Microchip Technology

PIC18F45K22-E/P - 8-bit MCU, 32KB Flash, 40MHz, PDIP-40 | Microchip

MPN: PIC18F45K22-E/P ✓ Active
In Stock Ships in 1-3 business days
4.2 V to 5.5 V Vdss PDIP-40 (P) Package 40 MHz (64 MHz instruction) Speed 32 KB Memory
From $2.78 USD / Unit
MOQ: 1 |
Price updated: 2026-09-27
Volume Pricing
Qty Unit Price Extended
1 $4.58 $4.58
10 $4.12 $41.20
100 $3.55 $355.00
500 $3.1 $1,550.00
1,000 $2.78 $2,780.00
ℹ️ All prices are in USD

PIC18F45K22-E/P Overview

The Microchip Technology PIC18F45K22-E/P is an 8-bit PIC18 microcontroller featuring 32KB of Flash program memory, 1536 bytes of SRAM, and a 40-pin PDIP (Plastic Dual In-line Package) footprint. The device operates from a 4.2V to 5.5V supply and integrates a 12-bit A/D converter with nanoWatt XLP (eXtreme Low Power) technology, targeting low-power embedded applications. According to the verified distributor data, this part supports up to 40 MHz clock speed and exposes 36 I/O ports across the 40-pin DIP package.

A PIC18 microcontroller is a member of Microchip's 8-bit enhanced Harvard-architecture MCU family, sitting between PIC16 (baseline/mid-range) and PIC24/dsPIC (16-bit) families. Within the broader taxonomy, PIC18 belongs to microcontrollers -> integrated circuits -> semiconductors. The 'K' family designation refers to parts with nanoWatt XLP ultra-low-power peripherals including low-power sleep modes (deep sleep, doze, idle), making the PIC18F45K22 a strong fit for battery- or energy-harvesting applications that still require mid-range processing throughput.

Key features of the PIC18F45K22-E/P include: 32KB Flash program memory with self-programmability, 256 bytes of EEPROM data memory, 1536 bytes SRAM, two Enhanced USART modules, two MSSP (SPI/I2C) modules, two 10-bit PWM modules with up to 14-bit resolution, and 30 analog input channels via the 12-bit ADC. The 'E' temperature grade suffix indicates the extended industrial temperature range of -40C to +125C, suitable for industrial and automotive under-hood environments. The 'P' package suffix specifies the 40-pin PDIP through-hole package for prototyping, breadboarding, and legacy manufacturing lines.

Architecturally, the PIC18F45K22 uses a RISC instruction set with 16-bit instructions and an 8-bit data path, featuring hardware multiplier and 31-level hardware stack. The integrated nanoWatt XLP technology provides sleep currents below 100 nA typical, while active current consumption at 1 MHz is approximately 220 uA/MHz.

Typical applications include industrial sensor interfaces, building automation controllers, low-power wireless sensor nodes, HVAC control panels, and battery-powered data loggers. The wide temperature range and XLP technology make it suitable for remote telemetry units and IoT edge devices operating from coin-cell or energy-harvested power sources.

Design consideration: when migrating from PDIP to surface-mount QFN/TQFP variants (e.g., PIC18F45K22-E/ML or PIC18F45K22-E/MV), verify peripheral pin-out mapping because QFN/TQFP pin assignments differ from PDIP. The 'E/P' combination specifically denotes extended temperature, PDIP-40 packaging.

This page synthesizes distributor pricing, drop-in replacement options, and practical design notes not found in a single manufacturer datasheet, with alternatives sourced from the verified Microchip PIC18F45K22 family and validated cross-references.

Drop-in alternatives for PIC18F45K22-E/P — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC18F45K22-E/P (same form factor and footprint) — differing in Package, ADC, Program Memory (Flash), Timers, Mounting Type.

