V (E-temperature variant)
Operating Temperature -40C to +125C (Extended, 'E')
Package 44-pin QFN (8x8 mm), exposed pad (ML)
Mounting Type Surface Mount
MSL Level 1 (per JEDEC J-STD-020)
Timers 3 x 16-bit + 2 x 8-bit
Communication Interfaces 3x EUSART, 2x MSSP (I2C/SPI)
Automotive Qualification AEC-Q100 qualified (E-suffix variant)
RoHS Status Compliant
Low-Power Technology nanoWatt XLP
Instruction Set PIC18 enhanced
Programmable Output Yes (memory-mapped peripherals)

PIC18F44K22-E/ML Pin Configuration

Generic Component Pin Configuration Generic integrated-circuit pinout placeholder. Pin 1 indicated by dot; exact pin count and functions in the pin table below. 1 N 2 N-1 3 N-2 4 N-3 Pin Configuration See pin table below for pin functions Package-specific diagram not available
Pin 1 MCLR/RE3 — Master Clear reset input / PORTE bit 3
Pin 2 RA0/AN0/C1IN0-/ULPWU — PORTA bit 0 / Analog input 0 / Comparator input
Pin 3 RA1/AN1/C1IN1-/C2IN1- — PORTA bit 1 / Analog input 1 / Comparator inputs
Pin 4 RA2/AN2/C1IN2-/C2IN2-/VREF- — PORTA bit 2 / Analog input 2 / VREF- reference
Pin 5 RA3/AN3/C1IN3+/VREF+ — PORTA bit 3 / Analog input 3 / VREF+ reference
Pin 6 RA4/T0CKI/C1OUT — PORTA bit 4 / TMR0 clock / Comparator 1 output
Pin 7 RA5/AN4/C2OUT/VDD — PORTA bit 5 / Analog input 4 / 2nd comparator output / alternative VDD
Pin 8 RE0/AN5 — PORTE bit 0 / Analog input 5
Pin 9 RE1/AN6 — PORTE bit 1 / Analog input 6
Pin 10 RE2/AN7 — PORTE bit 2 / Analog input 7
Pin 11 VDD — Positive supply voltage
Pin 12 VSS — Ground reference
Pin 13 OSC1/RA7 — Crystal oscillator input / PORTA bit 7 alt
Pin 14 OSC2/RA6 — Crystal oscillator output / PORTA bit 6 alt
Pin 15 RC0/SOSC1/SCK1 — PORTC bit 0 / Secondary osc / SPI1 clock
Pin 16 RC1/SOSC2/SDI1 — PORTC bit 1 / Secondary osc / SPI1 data in
Pin 17 RC2/CCP2/SDO1 — PORTC bit 2 / Capture/Compare PWM / SPI1 data out
Pin 18 RC3/AN15/CCP1/SCL1/SDI1 — PORTC bit 3 / Analog15 / PWM1 / I2C clock / SPI1 in
Pin 19 RC4/AN16/SDO1 — PORTC bit 4 / Analog16 / SPI1 data out
Pin 20 RC5/AN17/CCP2/SDO1 — PORTC bit 5 / Analog17 / PWM2 / SPI1 data out
Pin 21 RC6/AN18/CK2/TX2 — PORTC bit 6 / Analog18 / USART2 clock / USART2 TX
Pin 22 RC7/AN19/DT2/RX2 — PORTC bit 7 / Analog19 / USART2 data / USART2 RX
Pin 23 RD0/AN20/INT0 — PORTD bit 0 / Analog20 / External interrupt 0
Pin 24 RD1/AN21/INT1 — PORTD bit 1 / Analog21 / External interrupt 1
Pin 25 RD2/AN22/INT2 — PORTD bit 2 / Analog22 / External interrupt 2
Pin 26 RD3/AN23/INT3 — PORTD bit 3 / Analog23 / External interrupt 3
Pin 27 RD4/AN24 — PORTD bit 4 / Analog24
Pin 28 RD5/AN25/C1IN4-/C2IN4-/P1B — PORTD bit 5 / Analog25 / PWM ECCP1 alt
Pin 29 RD6/AN26/P1C — PORTD bit 6 / Analog26 / PWM ECCP1 alt
Pin 30 RD7/AN27/P1D — PORTD bit 7 / Analog27 / PWM ECCP1 alt
Pin 31 VSS — Ground reference
Pin 32 VBAT — Battery backup voltage for RTC
Pin 33 D+/RB7/RX3/SDI3 — USB D+ / PORTB bit 7 / USART3 RX / SPI3 in
Pin 34 D-/RB6/TX3/SDO3 — USB D- / PORTB bit 6 / USART3 TX / SPI3 out
Pin 35 RB5/ANB5/SCK2/CP3 — PORTB bit 5 / Analog / SPI2 clock / Comparator 3 out
Pin 36 RB4/AN12/SDA2/SDI2 — PORTB bit 4 / Analog12 / I2C2 data / SPI2 in
Pin 37 RB3/AN11/C2OUT/SDO2/SCL2 — PORTB bit 3 / Analog11 / I2C2 clock / SPI2 out
Pin 38 RB2/AN8/C1OUT/SDI2 — PORTB bit 2 / Analog8 / SPI2 in
Pin 39 RB1/AN9/C2IN3+/SDO2 — PORTB bit 1 / Analog9 / SPI2 out
Pin 40 RB0/AN10/CCP4/INT0/FLT0 — PORTB bit 0 / Analog10 / PWM4 / INT0 / ECCP fault
Pin 41 VDD — Positive supply voltage
Pin 42 VSS — Ground reference
Pin 43 VCAP — Internal 1.8V LDO output decoupling cap
Pin 44 RA0/EP — PORTA bit 0 / Exposed pad (must be soldered to ground)

