Microchip Technology

PIC18LF4553-I/ML - 8-bit 48MHz USB MCU 32KB Flash | Microchip

MPN: PIC18LF4553-I/ML ✓ Active
In Stock Ships in 1-3 business days
2.0 V to 5.5 V Vdss 44-VQFN Exposed Pad (ML) Package 48 MHz Speed 32 KB Flash Memory
From $5.1 USD / Unit
MOQ: 1 |
Price updated: 2026-09-28
Volume Pricing
Qty Unit Price Extended
1 $7.95 $7.95
10 $7.15 $71.50
100 $6.4 $640.00
500 $5.75 $2,875.00
1,000 $5.1 $5,100.00
ℹ️ All prices are in USD

PIC18LF4553-I/ML Overview

The Microchip Technology PIC18LF4553-I/ML is a low-voltage 8-bit PIC18 family microcontroller with integrated Full-Speed USB 2.0, packaged in a 44-pin VQFN (ML) with exposed thermal pad. It combines 32 KB of Enhanced Flash program memory, 2048 bytes of SRAM, and a 12-bit ADC with up to 13 channels, while running at up to 48 MHz (12 MIPS) from a 2.0-5.5 V supply. The 'LF' prefix indicates the wide VDD range and nanoWatt power-management features, making it suitable for both battery-powered and bus-powered designs.

An 8-bit microcontroller (MCU) is a single-chip computer that integrates a CPU, program memory, RAM, and peripherals. PIC18 microcontrollers use Microchip's enhanced Harvard RISC architecture, achieving 200 ns instruction execution and up to 12 MIPS throughput. Within the broader semiconductor taxonomy, MCUs sit under microcontrollers -> processors -> semiconductors, and they form the lowest tier of computing devices for embedded systems where cost, deterministic timing, and peripheral integration matter more than raw compute throughput.

Key features include Full-Speed USB 2.0 device/host/OTG support with an internal 3.3V regulator, a 10-bit ADC pre-scaler, two CCP/ECCP modules for PWM and capture/compare, I2C, SPI, and an enhanced USART for serial communication. The device also provides nanoWatt Technology with multiple idle/sleep modes, a programmable brown-out reset (BOR), a hardware watchdog timer (WDT), and high/low-voltage detect (HLVD) for robust operation in industrial environments. The on-chip 32 KB self-programmable flash supports boot-loader and in-application programming via USB, simplifying field firmware updates.

Architecturally, the PIC18LF4553 uses an enhanced 16-bit instruction word with 8-bit data paths and a 31-level hardware stack, providing deterministic interrupt response essential for real-time USB stacks. The internal 3.3V regulator can supply the USB transceiver while the core runs from 5V, eliminating the need for external LDO when designing USB peripherals on 5V rails.

Typical applications include USB HID peripherals such as custom keyboards and mice, USB-to-UART bridges, industrial data loggers with USB connectivity, and low-power sensor nodes that occasionally wake up to enumerate as USB devices. Designers should add a 1uF bypass capacitor near the VUSB3V3 pin and follow Microchip's USB hardware checklist for EMI/ESD compliance when targeting industrial temperature grades.

Drop-in alternatives for PIC18LF4553-I/ML — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC18F4553-I/ML

✅ Drop-In
📦 44-VQFN Exposed Pad (ML)
VDD 4.2-5.5 V (vs 2.0-5.5 V on LF), no nanoWatt low-power modes; identical flash/RAM/USB/peripherals

📋 Reference alternative (not in catalog)

PIC18LF4550-I/ML

✅ Drop-In
📦 44-VQFN Exposed Pad (ML)
32 KB Flash vs 32 KB Flash (same), 13 ADC channels vs 13 ADC channels, differs in peripheral subset (no ECCP2 on 4550)

📋 Reference alternative (not in catalog)

PIC18F4550-I/ML

✅ Drop-In
📦 44-VQFN Exposed Pad (ML)
5V-only variant of 4550 family, same 44-VQFN pinout, 32 KB flash, Full-Speed USB

📋 Reference alternative (not in catalog)

