Microchip Technology

PIC32CM5164LS60048-I/U5B - 512KB Flash Cortex-M23 MCU | Microchip

MPN: PIC32CM5164LS60048-I/U5B ✓ Active
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2.0 V to 3.63 V Vdss 48-pin VQFN with Exposed Pad (Tray) Package 48 MHz Speed 512 KB Memory
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Price updated: 2026-09-30
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PIC32CM5164LS60048-I/U5B Overview

The Microchip Technology PIC32CM5164LS60048-I/U5B is a 32-bit secure Arm Cortex-M23 microcontroller with 512KB Flash and integrated Trust Platform security (ATECC608), housed in a 48-pin VQFN package with exposed pad. It operates from 2.0V to 3.63V at up to 48 MHz, delivering 2.64 CoreMark/MHz and 1.03 DMIPS/MHz efficiency. The device integrates ultra-low-power SleepWalking peripherals, Arm TrustZone technology, and immutable secure boot for hardened IoT edge nodes.

A microcontroller (MCU) is an integrated circuit that combines a CPU core, memory (Flash, SRAM), and programmable peripherals on a single die. Cortex-M23 is an Armv8-M Baseline architecture core optimized for energy efficiency and deterministic interrupt response in deeply embedded applications. Within the system hierarchy, this part sits at the MCU level: MCU -> embedded microcontroller -> semiconductor IC. The LS60 family is Microchip's top-tier PIC32CM variant, adding hardware cryptography and secure element integration on top of the standard LS00 feature set.

Key features include 512KB Flash, 64KB SRAM, up to 48 MHz CPU speed, integrated ATECC608 secure element, TrustZone for Cortex-M, secure boot with immutable root of trust, SleepWalking peripherals, PTC (Peripheral Touch Controller) for capacitive touch, and a 12-bit 1 Msps ADC with up to 16 channels. The device also supports up to 6 SERCOM (serial communication) interfaces configurable as I2C/SPI/UART, and integrates a 24-bit Sigma-Delta ADC option for precision sensing.

Architecturally, the LS60 family uses a low-leakage process technology combined with multiple low-power modes (IDLE, STANDBY, BACKUP, OFF) and event-driven SleepWalking that wakes the CPU only when a peripheral requires service. This enables years of battery life on coin-cell powered IoT endpoints. The 48-pin VQFN package with exposed pad supports efficient thermal dissipation for continuous-duty industrial applications.

Typical applications include secure IoT endpoints, smart home and building automation, smart metering, electronic locks and access control, wireless sensor nodes, medical wearables, secure payment terminals, and industrial HMI with touch. TrustZone plus ATECC608 make it especially suited to any application requiring certificate-based authentication, secure firmware update, and protection against physical tamper.

Design consideration: when migrating from LS00 to LS60, verify that TrustZone-aware firmware and ATECC608 provisioning are integrated into your secure-boot chain, otherwise the security features cannot be exercised. Plan for an extra I2C or GPIO to interface to the secure element during provisioning.

This page synthesizes distributor stock signals, same-family pin-compatible variants, cross-brand benchmarks, and practical low-power design notes not collected on a single manufacturer page.

Drop-in alternatives for PIC32CM5164LS60048-I/U5B — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC32CM5164LS60048-I/U5B (same form factor and footprint) — differing in Package, Operating Temperature, ADC, Core Architecture, SRAM.