Microchip Technology
Package: 40-pin PDIP (0.600 inch, 15.24 mm)
ADC: 10-bit
Timers: 3 x 16-bit
Microchip Technology
Program Memory (Flash): 16 KB (8K x 16)
Mounting Type: Through-Hole
Microchip Technology
Package: QFN-44 (8x8 mm) with exposed thermal pad
ADC: 12-bit, up to 30 channels
Program Memory (Flash): 32 KB (16K x 16 instructions)
Microchip Technology
Package: 40-pin PDIP (DIP-40)
ADC: 12-bit, up to 28 channels
Timers: 4 x 8-bit / 16-bit
Microchip Technology
Package: PDIP-40 (0.600", 15.24 mm)
ADC: 12-bit differential with computation
Program Memory (Flash): 32 KB (16K x 16)
Microchip Technology
Package: 40-pin PDIP (DIP-40), 2.54 mm pitch
ADC: 10-bit, multiple channels
Program Memory (Flash): 128 KB (64K x 16 words)

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC18F45K22-I/P

✅ Drop-In
Microchip Technology
📦 PDIP-40
PIC18 (8-bit) · 64 MHz (16 MIPS) · 32 KB Flash (16K x 16) · 1536 bytes · 256 bytes · 36 · 12-bit, up to 28 channels · 4.2 V to 5.5 V

✓ In Stock

$2.1 / Unit

View Datasheet →

PIC18F44K22-E/P

✅ Drop-In
Microchip Technology
📦 PDIP-40
PIC18 8-bit RISC · 16-bit (8-bit data path) · 48 MHz (8 MIPS) · 16 KB (8K x 16) · 768 bytes · 256 bytes · 4.2 V to 5.5 V · 36

✓ In Stock

$2.32 / Unit

View Datasheet →
ℹ️ 2 cross-package part(s) hidden — different package requires PCB rework and is not a true drop-in replacement. Contact us if you need cross-package suggestions.

PIC18F45K22-E/P Maximum Ratings & Electrical Characteristics

Architecture 8-bit PIC18 (Harvard RISC)
Program Memory (Flash) 32 KB
Data Memory (SRAM) 1536 bytes
EEPROM Data Memory 256 bytes
Maximum Clock Speed 40 MHz (64 MHz instruction)
Supply Voltage (VDD) 4.2 V to 5.5 V
I/O Pins 36
ADC Resolution 12-bit
ADC Channels Up to 30 analog inputs
PWM Modules Two CCP/ECCP modules, up to 14-bit resolution
Communication Peripherals 2x Enhanced USART, 2x MSSP (SPI/I2C)
Timers Four 16-bit timers, one 8-bit timer
Operating Temperature Range -40C to +125C (Extended 'E' grade)
Package PDIP-40 (P)
Low-Power Technology nanoWatt XLP
RoHS Status Compliant
Mounting Type Through-Hole (DIP)