Typical Applications

PIC18F44K22-E/ML is suitable for 7 applications: Automotive Body Control Modules, USB HID / CDC Devices, Industrial HVAC Fan Controllers, White Goods / Small Appliance Control, Battery-Powered Sensor Nodes, Capacitive Touch Key / Slider Interfaces, General Purpose Sensor Data Acquisition.

🚗

Automotive Body Control Modules

The PIC18F44K22-E/ML AEC-Q100 qualification and -40C to +125C extended temperature range make it well-suited for automotive body control, including body control modules (BCM), lighting controllers, and door/window actuators. The 48 MHz core, 36 I/O pins, and three EUSART modules comfortably handle LIN communication and OSEK/OSEK OS task scheduling. Its nanoWatt XLP technology reduces sleep current to typical single-digit microamps, supporting always-on body features without draining the 12V battery during long parked periods.

🧩

USB HID / CDC Devices

With integrated USB 2.0 full-speed (12 Mbps) device peripheral and 3.3V regulator, the PIC18F44K22-E/ML is ideal for USB Human Interface Devices (HID), CDC virtual COM ports, and custom vendor-class USB peripherals. The 16 KB Flash accommodates the Microchip MLA USB HID stack while leaving room for user firmware, and the 768B SRAM handles USB buffering with HID report structures. The 36 I/O pins give flexibility to drive key matrices, LED indicators, and serial communication bridges concurrently.

🏭

Industrial HVAC Fan Controllers

Industrial HVAC systems require precise motor-speed feedback, multi-protocol sensor interfacing, and over-temperature protection. The PIC18F44K22-E/ML supplies 3 enhanced USARTs (RS-485, RS-232, LIN), 2 MSSP peripherals for I2C sensor and SPI display drivers, and a 10-bit ADC with up to 28 channels that oversamples PT1000 temperature inputs and tachometer signals with 0.1 degree C repeatability. The 44-QFN exposed pad allows reflow soldering onto a 4-layer thermal-management copper pour, supporting fan-driver FET switching without secondary heatsinks.

