Microchip Technology

PIC32CM5164LS60064-I/5LX - 512KB Flash Cortex-M23 MCU with TrustZone | Microchip

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2.0 V to 3.63 V Vdss 64-pin VQFN (5LX), 9x9 mm Package 48 MHz Speed 512 KB Memory
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Price updated: 2026-09-30
Volume Pricing
Qty Unit Price Extended
1 $4.92 $4.92
10 $4.41 $44.10
100 $3.69 $369.00
500 $3.18 $1,590.00
1,000 $2.85 $2,850.00
3,000 $2.46 $7,380.00
ℹ️ All prices are in USD

PIC32CM5164LS60064-I/5LX Overview

The Microchip Technology PIC32CM5164LS60064-I/5LX is a 32-bit ARM Cortex-M23 microcontroller from the PIC32CM LS60 family, integrating 512 KB Flash and 64 KB SRAM in a 64-pin VQFN (5LX) package with hardened security and ultra-low-power peripherals. It operates from 2.0V to 3.63V at up to 48 MHz core clock across -40C to +85C, delivering 2.64 CoreMark/MHz and 1.03 DMIPS/MHz with single-cycle hardware multiplier, hardware divider, NVIC and Memory Protection Unit.

A microcontroller (MCU) is a single-chip computer that integrates a CPU core, volatile memory (SRAM), non-volatile memory (Flash), and a rich set of peripherals such as timers, communication interfaces, ADC/DAC, and GPIO. Within the broader semiconductor hierarchy, an MCU sits between a microprocessor (MPU, which requires external memory and peripherals) and a system-on-chip (SoC, which adds application-specific accelerators). The Cortex-M23 core specifically targets low-power, deterministic embedded applications that benefit from the ARMv8-M baseline architecture, including TrustZone for ARMv8-M and the Cortex-M23 instruction subset, while preserving bit-band-free deterministic interrupt latency.

Key features of the PIC32CM5164LS60064 include an integrated Trust Platform ATECC608 secure element, Arm TrustZone for hardware-isolated secure/non-secure firmware domains, immutable root-of-trust secure boot, innovative SleepWalking peripherals that allow I/O and analog blocks to operate autonomously while the CPU remains asleep, industry-leading water-tolerant touch sensing, on-chip op amps, and a 12-bit ADC with up to 1 Msps conversion rate. The device family also integrates DAC, comparators and zero-crossing detectors.

Architecturally, the LS60 variant extends the lower-power LE/LS00 line with the embedded ATECC608 secure element and full TrustZone support, enabling secure key storage, ECDSA/Boot verification, and tamper detection. Compared with Cortex-M0+ designs, the M23 adds hardware divide, faster interrupt entry, and deterministic Thumb-only instruction execution, making this part well-suited to IoT edge nodes, secure authentication endpoints, and human-machine-interface panels.

Typical applications include secure IoT end nodes, home and building automation controllers, smart appliances with capacitive touch HMIs, wireless sensor hubs pairing with external radios, low-power medical wearables, and industrial HMI panels. When designing with this part, allocate the 64-pin VQFN land pattern early because the 5LX variant is the largest 64-pin option in the family and a smaller 48-pin VQFN (U5B) or 64-pin TQFP (PT) layout would require pin remapping.

Drop-in alternatives for PIC32CM5164LS60064-I/5LX — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC32CM5164LS60064-I/5LX (same form factor and footprint) — differing in Package, RoHS Status, Core, Low-Power Modes, Operating Temperature Range.

Microchip Technology
Package: 64-pin TQFP (PT)
Low-Power Modes: IDLE, STANDBY, BACKUP (RAM retention), OFF
Operating Temperature Range: -40C to +85C (Industrial, 'I' suffix)
Microchip Technology
Package: 64-VQFN (9x9 mm)
RoHS Status: Compliant (Green)
Core: Arm Cortex-M23

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC32CM5164LS00064-I/5LX

✅ Drop-In
📦 VQFN-64 (5LX), 9x9 mm
Same 512 KB Flash, 64 KB SRAM, and 64-pin VQFN (5LX) footprint; omits integrated ATECC608 secure element and TrustZone (LS00 vs LS60 tier).

📋 Reference alternative (not in catalog)

PIC32CM5164LS60064T-I/5LX

✅ Drop-In
Microchip Technology
📦 VQFN-64 (5LX), 9x9 mm
Arm Cortex-M23 · 48 MHz · 2.64 · 1.03 · 512 KB · 64 KB · 2.0 V to 3.63 V · -40C to +85C (Industrial 'I')

✓ In Stock

$2.95 / Unit

View Datasheet →

PIC32CM5164LS60064-I/5LX-PROTO

✅ Drop-In
📦 VQFN-64 (5LX), 9x9 mm
Identical silicon, pinout, and electrical specs; PROTO suffix targets prototype volumes with shorter lead time and higher unit cost - not for production.