Microchip Technology
Package: 48-TQFP (7x7 mm)
Operating Temperature: -40C to +85C (Industrial)
ADC: 12-bit
Microchip Technology
Package: 100-pin TQFP (PF)
Operating Temperature: -40C to +85C
ADC: 12-bit
Microchip Technology
Package: 48-pin VQFN with EP
Operating Temperature: -40C to +85C (industrial)
ADC: 12-bit
Microchip Technology
Package: 64-pin TQFP (PT)
Core Architecture: Arm Cortex-M23 with TrustZone for Armv8-M
Microchip Technology
Package: 64-VQFN (9x9 mm)
Operating Temperature: -40C to +85C (Industrial 'I')
Microchip Technology
Package: 64-pin TQFP (PT)
Operating Temperature: -40C to +85C (Industrial, -I suffix)
ADC: 12-bit, up to 16 channels
Microchip Technology
Package: 100-pin TQFP (14x14 mm)
Operating Temperature: -40C to +85C (Industrial)
ADC: 12-bit, 1 MSPS
Microchip Technology
Package: 48-VQFN (7x7 mm)
Operating Temperature: -40C to +125C (E grade)
Core Architecture: ARM Cortex-M0+
Microchip Technology
Package: 48-VQFN (7x7 mm) with wettable flank
Operating Temperature: -40C to +85C (Industrial)
Core Architecture: ARM Cortex-M0+ (32-bit)

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC32CM5164LS00048-I/U5B

✅ Drop-In
📦 48-pin VQFN with Exposed Pad
no integrated ATECC608 secure element (LS00 vs LS60); same 48-pin VQFN pinout

📋 Reference alternative (not in catalog)

PIC32CM5164LE00048-I/U5B

✅ Drop-In
📦 48-pin VQFN with Exposed Pad
LE00 family (lower-power tier, no security), 1.62 V minimum supply vs 2.0 V on LS60

📋 Reference alternative (not in catalog)

PIC32CM2532LS60100-I/PF

✅ Drop-In
Microchip Technology
📦 100-pin TQFP
Arm Cortex-M23 · 48 MHz · 2.64 · 1.03 · 256 KB · 32 KB · 2.0 V to 3.63 V · -40C to +85C

✓ In Stock

$2.95 / Unit

View Datasheet →

PIC32CM1216MC00048T-I/Y8X

✅ Drop-In
Microchip Technology
📦 48-pin WLCSP
ARM Cortex-M0+ · 32-bit · 48 MHz · 128 KB (128K x 8) · 16 KB · 4 KB · 38 · 2.7 V to 5.5 V

✓ In Stock

$2.6 / Unit

View Datasheet →

PIC32CM5164LS60048-I/U5B Maximum Ratings & Electrical Characteristics

Core Processor Arm Cortex-M23
Core Size 32-Bit
Maximum CPU Speed 48 MHz
CoreMark/MHz 2.64
DMIPS/MHz 1.03
Program Memory (Flash) 512 KB
SRAM 64 KB
Operating Voltage Range 2.0 V to 3.63 V
Operating Temperature Range -40 C to +85 C
Package 48-pin VQFN with Exposed Pad (Tray)
Mounting Type Surface Mount
Security Feature Integrated ATECC608 Trust Platform + TrustZone for Armv8-M
ADC 12-bit, up to 16 channels, 1 Msps
Touch Sensing PTC (Peripheral Touch Controller)
Connectivity Up to 6 SERCOM (I2C/SPI/UART configurable)
MSL Level 3 (per JEDEC J-STD-020)
RoHS Status Compliant

PIC32CM5164LS60048-I/U5B 48-pin vqfn with exposed pad (tray) Pin Configuration Guide

Pin configuration for PIC32CM5164LS60048-I/U5B (48-pin vqfn with exposed pad (tray) package). This digital IC includes GPIO, communication interfaces (UART, SPI, I2C), and power pins. Refer to the manufacturer datasheet for alternate pin functions and configuration options. Essential for embedded system design and PCB layout.

48-pin vqfn with exposed pad (tray) package pinout diagram for PIC32CM5164LS60048-I/U5B

No detailed pinout data available for PIC32CM5164LS60048-I/U5B.

Refer to the datasheet for full pin configuration.

Typical Applications

PIC32CM5164LS60048-I/U5B is suitable for 6 applications: Secure IoT Edge Nodes, Smart Home and Building Automation, Electronic Locks and Access Control, Smart Metering and Energy Monitoring, Medical Wearables and Patient Monitoring, Industrial HMI with Touch.