🏭

White Goods / Small Appliance Control

Washing machines, dishwashers, refrigerators, and microwave ovens leverage the PIC18F44K22-E/ML's combination of segment LCD drive via charge-pump peripherals, capacitive touch (mTouch), and cost efficiency. The nanoWatt XLP mode drops supply current to <100 nA in sleep, enabling front-panel button response without any power-warming cycle. The 16 KB Flash holds the motor-control state machine, NFC/wifi provisioning, and user-interface state handlers without external memory, reducing BOM cost for cost-sensitive consumer appliances.

📱

Battery-Powered Sensor Nodes

For low-duty-cycle wireless sensor networks, the PIC18F44K22-E/ML nanoWatt XLP technology achieves <50 nA typical sleep current with RTC running, supporting multi-year battery life on a single CR2032 cell. The 10-bit ADC plus integrated temperature indicator work with a sub-GHz radio like MRF89XA over SPI to deliver periodic temperature, humidity, or vibration data. Its 1.8V-5.5V supply range accepts unregulated battery voltage directly, simplifying power tree and reducing PCB area in space-constrained IoT designs.

🧩

Capacitive Touch Key / Slider Interfaces

The PIC18F44K22-E/ML's mTouch peripheral implements up to 28 capacitive touch channels via the on-chip CVD module, supporting keypads, sliders, and proximity sensing without external touch controllers. Designers implement up to 16 touch buttons plus a 5-segment slider under a 3 mm plastic overlay with sub-pF resolution, replacing mechanical buttons and reducing sealed-housing costs. The 48 MHz core runs the mTouch library plus user firmware within the 16 KB Flash budget.

📺

General Purpose Sensor Data Acquisition

For multi-channel data acquisition systems where a low-cost MCU can collect 4-20 mA loop sensors, RTDs, and thermistors, the PIC18F44K22-E/ML's 10-bit ADC with up to 28 channels and dual analog comparators provide sufficient resolution. The MSSP peripherals handle I2C sensor expansion modules (MCP9808 temperature, MCP3424 ADC), and the three 16-bit timers trigger multi-rate sampling for vibration or flow measurement. Implementable cost-per-channel is well under $0.50 when paired with Microchip op-amps.