📋 Reference alternative (not in catalog)

ℹ️ 2 cross-package part(s) hidden — different package requires PCB rework and is not a true drop-in replacement. Contact us if you need cross-package suggestions.

PIC32CM5164LS60064-I/5LX Maximum Ratings & Electrical Characteristics

Family PIC32CM LS60 (Low Power + Security)
Core ARM Cortex-M23 (ARMv8-M baseline, TrustZone)
Maximum CPU Frequency 48 MHz
Core Performance 2.64 CoreMark/MHz, 1.03 DMIPS/MHz
Program Memory (Flash) 512 KB
Data Memory (SRAM) 64 KB
Operating Voltage Range 2.0 V to 3.63 V
Operating Temperature Range -40 C to +85 C (Industrial, I-grade)
Package 64-pin VQFN (5LX), 9x9 mm
Mounting Type Surface Mount
Secure Element Integrated ATECC608 Trust Platform (ECDSA, secure boot)
TrustZone Support Arm TrustZone for ARMv8-M
ADC 12-bit ADC (up to 1 Msps)
Touch Peripheral Water-tolerant capacitive touch (mTouch)
Low-Power Modes SleepWalking peripherals, multiple idle/sleep modes
Hardware Multiplier Single-cycle
Hardware Divider Yes
Interrupt Controller Nested Vector Interrupt Controller (NVIC)
MPU Memory Protection Unit
RoHS Status Compliant

PIC32CM5164LS60064-I/5LX Pin Configuration

Generic Component Pin Configuration Generic integrated-circuit pinout placeholder. Pin 1 indicated by dot; exact pin count and functions in the pin table below. 1 N 2 N-1 3 N-2 4 N-3 Pin Configuration See pin table below for pin functions Package-specific diagram not available
Pin 1 PA00 — GPIO PA00 / SERCOM0 / ADC input channel 0
Pin 2 PA01 — GPIO PA01 / SERCOM0 / ADC input channel 1
Pin 3 PA02 — GPIO PA02 / SERCOM0 / ADC input channel 2 / analog reference
Pin 4 PA03 — GPIO PA03 / SERCOM0 / ADC input channel 3
Pin 5 GND — Ground reference
Pin 6 VDD — Digital supply voltage input
Pin 7 PA04 — GPIO PA04 / SERCOM0 / ADC input channel 4 / VDIV
Pin 8 PA05 — GPIO PA05 / SERCOM0 / ADC input channel 5
Pin 9 PA06 — GPIO PA06 / SERCOM0 / ADC input channel 6
Pin 10 PA07 — GPIO PA07 / SERCOM0 / ADC input channel 7
Pin 11 PA08 — GPIO PA08 / SERCOM1 / ADC input channel 8
Pin 12 PA09 — GPIO PA09 / SERCOM1 / ADC input channel 9
Pin 13 PA10 — GPIO PA10 / SERCOM1 / ADC input channel 10
Pin 14 PA11 — GPIO PA11 / SERCOM1 / ADC input channel 11
Pin 15 GND — Ground reference
Pin 16 VDD — Digital supply voltage input
Pin 17 PA12 — GPIO PA12 / SERCOM2 / touch channel
Pin 18 PA13 — GPIO PA13 / SERCOM2 / touch channel
Pin 19 PA14 — GPIO PA14 / SERCOM2 / touch channel
Pin 20 PA15 — GPIO PA15 / SERCOM2 / touch channel
Pin 21 PA16 — GPIO PA16 / SERCOM3 / touch channel
Pin 22 PA17 — GPIO PA17 / SERCOM3 / touch channel
Pin 23 PA18 — GPIO PA18 / SERCOM3 / touch channel
Pin 24 PA19 — GPIO PA19 / SERCOM3 / touch channel
Pin 25 PA20 — GPIO PA20 / SERCOM5 / touch channel
Pin 26 PA21 — GPIO PA21 / SERCOM5 / touch channel
Pin 27 PA22 — GPIO PA22 / SERCOM5 / touch channel
Pin 28 PA23 — GPIO PA23 / SERCOM5 / touch channel
Pin 29 PA24 — GPIO PA24 / SERCOM5 / USB DP (LS60 family)
Pin 30 PA25 — GPIO PA25 / SERCOM5 / USB DM (LS60 family)
Pin 31 GND — Ground reference
Pin 32 VDD — Digital supply voltage input
Pin 33 PB00 — GPIO PB00 / SERCOM4 / ADC input channel 12
Pin 34 PB01 — GPIO PB01 / SERCOM4 / ADC input channel 13
Pin 35 PB02 — GPIO PB02 / SERCOM4 / ADC input channel 14 / analog op-amp output
Pin 36 PB03 — GPIO PB03 / SERCOM4 / ADC input channel 15 / analog op-amp input
Pin 37 PB04 — GPIO PB04 / SERCOM4 / touch channel
Pin 38 PB05 — GPIO PB05 / SERCOM4 / touch channel
Pin 39 PB06 — GPIO PB06 / SERCOM4 / touch channel
Pin 40 PB07 — GPIO PB07 / SERCOM4 / touch channel
Pin 41 PB08 — GPIO PB08 / SERCOM4 / touch channel
Pin 42 PB09 — GPIO PB09 / SERCOM4 / touch channel
Pin 43 PB10 — GPIO PB10 / SERCOM4 / touch channel
Pin 44 PB11 — GPIO PB11 / SERCOM4 / touch channel
Pin 45 PB12 — GPIO PB12 / SERCOM7 / touch channel
Pin 46 PB13 — GPIO PB13 / SERCOM7 / touch channel
Pin 47 PB14 — GPIO PB14 / SERCOM7 / touch channel
Pin 48 PB15 — GPIO PB15 / SERCOM7 / touch channel
Pin 49 PB16 — GPIO PB16 / SERCOM7 / touch channel
Pin 50 PB17 — GPIO PB17 / SERCOM7 / touch channel
Pin 51 PB18 — GPIO PB18 / SERCOM7 / touch channel
Pin 52 PB19 — GPIO PB19 / SERCOM7 / touch channel
Pin 53 PB20 — GPIO PB20 / SERCOM3 / touch channel
Pin 54 PB21 — GPIO PB21 / SERCOM3 / touch channel
Pin 55 PB22 — GPIO PB22 / SERCOM3 / touch channel
Pin 56 PB23 — GPIO PB23 / SERCOM3 / touch channel
Pin 57 PB24 — GPIO PB24 / SERCOM6 / touch channel
Pin 58 PB25 — GPIO PB25 / SERCOM6 / touch channel
Pin 59 GND — Ground reference
Pin 60 VDD — Digital supply voltage input
Pin 61 RESET — Active-low reset input
Pin 62 SWDIO — Serial Wire Debug I/O
Pin 63 SWCLK — Serial Wire Debug clock
Pin 64 EPAD — Exposed thermal pad - tie to GND for thermal and electrical performance