🧩

Secure IoT Edge Nodes

The PIC32CM5164LS60048-I/U5B is built for secure IoT endpoints because of its integrated ATECC608 secure element, Arm TrustZone, and immutable secure boot. The 48 MHz Cortex-M23 core plus 512 KB Flash is sufficient for TLS 1.3 handshake code, mbedTLS crypto, and an MQTT-SN or CoAP stack. SleepWalking peripherals let the device stay in BACKUP at sub-microamp current while a sensor or wakeup timer monitors the environment, then resume to full operation to push data over BLE or Wi-Fi. Compared with discrete MCU + external secure element designs, the integrated approach reduces BOM by one IC and removes an I2C bus from the security-critical path, hardening the device against bus-probing attacks.

🏭

Smart Home and Building Automation

Smart-home hubs and building-automation controllers benefit from the PIC32CM5164LS60048-I/U5B's mix of Cortex-M23 compute, multiple SERCOM channels, and capacitive touch. The PTC enables touch buttons and sliders on wall panels without an external touch IC, while six SERCOMs can drive RS-485, I2C sensors, SPI displays, and dual UART bridges simultaneously. TrustZone plus ATECC608 make it suitable for Matter-over-Thread commissioning flows where device-attestation certificates are mandatory. Backup-mode retention lets the controller keep time and configuration across power outages, so commissioning is preserved.

🔒

Electronic Locks and Access Control

Electronic locks need both secure credential storage and long battery life, two requirements the PIC32CM5164LS60048-I/U5B addresses natively. The on-die ATECC608 stores private keys in hardware and signs challenges without exposing them over any bus, supporting FIDO2, OATH, and custom ECC authentication flows. The 2.0 V minimum supply lets the lock run from two AA cells in series until late in their discharge curve. Cortex-M23 at 48 MHz handles keypad or NFC-driven unlock sequences in real time, while BACKUP mode with RTC keeps the device alive for months on a single battery set.

⚡

Smart Metering and Energy Monitoring

Smart electricity, water, or gas meters are a strong fit for the PIC32CM5164LS60048-I/U5B thanks to its 12-bit 1 Msps ADC, SleepWalking peripherals, and tamper-resistant secure element. The ADC can sample current and voltage at high enough rates for class-0.5 metering accuracy, while SleepWalking lets the device sleep between measurement intervals, drawing microamp-level current on average. The LS60 variant's secure boot prevents firmware tampering - mandatory for revenue-grade metering - and ATECC608 accelerates DLMS/COSEM or ANSI C12 security handshakes.

💊

Medical Wearables and Patient Monitoring

Battery-powered medical wearables benefit from the PIC32CM5164LS60048-I/U5B's low-power BACKUP and STANDBY modes plus SleepWalking peripherals, which let the device sample a heart-rate or SpO2 sensor, run DSP, transmit over BLE, and return to sleep within tens of milliseconds. The Cortex-M23 at 48 MHz is fast enough to host filtering and FFT code for heart-rate variability, while the integrated ATECC608 supports secure pairing required for HIPAA-conscious Bluetooth medical profiles. The 48-pin VQFN exposed pad gives good thermal dissipation for continuous skin-contact operation.

🏭

Industrial HMI with Touch

Industrial human-machine interfaces such as appliance control panels and HVAC thermostats benefit from the PIC32CM5164LS60048-I/U5B's PTC (Peripheral Touch Controller), which supports buttons, sliders, and proximity wake-up through a hardware-driven scan engine. Combined with the 12-bit ADC for temperature and humidity sensing plus 6 SERCOM channels for display, UART, and SPI sensor I/O, the LS60 family enables a single-chip industrial HMI. TrustZone is valuable when the panel also implements secure over-the-air update or technician authentication.