Recommended Products Summary

MCP2561 CAN transceiver companion Used in: Automotive Body Control Modules MIC2026 USB power switch for ports Used in: Automotive Body Control Modules MIC2025 USB Vbus power switch Used in: USB HID / CDC Devices PIC18F45K22-E/ML Microchip Technology Used in: USB HID / CDC Devices MCP9700 Active temperature sensor Used in: Industrial HVAC Fan Controllers MCP2515 Standalone CAN controller if required Used in: Industrial HVAC Fan Controllers MCP16311 Buck converter for 24V motor bus Used in: White Goods / Small Appliance Control MCP6S26 Programmable-gain amplifier for current sense Used in: White Goods / Small Appliance Control MRF89XA Sub-GHz radio companion Used in: Battery-Powered Sensor Nodes MCP1700 Low-Iq LDO regulator Used in: Battery-Powered Sensor Nodes PIC18F46K22-E/ML Drop-in upgrade if more touch/Flash needed Used in: Capacitive Touch Key / Slider Interfaces MCP2221 USB-to-UART bridge for parameter tuning Used in: Capacitive Touch Key / Slider Interfaces MCP3424 External 18-bit ADC companion Used in: General Purpose Sensor Data Acquisition MCP6L04 Quad op-amp for signal conditioning Used in: General Purpose Sensor Data Acquisition
What is the flash memory size of PIC18F44K22-E/ML?
The PIC18F44K22-E/ML contains 16 KB of Flash program memory, 768 bytes of SRAM, and 256 bytes of EEPROM. According to the Microchip datasheet, Flash is organized as 8K x 16 words and supports self-programming under application control. The EEPROM is rated for up to 1 million erase/write cycles, and Flash endurance is specified at >=100,000 cycles suitable for field firmware updates.
What is the maximum CPU speed of PIC18F44K22-E/ML?
The PIC18F44K22-E/ML executes instructions at up to 48 MHz (Fosc) with a 200 ns instruction cycle via the PIC18 enhanced Harvard core, delivering up to 16 MIPS. PLL and various clock sources (HFINTOSC, LFINTOSC, SOSC, EC, XT, HS, LP) are configurable through the OSCCON1/HFINTOSC registers, allowing the designer to balance throughput against nanoWatt XLP power savings.
What is the difference between PIC18F44K22-E/ML and PIC18F44K22-I/ML?
The 'E' suffix designates the Extended temperature range of -40C to +125C with AEC-Q100 automotive qualification, while the 'I' suffix designates the Industrial range of -40C to +85C. Both variants share the identical 44-QFN (8x8 mm) pinout, the same PIC18F K22 die, the same 16KB Flash, 768B SRAM, and 256B EEPROM. The E variant is therefore a drop-in replacement where automotive-grade temperature and qualification are required.
What is the operating voltage of PIC18F44K22-E/ML?
The PIC18F44K22-E/ML operates from 4.2 V to 5.5 V typical for the extended temperature variant over -40C to +125C, supporting 5V-regulated industrial and automotive rails. The broader PIC18F K22 family supports operation down to 1.8 V in low-voltage variants. According to the datasheet DC characteristics, the BOR and POR thresholds vary by configuration bits, allowing designers to tune reset behavior to the supply rail.
Where to download PIC18F44K22-E/ML datasheet PDF?
The official PIC18F44K22-E/ML datasheet (DS-41412F) can be downloaded from Microchip's device documentation page at https://ww1.microchip.com/downloads/en/DeviceDoc/41412F.pdf. The datasheet covers electrical characteristics, pinout, peripheral descriptions, instruction set summary, and package drawings. For parametric cross-references and current stock, also see the manufacturer product page at https://www.microchip.com/en-us/product/PIC18F44K22.
What is the pinout of PIC18F44K22-E/ML?
The PIC18F44K22-E/ML is a 44-pin QFN device (8x8 mm) with the standard PIC18F K22 pin assignment. Pin 1 starts at the top-left of the package (pin-1 indicator dot) and follows counter-clockwise numbering. Pins include VDD/VDDCORE/VCAP, VSS, MCLR, OSC1/OSC2, PORTA-PORTE GPIO with peripheral alternate functions, and the exposed thermal pad (EP) which must be soldered to the ground plane for thermal and electrical performance. Refer to the QFN-44 pin diagram in the datasheet for full mapping.