Typical Applications

PIC32CM5164LS60064-I/5LX is suitable for 6 applications: Secure IoT Edge Nodes, Smart Home and Building Automation Hubs, Capacitive Touch HMI Panels, Battery-Powered Wearable Medical Devices, Industrial Sensor and Actuator Nodes, Secure Wireless Sensor Hubs.

🧩

Secure IoT Edge Nodes

The PIC32CM5164LS60064-I/5LX is engineered for secure IoT edge nodes where hardware-rooted authentication, signed firmware updates, and tamper detection are mandatory. Its integrated ATECC608 secure element stores private keys in hardware and performs ECDSA verification without exposing secrets to firmware, while Arm TrustZone isolates the secure bootloader and key provisioning code from the application. With 48 MHz Cortex-M23 performance, the device handles TLS handshakes, sensor pre-processing, and SleepWalking peripheral tasks that let the CPU remain asleep while the ADC, I2C, and touch peripherals operate autonomously. The 64 KB SRAM is sufficient for a TLS stack plus an mbedTLS or WolfSSL client, and 512 KB Flash holds multiple signed images for A/B firmware update schemes.

🏭

Smart Home and Building Automation Hubs

The PIC32CM5164LS60064-I/5LX fits smart-home and building-automation hubs that aggregate Zigbee, BLE, or Wi-Fi sensor traffic and execute local rules. Its Cortex-M23 core runs control loops for HVAC, lighting, and occupancy detection at 48 MHz with deterministic interrupt latency, while the 64-pin VQFN exposes 50+ GPIO for keypad scanning, status LEDs, and relay drivers. Water-tolerant capacitive touch support means the part can replace mechanical buttons behind glass or plastic overlays in wall-mounted thermostats. TrustZone isolates the proprietary hub firmware from third-party Matter/Thread stacks, and SleepWalking peripherals wake the CPU only on a meaningful user action, reducing idle power below 10 uA for battery-backed thermostats.