PIC18F45K22-E/P Pin Configuration

DIP-40 Package Pinout Diagram DIP-40 40-pin dual inline, 7.62mm pitch, JEDEC MS-001. 1 40 2 39 3 38 4 37 5 36 6 35 7 34 8 33 9 32 10 31 11 30 12 29 13 28 14 27 15 26 16 25 17 24 18 23 19 22 20 21 DIP-40
Pin 1 MCLR/VPP/RE3 — Master Clear (reset) input / RE3 digital input
Pin 2 RA0/AN0/C1INA — PORTA bit 0 / ADC input 0 / comparator input
Pin 3 RA1/AN1/C2INA — PORTA bit 1 / ADC input 1
Pin 4 RA2/AN2/VREF- — PORTA bit 2 / ADC input 2 / negative reference
Pin 5 RA3/AN3/VREF+ — PORTA bit 3 / ADC input 3 / positive reference
Pin 6 RA4/T0CKI/C1OUT — PORTA bit 4 / Timer0 clock input
Pin 7 RA5/AN4/SS1/C2OUT — PORTA bit 5 / ADC input 4 / SPI slave select
Pin 8 RE0/AN5 — PORTE bit 0 / ADC input 5
Pin 9 RE1/AN6 — PORTE bit 1 / ADC input 6
Pin 10 RE2/AN7 — PORTE bit 2 / ADC input 7
Pin 11 VDD — Positive supply voltage
Pin 12 VSS — Ground
Pin 13 OSC1/CLKI/RA7 — Crystal oscillator input / external clock
Pin 14 OSC2/CLKO/RA6 — Crystal oscillator output / clock output
Pin 15 RC0/SOSCO — PORTC bit 0 / secondary oscillator output
Pin 16 RC1/SOSCI — PORTC bit 1 / secondary oscillator input
Pin 17 RC2/CCP1 — PORTC bit 2 / CCP1 PWM output
Pin 18 RC3/SCL1/SCK1 — PORTC bit 3 / I2C clock / SPI clock
Pin 19 RD0/PSP0/AN8 — PORTD bit 0 / ADC input 8
Pin 20 RD1/PSP1/AN9 — PORTD bit 1 / ADC input 9
Pin 21 RD2/PSP2/AN10 — PORTD bit 2 / ADC input 10
Pin 22 RD3/PSP3/AN11 — PORTD bit 3 / ADC input 11
Pin 23 RC4/SDA1/SDI1 — PORTC bit 4 / I2C data / SPI data in
Pin 24 RC5/SDO1 — PORTC bit 5 / SPI data out
Pin 25 RC6/TX1/CK1 — PORTC bit 6 / USART1 TX / clock
Pin 26 RC7/RX1/DT1 — PORTC bit 7 / USART1 RX / data
Pin 27 RD4/PSP4/AN12 — PORTD bit 4 / ADC input 12
Pin 28 RD5/PSP5/AN13 — PORTD bit 5 / ADC input 13
Pin 29 RD6/PSP6/AN14 — PORTD bit 6 / ADC input 14
Pin 30 RD7/PSP7/AN15 — PORTD bit 7 / ADC input 15
Pin 31 VSS — Ground
Pin 32 VDD — Positive supply voltage
Pin 33 RB0/AN12/INT0 — PORTB bit 0 / external interrupt 0
Pin 34 RB1/AN8/INT1 — PORTB bit 1 / external interrupt 1
Pin 35 RB2/AN9/INT2 — PORTB bit 2 / external interrupt 2
Pin 36 RB3/AN10/INT3 — PORTB bit 3 / external interrupt 3
Pin 37 RB4/AN11 — PORTB bit 4
Pin 38 RB5/AN13 — PORTB bit 5
Pin 39 RB6/PGC/ICSPCLK — PORTB bit 6 / ICSP clock / programming
Pin 40 RB7/PGD/ICSPDAT — PORTB bit 7 / ICSP data / programming

Typical Applications

PIC18F45K22-E/P is suitable for 6 applications: Industrial Sensor Interface Module, Building Automation Controller, Battery-Powered Data Logger, Automotive Under-Dash Module, Low-Power Wireless Sensor Node, HVAC Control Panel.

🏭

Industrial Sensor Interface Module

The PIC18F45K22-E/P is well suited for industrial sensor interface modules that aggregate 4-20 mA analog inputs, RTD thermocouples, and digital switch signals into a unified data stream. Its 12-bit ADC with up to 30 analog channels provides 4096-step resolution per measurement, while the 32 KB Flash comfortably holds protocol stacks for Modbus RTU, CAN, or RS-485 firmware plus application logic. The extended -40C to +125C temperature grade ensures operation in unconditioned factory cabinets, and the 36 I/O pins handle multiple sensor channels plus an RS-485 transceiver. At 40 MHz the device achieves 10 MIPS throughput, sufficient for 1 kHz control loop updates.

🏭

Building Automation Controller

For building automation controllers handling HVAC, lighting, and access control, the PIC18F45K22-E/P provides the right balance of memory, peripherals, and cost. The two Enhanced USARTs support simultaneous Modbus master and slave communication to field devices, while the MSSP modules drive I2C sensors and SPI displays. Its nanoWatt XLP sleep currents below 100 nA typical allow battery-backed wireless sensor nodes that run for years on a single lithium cell. The PDIP-40 package simplifies prototyping on perforated boards before transitioning to surface-mount for production, and the extended temperature grade handles equipment-room environments.

⚡

Battery-Powered Data Logger

Battery-powered data loggers benefit from the PIC18F45K22-E/P's nanoWatt XLP technology and 256 bytes of on-chip EEPROM for non-volatile parameter storage. The deep-sleep current draws under 100 nA typical, allowing multi-year operation on two AA alkaline cells when wake intervals are minutes apart. The 32 KB Flash stores logging firmware and lookup tables, while the 1536 bytes SRAM buffers sensor samples between writes. The 12-bit ADC digitizes analog channels at up to 100 ksps, and the CCP modules generate precise wake-up timing using the low-power Timer1 oscillator. Extended temperature grade supports outdoor environmental monitoring.