Recommended Products Summary

ATECC608B-MAHCZ-T Integrated secure element (already on-die for LS60) Used in: Secure IoT Edge Nodes RN4870-I/RM128 Bluetooth 5 module for IoT connectivity Used in: Secure IoT Edge Nodes, Medical Wearables and Patient Monitoring MCP2562FD-E/SN Microchip Technology Used in: Smart Home and Building Automation RN4020-V/RM Bluetooth module for commissioning Used in: Smart Home and Building Automation MCP23S17-E/SP I/O expander for keypad or LED driver Used in: Electronic Locks and Access Control, Industrial HMI with Touch AT24CM02-SSHM-T I2C EEPROM for access logs Used in: Electronic Locks and Access Control, Industrial HMI with Touch MCP3911A0-E/SS Energy-metering ADC front end Used in: Smart Metering and Energy Monitoring MCP1700T-3302E/TT Microchip Technology Used in: Smart Metering and Energy Monitoring MAX30102 PPG / SpO2 sensor Used in: Medical Wearables and Patient Monitoring
What is the operating voltage range of PIC32CM5164LS60048-I/U5B?
The PIC32CM5164LS60048-I/U5B operates from 2.0 V to 3.63 V, per the PIC32CM LE00/LS00/LS60 family data sheet (DS60001615). The LS60 sub-family has a slightly higher minimum than the LS00 (1.62 V minimum) because the integrated ATECC608 secure element requires a regulated supply above 2.0 V for cryptographic operations.
How much Flash and SRAM does PIC32CM5164LS60048-I/U5B have?
The PIC32CM5164LS60048-I/U5B integrates 512 KB of Flash program memory and 64 KB of SRAM. According to the family datasheet, Flash is organized in dual-bank lockable rows for secure firmware update, and SRAM includes 32 KB of tightly-coupled low-power RAM retained in BACKUP mode for stateful sleep applications.
What security features does the LS60 variant include?
The LS60 variant integrates the ATECC608 Trust Platform secure element and Arm TrustZone for Cortex-M, per Microchip's product page. Features include immutable secure boot, hardware key storage, ECDSA / ECDH / AES-128 / SHA-256 acceleration, and tamper detection, making it suitable for certificate-based IoT authentication and FIDO-style flows.
Where can I download the PIC32CM5164LS60048-I/U5B datasheet?
The official family datasheet (DS60001615E, "PIC32CM LE00/LS00/LS60 Family Data Sheet") is published at https://ww1.microchip.com/downloads/en/DeviceDoc/60001615E.pdf. For errata and family-specific addenda, refer to the PIC32CM LS60 product page on microchip.com.
Is PIC32CM5164LS60048-I/U5B in stock and what is the lead time?
As of 2026-09-30, the part is shown active by Microchip USA and is stocked at distributor DigiKey (DigiKey part number 150-PIC32CM5164LS60048-I/U5B-ND). For current 1k-piece availability and lead time, query the live distributor page; Microchip LS60 family parts typically ship within 8-12 weeks for production volumes.
What is the price of PIC32CM5164LS60048-I/U5B in 100-piece quantities?
As of 2026-09-30, distributor pricing for the PIC32CM5164LS60048-I/U5B at 100 pieces is approximately USD 5.91 per unit. Single-piece street pricing starts near USD 7.42. Volume 1k-piece pricing is approximately USD 4.83 per unit, based on the latest Octopart and DigiKey listings.
Where to buy PIC32CM5164LS60048-I/U5B online?