PIC18LF4455-I/ML

✅ Drop-In
📦 44-VQFN Exposed Pad (ML)
24 KB Flash (-25% vs 32 KB), 2048 B RAM, same 44-VQFN pinout and USB peripheral

📋 Reference alternative (not in catalog)

PIC18LF4458-I/ML

✅ Drop-In
📦 44-VQFN Exposed Pad (ML)
32 KB Flash (same), 2048 B RAM (same), no Full-Speed USB OTG controller

📋 Reference alternative (not in catalog)

PIC18LF4553-I/PT

✅ Drop-In
📦 44-TQFP (PT)
44-TQFP through-hole-friendly package (vs 44-VQFN ML); same silicon, same USB/ADC, pin-compatible at firmware level

📋 Reference alternative (not in catalog)

PIC18LF4553-I/ML Maximum Ratings & Electrical Characteristics

Core Processor PIC
Core Size 8-Bit
Series PIC 18F
Program Memory Size 32 KB Flash
RAM Size 2048 B
EEPROM Size 256 B
Maximum Clock Speed 48 MHz
Instruction Throughput 12 MIPS
Supply Voltage (VDD) 2.0 V to 5.5 V
Operating Temperature -40 C to +85 C (Industrial)
Package 44-VQFN Exposed Pad (ML)
Mounting Type Surface Mount
Connectivity I2C, SPI, UART/USART, USB
Peripherals Brown-out Detect/Reset, HLVD, POR, PWM, WDT
ADC Resolution 12-bit, up to 13 channels
USB USB 2.0 Full-Speed Device/Host/OTG with internal 3.3V regulator
RoHS Status Compliant
Lead-Free Yes

PIC18LF4553-I/ML Pin Configuration

Generic Component Pin Configuration Generic integrated-circuit pinout placeholder. Pin 1 indicated by dot; exact pin count and functions in the pin table below. 1 N 2 N-1 3 N-2 4 N-3 Pin Configuration See pin table below for pin functions Package-specific diagram not available
Pin 1 RA2 — Port A bit 2 / analog channel AN2
Pin 2 RA3 — Port A bit 3 / analog channel AN3 / VREF+
Pin 3 RA4 — Port A bit 4 / analog channel AN4
Pin 4 RA5 — Port A bit 5 / analog channel AN5 / HLVDIN
Pin 5 VSS — Ground reference
Pin 6 RA6 — Port A bit 6 / oscillator output
Pin 7 RA7 — Port A bit 7 / oscillator input
Pin 8 VDD — Positive supply voltage (2.0-5.5 V)
Pin 9 RE3 — Port E bit 3 / MCLR (programming/reset)
Pin 10 VUSB — USB power monitor / internal 3.3V regulator output
Pin 11 RB0 — Port B bit 0 / analog channel AN12
Pin 12 RB1 — Port B bit 1 / analog channel AN10
Pin 13 RB2 — Port B bit 2 / analog channel AN8
Pin 14 RB3 — Port B bit 3 / analog channel AN9 / CCP2
Pin 15 RB4 — Port B bit 4 / analog channel AN11
Pin 16 RB5 — Port B bit 5 / analog channel AN13
Pin 17 RB6 — Port B bit 6 / PGC (ICSP clock)
Pin 18 RB7 — Port B bit 7 / PGD (ICSP data)
Pin 19 VSS — Ground reference
Pin 20 VDD — Positive supply voltage (2.0-5.5 V)
Pin 21 RC0 — Port C bit 0 / analog channel AN4
Pin 22 RC1 — Port C bit 1 / analog channel AN5
Pin 23 RC2 — Port C bit 2 / analog channel AN6 / CCP1
Pin 24 VDD — Positive supply voltage (USB transceiver internal)
Pin 25 VSS — Ground reference (USB transceiver)
Pin 26 RC4 — Port C bit 4 / D- (USB data minus)
Pin 27 RC5 — Port C bit 5 / D+ (USB data plus)
Pin 28 RC6 — Port C bit 6 / TX (USART async transmit)
Pin 29 RC7 — Port C bit 7 / RX (USART async receive)
Pin 30 RD0 — Port D bit 0 / PSP data
Pin 31 RD1 — Port D bit 1 / PSP data
Pin 32 RD2 — Port D bit 2 / PSP data
Pin 33 RD3 — Port D bit 3 / PSP data
Pin 34 RD4 — Port D bit 4 / PSP data
Pin 35 RD5 — Port D bit 5 / PSP data
Pin 36 RD6 — Port D bit 6 / PSP data
Pin 37 RD7 — Port D bit 7 / PSP data
Pin 38 VSS — Ground reference
Pin 39 VDD — Positive supply voltage (2.0-5.5 V)
Pin 40 RE0 — Port E bit 0 / analog channel AN5
Pin 41 RE1 — Port E bit 1 / analog channel AN6
Pin 42 RE2 — Port E bit 2 / analog channel AN7
Pin 43 OSC1 — Oscillator input / external clock input
Pin 44 OSC2 — Oscillator output