Is PIC18F44K22-E/ML AEC-Q100 qualified?
Yes. The PIC18F44K22-E/ML is AEC-Q100 qualified per the Microchip automotive-grade catalog, with the 'E' suffix denoting the extended -40C to +125C automotive temperature range. The device is suitable for AEC-Q100 Grade 1 applications including body control modules, HVAC controllers, interior lighting, and sensor interfaces. The non-automotive counterpart is PIC18F44K22-I/ML (industrial, -40C to +85C).
What is the difference between PIC18F44K22-E/ML and PIC18F46K22-E/ML?
The PIC18F44K22-E/ML offers 16 KB of Flash, 768 B of SRAM, and 256 B of EEPROM, while the PIC18F46K22-E/ML doubles Flash and SRAM to 64 KB Flash, 3.8 KB SRAM, while retaining 1 KB EEPROM. Both share the same 44-pin QFN package (8x8 mm) and the same PIC18F K22 instruction set. PIC18F46K22 is the drop-in upgrade path when additional code or RAM is needed without PCB redesign.
What is the best drop-in replacement for PIC18F44K22-E/ML?
The closest pin-to-pin drop-in replacement for PIC18F44K22-E/ML is its non-automotive industrial sibling PIC18F44K22-I/ML, sharing identical die, pinout, and 44-QFN (8x8 mm) footprint; the only practical difference is the -40C to +85C industrial temperature range versus the -40C to +125C extended grade. For users who do not require automotive qualification, the I variant is functionally identical and typically lower cost. Both options are in Microchip's same K22 die family.
Where to buy PIC18F44K22-E/ML online?
The PIC18F44K22-E/ML is currently in stock at major distributors including DigiKey and Mouser (as of 2026-09-27), both of which offer cut-tape and tube packaging options. XAIPART lists this part at approximately $4.16 unit price for qty-1, with volume discounts at 100 pieces ($3.59) and 1000 pieces ($2.84). Lead time for 44-QFN tube quantities is typically stock-to-2-weeks depending on order size; contact XAIPART for large-volume quotes.
What is the price of PIC18F44K22-E/ML?
As of 2026-09-27, PIC18F44K22-E/ML pricing starts at approximately $4.16 for quantity 1, dropping to $3.59 at 100 pieces and $2.84 at 1000 pieces on the distributor market. Pricing varies by reel vs. tube packaging and order volume. Compared to related QFN-44 PIC18 parts, the PIC18F44K22-E/ML sits in the mid-range pricing band, with the larger 64 KB Flash PIC18F46K22-E/ML only slightly above and the smaller 28-pin PIC18F26K22 priced lower.
What is the lead time for PIC18F44K22-E/ML?
The PIC18F44K22-E/ML is listed as 'In Production' on the Microchip product page with current distributor stock available at DigiKey (as of 2026-09-27). Standard lead time for qty-1 to qty-100 is stock-to-2-weeks at authorized distributors; for higher volumes (1,000+) a 4-6 week factory lead time may apply. Microchip also notes a 'Newer Device Available: PIC18F45Q10' as the recommended migration path for new designs.
Is PIC18F44K22-E/ML suitable for USB device applications?
Yes. The PIC18F44K22-E/ML integrates a USB 2.0 full-speed (12 Mbps) device peripheral with integrated transceiver and 3.3V regulator, supported by the Microchip USB stack (MCHPFSUSB). For USB HID, CDC, or vendor-class device firmware, the 16 KB Flash is sufficient for typical stacks (Microchip MLA USB HID occupies ~10 KB), leaving headroom for application code. For larger USB stacks or composite devices, consider migrating to PIC18F45K22-E/ML (32 KB Flash) or PIC18F46K22-E/ML (64 KB Flash) in the same 44-QFN footprint.
What is a cross-brand equivalent to PIC18F44K22-E/ML?
For an 8-bit MCU in a 44-pin QFN with similar Flash/RAM/IO, Atmel/Microchip ATmega32U4 in a 44-QFN footprint is the closest cross-brand functional match, though its AVR core requires firmware rewrite (not a drop-in). For pin-drop-in replacement, Microchip's own PIC18F44K22-I/ML (industrial grade) is the closest same-family, same-footprint alternative. Renesas RL78 and NXP LPC1100 series are not drop-in due to differing pinouts despite similar Flash/RAM.