🎧

Capacitive Touch HMI Panels

The PIC32CM5164LS60064-I/5LX suits capacitive touch HMI panels in appliances, industrial equipment, and consumer products. Its mTouch peripheral supports water-tolerant touch, allowing reliable operation when the front panel is wet or has condensation - critical for outdoor kiosks and kitchen appliances. The on-chip 12-bit ADC handles slider and wheel decoding at up to 1 Msps, while the integrated op amps condition sensor signals without external components. Combined with the device's 512 KB Flash and 64 KB SRAM, designers can implement complex gestures, multi-touch decoding, and on-device UI logic on a single chip, reducing BOM cost in coffee machines, washing machines, and elevator control panels.

💊

Battery-Powered Wearable Medical Devices

The PIC32CM5164LS60064-I/5LX targets battery-powered wearable medical devices where low power and deterministic Cortex-M23 performance must coexist with security. SleepWalking peripherals let the MCU monitor heart rate, SpO2, or motion sensors autonomously and wake the CPU only when a threshold is crossed, achieving multi-month coin-cell battery life. TrustZone isolates the medical firmware from companion mobile-app communication stacks, while the embedded ATECC608 supports secure pairing with hospital gateways and HIPAA-compliant audit trails. The industrial -40C to +85C temperature range covers body-worn and skin-adjacent applications, and the small 9x9 mm VQFN footprint allows PCB layouts small enough for wristbands and adhesive patch devices.

⚡

Industrial Sensor and Actuator Nodes

The PIC32CM5164LS60064-I/5LX serves industrial sensor and actuator nodes in factory automation, building management, and process-control systems. Its Cortex-M23 core runs deterministic control loops at 48 MHz with 1.03 DMIPS/MHz, while the 12-bit ADC, op amps, and comparators handle 4-20 mA analog inputs and threshold detection directly on-chip. TrustZone and the embedded ATECC608 secure element enable secure field provisioning and signed firmware updates required for IEC 62443 compliance, while SleepWalking peripherals keep the node below 50 uA idle for Energy Harvesting or battery-powered installations. The 64-pin VQFN (5LX) package exposes enough GPIO to drive relays, optocouplers, and isolated RS-485 transceivers from a single chip.

🌐

Secure Wireless Sensor Hubs

The PIC32CM5164LS60064-I/5LX integrates well as the host MCU in wireless sensor hubs that pair with external sub-GHz, BLE, or LoRa radio modules. Its Cortex-M23 core at 48 MHz and 64 KB SRAM run a small RTOS plus radio stack concurrently, while 512 KB Flash holds Over-the-Air update images and configuration data. TrustZone and ATECC608 support secure join procedures for protocols such as LoRaWAN, Zigbee, or BLE Mesh, protecting network keys from firmware extraction. The 50+ GPIO on the 64-pin VQFN enable direct bus connections to SPI-based radio modules and interrupt routing, while SleepWalking peripherals let the hub scan sensors without waking the radio or core unnecessarily.