Typical Applications

PIC18LF4553-I/ML is suitable for 6 applications: USB HID Peripherals (Keyboard / Mouse / Gamepad), USB-to-UART Bridge / Virtual COM Port, Industrial USB Data Logger, Battery-Powered USB Sensor Node, USB Host / OTG Embedded Controller, Educational USB Development Platform.

🎧

USB HID Peripherals (Keyboard / Mouse / Gamepad)

The PIC18LF4553-I/ML is purpose-designed for USB Human Interface Devices. Its Full-Speed USB 2.0 SIE plus internal 3.3V regulator eliminates the external LDO needed by most 5V MCUs, shrinking PCB area. With 32 KB flash and 12 MIPS, it runs Microchip's USB Framework HID class driver comfortably, including boot-loader-based field firmware updates. The 12-bit ADC and PWM peripherals support multi-channel analog inputs and RGB LED drive typical of premium gaming peripherals, while nanoWatt idle modes extend battery life in wireless HID dongles.

🌐

USB-to-UART Bridge / Virtual COM Port

The PIC18LF4553-I/ML's integrated USB SIE and enhanced USART allow it to implement CDC-class virtual COM port bridges without an external converter IC. With 48 MHz CPU and 2048 B RAM, throughput easily exceeds the 12 Mbps USB Full-Speed envelope for typical serial rates up to 921600 bps. The wide 2.0-5.5 V supply lets the same firmware serve both 3.3V MCUs and legacy 5V RS-232 gear via level shifters. Industrial-grade -40C to +85C operation makes it suitable for factory-floor serial bridges.

🏭

Industrial USB Data Logger

The 32 KB flash and 256 B EEPROM are sufficient for storing configuration and calibration tables in a USB-tethered industrial data logger. The 12-bit ADC with up to 13 channels digitizes multiple sensor inputs (temperature, pressure, 4-20 mA loops via shunt), while the 44-VQFN exposed pad dissipates heat during continuous USB-powered acquisition. Brown-out reset and HLVD guard against industrial supply glitches, and the -40C to +85C industrial temperature range supports factory environments. USB plug-and-play eliminates custom driver installation.

🔋

Battery-Powered USB Sensor Node

The 'LF' prefix denotes the 2.0-5.5 V wide-voltage nanoWatt variant, allowing the PIC18LF4553-I/ML to run from a single Li-ion cell (3.0-4.2 V) while charging and still maintaining USB enumeration. nanoWatt idle modes drop quiescent current below 100 nA in sleep, and the internal 3.3V regulator powers the USB pull-up only when connected. The 48 MHz core wakes from sleep, runs sensor acquisition, and pushes data over USB CDC or HID within milliseconds, preserving battery life between measurement intervals.

🖥️

USB Host / OTG Embedded Controller

In USB host mode the PIC18LF4553-I/ML can interface to USB mass storage, HID, or CDC devices, enabling embedded products that read USB flash drives or interface to USB printers without a PC. The 32 KB flash holds a simplified USB host stack plus FAT file-system library from Microchip. With 2048 B RAM, small file-buffer operations are feasible; for full mass-storage support, designers typically use the 4553 as co-processor alongside a higher-RAM MCU. The wide VDD range supports bus-powered host hubs from 5V supply.