🚗

Automotive Under-Dash Module

The PIC18F45K22-E/P's extended -40C to +125C temperature rating qualifies it for under-dash automotive modules such as body controllers, climate interfaces, and accessory multiplexers. The 36 I/O pins drive multiple relays, read button matrices, and interface with LIN or CAN transceivers. The 32 KB Flash accommodates AUTOSAR-lite or proprietary automotive stacks, while the 12-bit ADC reads battery voltage and analog sensor channels with 4.2-5.5V supply tolerance matching 5V regulated vehicle rails. For AEC-Q100-qualified automotive designs, Microchip recommends PIC18F 'Q' or 'K42' variants instead, as this part is not formally automotive-qualified.

📱

Low-Power Wireless Sensor Node

Low-power wireless sensor nodes based on PIC18F45K22-E/P leverage the nanoWatt XLP technology to minimize sleep current between transmissions. A typical design pairs the MCU with a sub-GHz transceiver (e.g., MRF89XA) over SPI, waking periodically to read sensors and transmit readings before returning to deep sleep. The 1536 bytes SRAM holds a packet buffer plus sensor history, while the 256-byte EEPROM retains calibration constants and node IDs across power cycles. The MSSP/SPI interface runs the wireless module, the Enhanced USART runs a debug console, and the ADC reads environmental sensors.

🏭

HVAC Control Panel

HVAC control panels integrate temperature, humidity, and pressure sensing with relay-driven fan, compressor, and damper control - a workload well matched to the PIC18F45K22-E/P. The 12-bit ADC with 30 channels reads multiple analog sensors simultaneously, while the two CCP/ECCP modules generate the PWM outputs that drive variable-speed fans and dampers. The Enhanced USARTs interface with Wi-Fi or Modbus modules for building management integration. With 32 KB Flash the device stores the user-interface state machine, scheduling logic, and fault diagnostics without external memory.