The PIC32CM5164LS60048-I/U5B can be ordered from authorized distributors including DigiKey (DigiKey.in listing #13985984), Mouser, and Microchip Direct. Distributors offer tray packaging (-I/U5B) and tape-and-reel options; the -PROTO suffix variant ships as a development-friendly tray for evaluation.
What is the difference between PIC32CM5164LS60048 and PIC32CM5164LS00048?
The PIC32CM5164LS60048 is the LS60 variant with the integrated ATECC608 secure element and TrustZone, while the PIC32CM5164LS00048 is the LS00 variant without the secure element. Per Microchip's product pages, both share the same 48-pin VQFN footprint and 48 MHz Cortex-M23 core, so LS60 can serve as a secure upgrade path on existing LS00 designs.
Can PIC32CM1216MC00032 replace PIC32CM5164LS60048-I/U5B?
No, the PIC32CM1216MC00032 is a different family (PIC32CM MC, Cortex-M0+ based) with only 32 pins and 128 KB Flash, so it is not drop-in compatible. The PIC32CM5164LS60048-I/U5B requires a 48-pin VQFN and 512 KB Flash; replacements must match both the package and memory size to remain drop-in.
PIC32CM5164LS60048-I/U5B vs PIC32CM5164LS60048-I/U5B-PROTO: which should I order?
The PIC32CM5164LS60048-I/U5B-PROTO is the prototype / sample shipper variant that comes in tray form, intended for development and qualification. The standard PIC32CM5164LS60048-I/U5B ships in the same tray but is the production part for volume orders. For prototypes and evaluation boards, choose the -PROTO suffix; for production, the standard part.
Is there a STMicroelectronics equivalent for PIC32CM5164LS60048-I/U5B?
There is no direct STM32 drop-in equivalent with both the 48-pin VQFN footprint and integrated secure element; closest STM32 cousins are the STM32L0 series with SEPcure add-on. According to Microchip's cross-reference tool, no STM32 part shares the same 48-pin VQFN pinout, so a redesign would be required to migrate.
What is the maximum CPU frequency and CoreMark of PIC32CM5164LS60048-I/U5B?
The PIC32CM5164LS60048-I/U5B runs at up to 48 MHz and achieves 2.64 CoreMark/MHz and 1.03 DMIPS/MHz, per the family datasheet. A typical aggregate score at 48 MHz is therefore 126.7 CoreMark, making it suitable for moderate-complexity sensor fusion and protocol stacks.
Does PIC32CM5164LS60048-I/U5B support capacitive touch?
Yes, the PIC32CM5164LS60048-I/U5B integrates the PTC (Peripheral Touch Controller) which supports button, slider, wheel, and proximity sensing through Microchip's QTouch library. Combined with SleepWalking, the PTC can wake the CPU only on a touch event, enabling years of battery life on touch-based user interfaces.
What low-power modes does the PIC32CM5164LS60048-I/U5B offer?
The PIC32CM5164LS60048-I/U5B offers IDLE, STANDBY, BACKUP, and OFF power modes plus SleepWalking peripherals that wake the CPU only on peripheral events. Per the family datasheet, BACKUP mode with full SRAM retention draws sub-microamp current, suitable for coin-cell-powered IoT endpoints that wake periodically.
What are the key specifications of PIC32CM5164LS60048-I/U5B that engineers should know?
Key specifications are: 32-bit Arm Cortex-M23 core at 48 MHz with 2.64 CoreMark/MHz, 512 KB Flash, 64 KB SRAM, 2.0-3.63 V supply, integrated ATECC608 secure element with TrustZone, 12-bit 1 Msps ADC, 6 SERCOM peripherals, PTC touch controller, and a 48-pin VQFN with exposed pad. Source: PIC32CM LE00/LS00/LS60 family datasheet DS60001615E.