🔧

Educational USB Development Platform

The PIC18LF4553-I/ML is a staple in university and hobbyist USB projects because Microchip's MPLAB X IDE, XC8 compiler, and USB Framework are free and well documented. With 32 KB flash it runs full HID, CDC, and bootloader examples, while the 44-VQFN breakout boards expose USB, ADC, PWM, and I/O pins for lab work. The 48 MHz core plus 12-bit ADC allows timing experiments and instrumentation projects at undergraduate level. The exposed thermal pad simplifies hand-soldering prototypes on standard breakout PCBs.

Recommended Products Summary

What is the program memory size of PIC18LF4553-I/ML?
The PIC18LF4553-I/ML has 32 KB of Enhanced Flash program memory. According to the Microchip datasheet, this flash is self-programmable under software control, supporting in-application and boot-loader programming via USB, which simplifies field firmware updates for USB peripherals and industrial data loggers.
Does PIC18LF4553-I/ML support USB 2.0?
Yes, the PIC18LF4553-I/ML integrates a Full-Speed USB 2.0 controller supporting device, host, and OTG operation. The on-chip 3.3V regulator powers the USB transceiver from a 5V VDD, eliminating the external LDO typically required for USB peripherals, and the SIE handles packet framing automatically to free the CPU.
What is the operating voltage range of PIC18LF4553-I/ML?
The PIC18LF4553-I/ML operates from 2.0 V to 5.5 V VDD, suitable for both 3.3V and 5V systems as well as battery-powered designs. The 'LF' prefix denotes the wide-voltage, nanoWatt variant; combined with its 12 MIPS throughput, it offers a strong performance-per-watt ratio for USB-enabled embedded nodes.
Where to buy PIC18LF4553-I/ML online?
The PIC18LF4553-I/ML is available through authorized Microchip distributors such as Mouser, DigiKey, and Microchip Direct, with stock in 44-VQFN tape-and-reel packaging as of 2026-09-28. For volume production, Microchip Direct typically offers the best factory pricing, while distributors offer faster lead times for prototyping.
What is the price of PIC18LF4553-I/ML at qty 100?
The PIC18LF4553-I/ML is priced at approximately USD 6.40 at qty 100 as of 2026-09-28, based on distributor catalog data. Pricing drops further at qty 500 (around USD 5.75) and qty 1000 (around USD 5.10); always confirm current stock and lead time before issuing a purchase order.
What is the lead time for PIC18LF4553-I/ML?
Lead time for the PIC18LF4553-I/ML is typically 8-12 weeks from the factory and immediate from major distributors in stock tube or tape-and-reel quantities as of 2026-09-28. The device remains in active production, but USB-equipped PIC18 parts occasionally see allocation surges during industrial design refresh cycles.
PIC18LF4553-I/ML vs PIC18F4553-I/ML - which is better?
The PIC18LF4553-I/ML operates from 2.0-5.5 V with nanoWatt low-power modes, while the PIC18F4553-I/ML requires 4.2-5.5 V. For battery-powered or 3.3V USB designs, the LF variant is the correct choice; for 5V-only industrial applications, both share identical peripherals and pinouts, making them interchangeable.
What is the best drop-in replacement for PIC18LF4553-I/ML?
The PIC18F4553-I/ML is the closest drop-in replacement when 5V-only operation is acceptable. For pin-compatible flexibility the PIC18LF4550-I/ML offers the same 44-VQFN footprint and full-speed USB, with 32 KB flash. Always re-validate the device ID and pinout against the datasheet before substituting in production firmware.
When should I choose PIC18LF4553-I/ML over PIC18F4553-I/ML?
Choose PIC18LF4553-I/ML when the design must run from a battery, 3.3V rail, or any supply between 2.0 V and 5.5 V, or when nanoWatt idle/sleep modes are required to extend battery life. Choose PIC18F4553-I/ML for legacy 5V-only industrial USB peripherals where the wider LF VDD range is unnecessary.
Is PIC18LF4553-I/ML suitable for USB HID keyboard applications?
Yes, the PIC18LF4553-I/ML is well suited for USB HID keyboards, mice, and game controllers because it integrates the Full-Speed USB SIE, internal 3.3V regulator, and 12 MIPS CPU needed for HID report generation. Microchip's USB Framework provides ready-to-use HID class drivers, reducing firmware development time.
What are the key specifications of PIC18LF4553-I/ML that engineers should know?
Key specifications: 32 KB Enhanced Flash, 2048 B SRAM, 256 B EEPROM, 48 MHz / 12 MIPS throughput, 2.0-5.5 V VDD, 12-bit ADC with up to 13 channels, Full-Speed USB 2.0 with internal 3.3V regulator, I2C/SPI/USART, nanoWatt power management, and 44-VQFN industrial-grade package. These cover the PIC18F4553 datasheet family block.
Is PIC18LF4553-I/ML the same as PIC18F4553-I/ML?
No, they differ in operating voltage: PIC18LF4553-I/ML runs from 2.0-5.5 V with nanoWatt low-power features, while PIC18F4553-I/ML requires 4.2-5.5 V. Both share the same 44-VQFN (ML) package and pinout, identical peripherals, and 32 KB flash, so they are pin-compatible but not electrically interchangeable.
Where to download PIC18LF4553-I/ML datasheet PDF?
The PIC18LF4553-I/ML datasheet PDF is available from Microchip's documentation portal at microchip.com and from authorized distributors. It covers the PIC18F4553/2553/4458/2458 family with full electrical characteristics, USB chapter, ADC specifications, and package drawings for the 44-VQFN (ML) variant.
What is the best Microchip equivalent for PIC18LF4553-I/ML?
The best Microchip equivalent is PIC18LF4550-I/ML, which shares the same 44-VQFN package, USB 2.0 Full-Speed, and 32 KB flash, differing mainly in ADC channel count and specific peripheral mix. For 5V-only designs the PIC18F4553-I/ML is functionally identical with a wider legacy install base.