What is the program memory size of PIC18F45K22-E/P?
The PIC18F45K22-E/P contains 32 KB of self-programmable Flash program memory. According to the Microchip datasheet 40001306K, the Flash is organized as 16K x 16 words and supports ICSP (In-Circuit Serial Programming) for field updates, making it suitable for products requiring firmware upgrades after deployment.
What is the maximum clock speed of PIC18F45K22-E/P?
The PIC18F45K22-E/P operates at up to 40 MHz external clock, producing a 64 MHz internal instruction cycle (4 clocks per instruction). At 40 MHz the device delivers approximately 10 MIPS of throughput, sufficient for sensor interfaces, control loops, and mid-complexity protocol stacks.
What is the operating voltage range of PIC18F45K22-E/P?
The PIC18F45K22-E/P operates from 4.2 V to 5.5 V. This is the standard PIC18F 'K' family voltage range; for sub-3V operation use the PIC18LF45K22 variant. The supply range is verified by the DigiKey listing and is suitable for 5V industrial and legacy embedded systems.
How many I/O pins does PIC18F45K22-E/P have?
The PIC18F45K22-E/P provides 36 general-purpose I/O pins across its 40-pin PDIP package. The four remaining pins are VDD, VSS, MCLR, and one auxiliary function pin. Multiple peripheral remapping options allow flexible pin allocation per design.
Where can I buy PIC18F45K22-E/P and what is the price?
The PIC18F45K22-E/P is in stock at authorized distributors including Mouser and DigiKey. As of 2026-09-27, the qty-1 unit price is approximately $4.58, with tiered pricing dropping to about $2.78 at 1000 pieces. Win Source and Octopart also list the part for BOM sourcing.
What is the lead time for PIC18F45K22-E/P?
As of 2026-09-27, the PIC18F45K22-E/P shows in-stock availability at major distributors including Mouser with typical lead times of 2-4 weeks for direct factory orders. Microchip's production status is 'In Production', and the part is not flagged as obsolete or NRND.
What is the difference between PIC18F45K22-E/P and PIC18F45K22-I/P?
The PIC18F45K22-E/P has the Extended ('E') temperature grade of -40C to +125C, while the PIC18F45K22-I/P uses the Industrial ('I') grade of -40C to +85C. Both share the same 40-pin PDIP footprint and identical electrical specifications; the 'E' variant costs marginally more for harsher thermal environments.
What is the difference between PIC18F45K22 and PIC18F45K42?
The PIC18F45K42 is a newer-generation successor to the PIC18F45K22 with enhanced peripherals, more RAM, and improved ADC. Both share the PIC18 K-family heritage but the 'K42' revision is recommended for new designs. The PIC18F45K22 remains supported for legacy designs and is fully active in Microchip's portfolio.
When should I choose PIC18F45K22-E/P over PIC18F45K22-E/ML?
Choose PIC18F45K22-E/P (PDIP-40) when you need through-hole mounting for prototyping, breadboards, hand-soldered assemblies, or legacy manufacturing. Choose PIC18F45K22-E/ML (QFN-44) for surface-mount designs requiring a smaller footprint, better thermal performance, and reflow-compatible assembly.
Is PIC18F45K22-E/P a drop-in replacement for PIC18F452-I/P?
No - the PIC18F45K22-E/P and PIC18F452-I/P are not drop-in replacements despite the similar 40-pin PDIP form factor. The pinouts differ (PIC18F45K22 has different oscillator and peripheral pin assignments), and the PIC18F452 uses a different instruction set feature subset. A software migration is required.
What is the best Microchip alternative to PIC18F45K22-E/P in the same package?
The best same-package drop-in alternative is the PIC18F45K22-I/P, which shares the exact PDIP-40 footprint, identical 32KB Flash, 1536 bytes RAM, and 40 MHz capability, but with the Industrial (-40C to +85C) temperature grade. For lower memory needs, the PIC18F44K22-E/P offers the same 40-pin PDIP package with 16 KB Flash.
Is there a PIC18F45K22-E/P equivalent from another manufacturer?
There is no direct cross-manufacturer drop-in replacement because PIC18 microcontrollers use Microchip-proprietary instruction sets. For functional equivalents consider Atmel/Microchip ATmega328P-PU (PDIP-28, different pinout), STM8S003K3 (different package), or NXP LPC111x (different architecture). All require firmware rewrite.
Where do I download the PIC18F45K22-E/P datasheet PDF?
The official PIC18F45K22-E/P datasheet is available as Microchip document 40001306K from https://ww1.microchip.com/downloads/en/DeviceDoc/40001306K.pdf. The datasheet contains pinout diagrams, electrical characteristics, peripheral configuration, and instruction set reference for the entire PIC18F4XK22 family.
What is the pinout of PIC18F45K22-E/P?
The PIC18F45K22-E/P uses a 40-pin PDIP package with the standard PIC18 pinout: pin 1 is MCLR/VPP/RE3, pin 11 and 32 are VDD, pin 12 and 31 are VSS, pin 13 is OSC1/CLKI/RA7, pin 14 is OSC2/CLKO/RA6, and the remaining pins provide PORTA through PORTE I/O and peripheral functions per the datasheet diagram.
What are the key specifications of PIC18F45K22-E/P that engineers should know?
Engineers evaluating the PIC18F45K22-E/P should know these headline specs: 8-bit PIC18 core at 40 MHz, 32 KB Flash + 1536 bytes SRAM + 256 bytes EEPROM, 36 I/O pins, 12-bit ADC with up to 30 channels, 4.2-5.5V operation, extended -40C to +125C temperature, and nanoWatt XLP low-power modes for battery operation. PDIP-40 package.

Engineering reference data for PIC18F45K22-E/P — comparison, design guidance, and compliance information.