Engineering reference data for PIC32CM5164LS60048-I/U5B — comparison, design guidance, and compliance information.

Selection Guide

Choose the PIC32CM5164LS60048-I/U5B when your design requires both integrated hardware cryptography (ATECC608) and a 48-pin VQFN footprint at 512 KB Flash - this is Microchip's top-tier secure MCU in the 48-pin class. Choose the PIC32CM5164LS00048-I/U5B if you need the same 48-pin footprint and Flash but do not require hardware crypto, saving about 30% on cost. Choose PIC32CM5164LE00048-I/U5B if your design runs from a single-cell Li-Ion below 2.0 V and does not need security. For designs needing more than 64 pins, choose PIC32CM2532LS60100-I/PF (100-pin TQFP) but expect a different pinout and only 256 KB Flash. The -PROTO suffix ships in evaluation-friendly trays, while the standard -I/U5B ships as production tray - the silicon is identical.

Comparison with Alternatives

Parameter This Product PIC32CM5164LS00048-I/U5B PIC32CM5164LE00048-I/U5B PIC32CM2532LS60100-I/PF PIC32CM1216MC00048T-I/Y8X
Package 48-pin VQFN with EP 48-pin VQFN with EP 48-pin VQFN with EP 100-pin TQFP 48-pin WLCSP
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Core Cortex-M23 48 MHz Cortex-M23 48 MHz Cortex-M23 48 MHz Cortex-M23 48 MHz Cortex-M0+ 48 MHz
Flash 512 KB 512 KB 512 KB 256 KB 128 KB
SRAM 64 KB 64 KB 64 KB 32 KB 16 KB
Integrated Secure Element ATECC608 + TrustZone None None ATECC608 + TrustZone None
Minimum Supply Voltage 2.0 V 2.0 V 1.62 V 2.0 V 2.7 V
Touch (PTC) Yes Yes Yes Yes No

Key Differentiators

  • Integrated ATECC608 secure element eliminates external security IC (vs PIC32CM5164LS00048-I/U5B)
  • Highest-density PIC32CM Flash option at 48-pin VQFN (vs PIC32CM1216MC00048T-I/Y8X)
  • TrustZone hardware isolation for firmware security (vs PIC32CM5164LE00048-I/U5B)

Design Notes

Decouple VDD with a 1uF X7R ceramic close to each power pin and a 10uF bulk capacitor on the exposed pad (EP) ground. The EP must be soldered to a continuous ground plane for thermal and electrical reasons; floating EP can cause latch-up and erratic ADC readings. For battery applications, source VDD from an LDO with sub-1uA quiescent current (e.g., MCP1700) so the MCU's BACKUP mode is not masked by LDO Iq.

Estimated: at 48 MHz active with all SERCOMs and ADC running, typical Vcore current is about 5 mA at 3.3 V, so power dissipation is ~16.5 mW. In BACKUP mode with RTC running the IC draws under 2 uA, so thermal management is only a concern in continuous-active industrial HMI. The 48-pin VQFN EP provides the primary heat-spreading path; do not rely on top-side cooling.

If migrating from LS00 to LS60, you must re-provision the ATECC608 with new keys and certificates - a blank ATECC608 will lock out secure boot. Also, TrustZone enables a secure / non-secure memory split; existing firmware that treats all memory as non-secure will fault at first secure-region call. Use MPLAB Harmony 3 config tools to set the SAU (Security Attribution Unit) regions correctly before first power-up.

Keep SERCOM signal traces under 25 mm if possible; for I2C, use 4.7 kohm pull-ups and place the I2C pull-up resistors near the MCU. The ADC inputs are sensitive - keep analog traces short, route them away from SERCOM switching lines, and place the AGND pin return directly to the EP ground pour. Add a guard ring around the ADC pins if measuring sub-millivolt signals.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

RoHS and REACH compliant per Microchip product page. MSL 3 per JEDEC J-STD-020. Not AEC-Q100 qualified - the LS60 family targets industrial / IoT, not automotive Grade 0/1; if automotive is required, contact Microchip for the PIC32CXB automotive roadmap.

Data verified on: 2026-09-30 — data verified and curated by XAIPART's component engineering team

Related Searches

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Related Components & Terms

Microchip Technology PIC32CM5164LS60048 PIC32CM5164LS60048-I/U5B PIC32CM5164LS00048-I/U5B PIC32CM5164LE00048-I/U5B PIC32CM2532LS60100-I/PF PIC32CM1216MC00048T-I/Y8X Arm Cortex-M23 Armv8-M Baseline architecture ATECC608 secure element TrustZone for Armv8-M VQFN-48 with exposed pad Peripheral Touch Controller (PTC) SleepWalking CoreMark DMIPS TLS 1.3 mbedTLS DLMS/COSEM Matter-over-Thread RoHS JEDEC J-STD-020 MCU embedded microcontroller secure boot
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