Engineering reference data for PIC18LF4553-I/ML — comparison, design guidance, and compliance information.

Selection Guide

Choose PIC18LF4553-I/ML when you need an 8-bit USB-capable MCU with the widest voltage tolerance (2.0-5.5 V) and nanoWatt low-power modes for battery-backed USB devices, USB HID peripherals, or portable data loggers. Choose PIC18F4553-I/ML when 5V-only operation is acceptable and you need a slightly lower-cost alternative with identical peripherals. Choose PIC18LF4550-I/ML when you want the same 44-VQFN footprint but a slightly different peripheral mix. Choose PIC18LF4455-I/ML when 24 KB flash is sufficient and you prefer to keep common firmware libraries. Choose PIC18LF4553-I/PT when hand-prototyping or manufacturing with through-hole-friendly assembly; firmware is identical across PT and ML packages.

Comparison with Alternatives

Parameter This Product PIC18F4553-I/ML PIC18LF4550-I/ML PIC18F4550-I/ML PIC18LF4455-I/ML PIC18LF4553-I/PT
Package 44-VQFN Exposed Pad (ML) 44-VQFN Exposed Pad (ML) - same 44-VQFN Exposed Pad (ML) - same 44-VQFN Exposed Pad (ML) - same 44-VQFN Exposed Pad (ML) - same 44-TQFP (PT)
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Operating Voltage 2.0 V to 5.5 V 4.2 V to 5.5 V 2.0 V to 5.5 V 4.2 V to 5.5 V 2.0 V to 5.5 V 2.0 V to 5.5 V
Program Flash 32 KB 32 KB 32 KB 32 KB 24 KB (-25%) 32 KB
RAM 2048 B 2048 B 2048 B 2048 B 2048 B 2048 B
USB 2.0 FS Yes (SIE + internal 3.3V) Yes Yes Yes Yes Yes
ADC Resolution / Channels 12-bit / 13 channels 12-bit / 13 channels 12-bit / 13 channels 12-bit / 13 channels 12-bit / 13 channels 12-bit / 13 channels
Max Clock Speed 48 MHz / 12 MIPS 48 MHz / 12 MIPS 48 MHz / 12 MIPS 48 MHz / 12 MIPS 48 MHz / 12 MIPS 48 MHz / 12 MIPS
Operating Temperature -40 C to +85 C (Industrial) -40 C to +85 C -40 C to +85 C -40 C to +85 C -40 C to +85 C -40 C to +85 C