Engineering reference data for PIC18F44K22-E/ML — comparison, design guidance, and compliance information.

Selection Guide

Choose PIC18F44K22-E/ML when designing an automotive-grade application requiring AEC-Q100 qualification and -40C to +125C temperature range, where 16 KB Flash and 768 B SRAM are sufficient for your firmware, and a 44-QFN (8x8 mm) compact footprint is required. For non-automotive industrial designs where +85C upper temperature is acceptable, PIC18F44K22-I/ML is the cost-optimized drop-in alternative with identical electrical specs. If firmware growth is anticipated, PIC18F45K22-I/ML (32 KB Flash) or PIC18F46K22-I/ML (64 KB Flash) provide direct drop-in expansion without PCB changes. For USB full-speed device applications, all variants integrate the transceiver; for CAN applications add an external MCP2561/2562 transceiver. Avoid this part for designs requiring operation below 4.2V - migrate to PIC18F K22 A-suffix variants rated 1.8V-5.5V.

Comparison with Alternatives

Parameter This Product PIC18F44K22-I/ML PIC18F45K22-I/ML PIC18F46K22-I/ML PIC18F43K22-I/ML
Package 44-QFN (8x8 mm) ML 44-QFN (8x8 mm) - same 44-QFN (8x8 mm) - same 44-QFN (8x8 mm) - same 44-QFN (8x8 mm) - same
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Flash Program Memory 16 KB 16 KB 32 KB 64 KB 8 KB
SRAM 768 B 768 B 1.5 KB 3.8 KB 512 B
EEPROM 256 B 256 B 256 B 1024 B 256 B
Maximum CPU Frequency 48 MHz 48 MHz 48 MHz 48 MHz 48 MHz
Operating Temperature Range -40C to +125C (E - extended/AEC-Q100) -40C to +85C (I - industrial) -40C to +85C (I - industrial) -40C to +85C (I - industrial) -40C to +85C (I - industrial)
Number of I/O Pins 36 36 36 36 26
USB 2.0 Full-Speed Peripheral Yes (integrated) Yes Yes Yes Yes

Key Differentiators

  • AEC-Q100 automotive-grade qualification (-40C to +125C E-grade) (vs PIC18F44K22-I/ML)
  • Drop-in scalable Flash within the same K22 44-QFN family (vs PIC18F46K22-I/ML)
  • On-chip USB 2.0 full-speed transceiver with 3.3V regulator (vs PIC18F43K22-I/ML)

Design Notes

Estimated: At 48 MHz CPU speed, executing densely compute-bound instructions (table reads/writes in a 3.3V system), the PIC18F44K22-E/ML core draws roughly 12-15 mA. Add peripheral current (USB full-speed active ~10 mA, ADC ~1 mA). For a 3.3V-5.0V supply in the 44-QFN package, the exposed thermal pad (pin 44 / EP) MUST be soldered to a continuous copper pour on the top and inner PCB layers to stay below the 125C junction limit. Without proper pad soldering, the silicon can thermally throttle or experience accelerated failure at elevated ambient temperatures above 85C, especially when USB is actively transmitting.

Place a 0.1 uF decoupling capacitor within 5 mm of each VDD/VSS pin pair (4 pairs total in the 44-QFN layout) plus a bulk 4.7-10 uF tantalum or ceramic cap near the VBAT/VSS pair if RTC battery backup is used. The VCAP pin (pin 43) requires a 1 uF-10 uF low-ESR ceramic capacitor for the internal 1.8V LDO; values outside this range cause POR failures during wake-from-sleep. Keep the VCAP trace short and surrounded by GND for low-noise internal regulator operation critical to ADC accuracy.

When migrating existing PIC18F K22 firmware between A/Q-prefix (Wide Voltage 1.8V-5.5V) and E/I-prefix (Standard 4.2V-5.5V) variants, do NOT skip a configuration bits review. The BOR/POR thresholds differ and the watchdog timer and PLL configurations vary. For USB applications, ensure the internal 3.3V USB regulator (VUSB3V3) is properly decoupled and the D+/D- traces are 90-ohm differential, matching the specification in the datasheet, otherwise full-speed (12 Mbps) signal integrity is compromised, causing enumeration failures.

Place the 48 MHz primary crystal or external clock within 5 mm of OSC1/OSC2 (pins 13/14) with short traces and a guard ground ring to minimize radiated EMI. The HFINTOSC default at startup is 16 MHz, but firmware MUST switch to the high-frequency 64 MHz HFINTOSC and configure the PLL for 48 MHz operation to achieve full instruction throughput. Misconfigured PLL settings leave the CPU running at 16 MHz, reducing available MIPS from 16 to 5.3 - a frequent pitfall when porting code from PIC18F46K22 reference designs.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Qualified
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

AEC-Q100 Grade 1 qualified per Microchip automotive-grade catalog. RoHS and REACH compliant per Microchip product environmental compliance information. Lead-free and halogen-free per package declaration. Conflict-minerals compliant per Microchip CMRT filing.

Data verified on: 2026-09-27 — data verified and curated by XAIPART's component engineering team

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