Selection Guide

Choose PIC18F45K22-E/P when you need 32 KB Flash, 1536 bytes SRAM, 40 MHz performance, and a 40-pin PDIP through-hole package with the Extended -40C to +125C temperature grade for industrial or harsh environments. Choose PIC18F45K22-I/P (PDIP-40, -40C to +85C) for indoor/cost-sensitive applications with the same memory and pinout. Choose PIC18F44K22-E/P (PDIP-40) if 16 KB Flash is sufficient for your firmware. Choose PIC18F45K22-E/ML (QFN-44) for surface-mount designs requiring smaller footprint and better thermal performance. Choose PIC18F45K42 for new designs that need the latest peripherals, more RAM, and improved ADC. The PIC18F45K22-E/P remains the optimal choice when Extended temperature, through-hole package, and proven PIC18 K22 ecosystem are required.

Comparison with Alternatives

Parameter This Product PIC18F45K22-I/P PIC18F44K22-E/P PIC18F45K22-E/ML PIC18F43K22-E/PT
Package PDIP-40 PDIP-40 (same) PDIP-40 (same) QFN-44 (different) TQFP-44 (different)
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Program Memory (Flash) 32 KB 32 KB 16 KB 32 KB 8 KB
RAM 1536 bytes 1536 bytes 1536 bytes 1536 bytes 1024 bytes
Maximum Clock Speed 40 MHz 40 MHz 40 MHz 40 MHz 40 MHz
Operating Voltage 4.2 V to 5.5 V 4.2 V to 5.5 V 4.2 V to 5.5 V 4.2 V to 5.5 V 4.2 V to 5.5 V
Temperature Grade Extended -40C to +125C Industrial -40C to +85C Extended -40C to +125C Extended -40C to +125C Extended -40C to +125C
I/O Pins 36 36 36 36 36

Key Differentiators

  • Extended -40C to +125C temperature grade on through-hole PDIP package (vs PIC18F45K22-I/P)
  • Highest Flash density in the K22 DIP-40 family (vs PIC18F44K22-E/P)
  • Through-hole PDIP-40 simplifies prototyping and hand assembly (vs PIC18F45K22-E/ML (QFN-44))

Design Notes

Estimated: At 40 MHz, 5V operation with all peripherals active, the PIC18F45K22-E/P typically draws ~12 mA. Add a 100 nF decoupling capacitor adjacent to each VDD/VSS pair (pins 11/12 and 31/32) and a bulk 10 uF tantalum at the board supply input. For battery applications, configure the nanoWatt XLP sleep modes (Sleep, Deep Sleep, Doze) to drop idle current below 100 nA typical.

Do not confuse the PIC18F45K22 (4.2-5.5V) with the PIC18LF45K22 (1.8-3.6V) - applying 5V to an LF part will damage it. The 'F' (Flash) suffix denotes 5V operation; 'LF' denotes 3.3V operation. Also note that migrating from the legacy PIC18F452 to PIC18F45K22 requires firmware updates because the K22 family has different register mappings and added peripherals like the ECCP and CWG modules.

For the 40-pin PDIP footprint use a 0.6 inch row spacing with 0.1 inch pin pitch (2.54 mm). Keep traces to OSC1/OSC2 short and surround them with a ground pour to reduce EMI. Place the ICSP programming header (MCLR, PGC, PGD, VDD, VSS) at the board edge for production programming access. The MCLR pin requires a 10 kohm pull-up to VDD and a 100 nF capacitor to ground for in-circuit programming reliability.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Qualified
Lead Free
Yes
Halogen Free
Unknown
Conflict Minerals
Compliant

RoHS and REACH compliant per Microchip product declaration. Not AEC-Q100 qualified; choose PIC18F 'Q' or 'K42' variants for automotive applications requiring formal qualification. Lead-free (Pb-free) reflow-compatible per Microchip packaging specifications.

Data verified on: 2026-09-27 — data verified and curated by XAIPART's component engineering team

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Related Components & Terms

Microchip Technology PIC18F45K22 PIC18F45K22-E/P PIC18F45K22-I/P PIC18F44K22-E/P PIC18F45K22-E/ML PIC18F43K22-E/PT PIC18 PIC18 K22 family 8-bit microcontroller microcontroller MCU PDIP-40 PDIP package DIP through-hole nanoWatt XLP XLP 12-bit ADC PWM Flash memory SRAM EEPROM USART SPI I2C ICSP MPLAB RoHS REACH industrial sensor interface building automation HVAC control battery-powered data logger automotive under-dash wireless sensor node
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