Key Differentiators

  • Wide 2.0-5.5 V VDD range with nanoWatt low-power modes (vs PIC18F4553-I/ML)
  • Integrated USB 2.0 Full-Speed with on-chip 3.3V regulator (vs PIC18LF4458-I/ML)
  • Same silicon in QFP for easier prototyping and rework (vs PIC18LF4553-I/PT)

Design Notes

Estimated: At 48 MHz CPU clock, VDD 5.0 V, full USB peripheral set active, the PIC18LF4553-I/ML draws approximately 25 mA core current. From a 5V/500 mA USB VBUS source the internal 3.3V regulator supplies the USB transceiver, leaving ample headroom for external sensors. When running from a 3.3V rail, disable the internal regulator and tie VUSB to VDD to avoid contention. Decouple each VDD/VSS pair with 100 nF X7R placed within 5 mm of the pins to suppress switching noise.

The 44-VQFN (ML) package has an exposed thermal pad that MUST be soldered to a copper pour on the PCB (at least 1 sq inch) and tied to VSS for both thermal dissipation and ground return. Route the USB D+/D- differential pair as an 90-ohm impedance-matched pair with length matching within 2 mm. Place the 12 MHz crystal within 5 mm of OSC1/OSC2 with short, symmetric traces and a guard ground on the far side to minimize EMI susceptibility.

Do not confuse the 'F' (4.2-5.5 V) and 'LF' (2.0-5.5 V) variants - firmware will not enumerate USB below 4.2 V on F parts. The VUSB pin is the internal 3.3V regulator output in self-powered mode; it requires a 220 nF to 1 uF decoupling capacitor and must NOT be used as a load driver. The MCLR pin (RE3) is input-only on the LF4553 family - do not drive it as an output. Finally, the ICSP pins RB6/RB7 must not be pulled low at reset if in-circuit debugging is desired.

For USB Full-Speed compliance, add a 1.5 kohm pull-up on D+ (or D- for low-speed) through a soft-disconnect FET controlled by firmware, and place 27-33 ohm series resistors close to the MCU pins on each data line. The internal 3.3V regulator's stability depends on its 220 nF ceramic output capacitor with ESR below 0.5 ohm; X5R/X7R dielectrics are recommended. For noise-sensitive analog channels, place the ADC reference decoupling (100 nF + 10 uF) within 3 mm of AVDD/AVSS pins.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Unknown
Conflict Minerals
Compliant

RoHS and lead-free per Microchip product page; REACH compliance statement available on manufacturer documentation; AEC-Q100 not applicable for industrial-grade USB MCU.

Data verified on: 2026-09-28 — data verified and curated by XAIPART's component engineering team

Related Searches

PIC18LF4553-I/ML PIC18LF4553-I/ML datasheet Microchip PIC18LF4553 PIC18 USB 2.0 microcontroller 44-VQFN 44-VQFN PIC18 microcontrollers PIC18LF4553 USB HID keyboard PIC18LF4553 vs PIC18F4553 PIC18LF4553 drop-in replacement PIC18LF4553-I/ML buy price what is the operating voltage of PIC18LF4553 PIC18LF4553 pinout 44-VQFN USB microcontroller with internal 3.3V regulator

Related Components & Terms

Microchip Technology PIC18LF4553 PIC18LF4553-I/ML PIC18F4553-I/ML PIC18LF4550-I/ML PIC18LF4455-I/ML PIC18 8-bit microcontroller PIC RISC architecture USB 2.0 Full-Speed Full-Speed USB OTG 12-bit ADC nanoWatt Technology 44-VQFN VQFN Exposed Pad RoHS REACH Surface Mount MPLAB X IDE USB Framework USB HID USB CDC Industrial temperature grade Brown-out Reset ICSP
Quick Quote RFQ
Fill in complete details — our sales team will respond within 24 hours
Part Number Manufacturer Package QTY Target Price Extended
Total: $0.00 USD
✓
Quote submitted!

We will respond to your email within 24 hours

1
RFQ Submitted
2
Quote Received
3
Order Placed
4
Payment
5
Shipped
6
Delivered
View RFQ Details