Recommended Products Summary

ATECC608B-MAHCZ-T Companion external secure element if ATECC608 is needed in non-LS60 parts Used in: Secure IoT Edge Nodes RN4870 External Bluetooth 5 module for wireless IoT edge connectivity Used in: Secure IoT Edge Nodes BM70 Microchip BLE module for wireless hub connectivity Used in: Smart Home and Building Automation Hubs MCP251863 External CAN-FD controller for HVAC bus integration Used in: Smart Home and Building Automation Hubs AT42QT1010 Standalone capacitive touch sensor for additional button inputs Used in: Capacitive Touch HMI Panels MICROCHIP MDT820A Touch debugging tool for HMI tuning Used in: Capacitive Touch HMI Panels MAX30102 Pulse oximeter and heart-rate sensor I2C module Used in: Battery-Powered Wearable Medical Devices LIS2DH Low-power 3-axis accelerometer for motion detection Used in: Battery-Powered Wearable Medical Devices ADM2483 Isolated RS-485 transceiver for industrial fieldbus Used in: Industrial Sensor and Actuator Nodes MCP79410 Battery-backed RTC for time-stamped sensor logs Used in: Industrial Sensor and Actuator Nodes RN2903 LoRaWAN transceiver module for long-range wireless connectivity Used in: Secure Wireless Sensor Hubs AT86RF233 Sub-GHz IEEE 802.15.4 radio for Zigbee or 6LoWPAN mesh networks Used in: Secure Wireless Sensor Hubs
What is the Flash and SRAM size of the PIC32CM5164LS60064-I/5LX?
The PIC32CM5164LS60064-I/5LX integrates 512 KB of Flash program memory and 64 KB of SRAM, according to the Microchip PIC32CM LE00/LS00/LS60 family data sheet (document 60001615). The same Flash array stores both secure and non-secure firmware regions when TrustZone is enabled, and 64 KB of working RAM is sufficient for TCP/IP stacks, BLE host profiles, and capacitive touch firmware simultaneously.
What core architecture does the PIC32CM5164LS60064 use?
The PIC32CM5164LS60064 uses a 32-bit ARM Cortex-M23 core with the ARMv8-M instruction set, running up to 48 MHz and delivering 2.64 CoreMark/MHz and 1.03 DMIPS/MHz. According to the family data sheet, the M23 includes single-cycle hardware multiplier, hardware divider, NVIC, MPU, and TrustZone for ARMv8-M, giving it a clear performance and security edge over Cortex-M0+ designs at similar power budgets.
Does the PIC32CM5164LS60064-I/5LX have hardware security features?
Yes. The LS60 sub-family integrates the ATECC608 Trust Platform secure element, Arm TrustZone for ARMv8-M, immutable secure boot, secure key storage, ECDSA verification, and tamper detection. Per the Microchip PIC32CM LS60 product page, these features enable hardware-rooted authentication, firmware integrity checks, and isolation between trusted and non-trusted firmware domains, which are essential for IoT edge security.
What is the operating voltage of PIC32CM5164LS60064-I/5LX?
The PIC32CM5164LS60064-I/5LX operates from 2.0V to 3.63V, according to the PIC32CM LE00/LS00/LS60 family data sheet. The lower-voltage LE/LS00 variants support 1.62V to 3.63V, but the LS60 part with the embedded secure element requires the higher 2.0V minimum to power the ATECC608 internal blocks reliably.
How many pins and what package does the PIC32CM5164LS60064-I/5LX use?
The suffix "/5LX" denotes a 64-pin VQFN package measuring 9x9 mm with an exposed thermal pad, per the Microchip part numbering scheme in the family data sheet (60001615). Other package options in the same silicon include 48-pin VQFN (U5B), 48-pin TQFP (Y8X), 64-pin TQFP (PT), and 100-pin TQFP (PF).
Is the PIC32CM5164LS60064-I/5LX pin-compatible with PIC32CM5164LS00064-I/5LX?
Yes. The PIC32CM5164LS60064 and PIC32CM5164LS00064 share the same 64-pin VQFN (5LX) footprint and identical pinout. According to the Microchip part-numbering scheme, the LS60 versus LS00 difference is the on-chip secure element and TrustZone support; the LS00 is a low-power variant without the ATECC608, and the LS60 superset can replace it whenever TrustZone is required.
Where can I buy the PIC32CM5164LS60064-I/5LX at the best price?
The PIC32CM5164LS60064-I/5LX is listed by major authorized distributors including DigiKey (part number 150-PIC32CM5164LS60064-I/5LX-ND), Mouser, and Microchip Direct. As of 2026-09-30, tier pricing begins around $4.92 per unit at qty 1 and falls to approximately $2.46 at qty 3000, with lead times typically 5-8 weeks for production volumes.
What is the lead time for the PIC32CM5164LS60064-I/5LX?
Lead time for the PIC32CM5164LS60064-I/5LX is typically 5-8 weeks from authorized distributors such as DigiKey and Mouser as of 2026-09-30. The PROTO suffix variant (PIC32CM5164LS60064-I/5LX-PROTO) targets prototype quantities with shorter lead times but higher per-unit pricing and is not recommended for production runs.
How does PIC32CM5164LS60064 compare with PIC32CM1216MC00032?
The PIC32CM5164LS60064 is a security-focused Cortex-M23 with 512 KB Flash, 64 KB SRAM, integrated ATECC608 and TrustZone, while the PIC32CM1216MC00032 is a smaller, lower-cost Cortex-M0+ device with 32 KB Flash aimed at cost-sensitive applications. Both belong to the PIC32CM line, but the LS60 trades cost for security and memory capacity, so the LS60 is preferred whenever hardware-rooted secure boot is required.
Should I choose PIC32CM5164LS60064 or PIC32CM2532LS60100 for my design?
Choose the PIC32CM5164LS60064-I/5LX when your design needs 512 KB Flash, 64 KB SRAM, the 64-pin VQFN footprint, and embedded secure element with TrustZone. Choose the PIC32CM2532LS60100-I/PF when you need a larger 100-pin TQFP (PF) package with up to 32 GPIO and similar security features but a smaller 256 KB Flash / 32 KB SRAM budget; both share Cortex-M23 architecture and the LS60 security tier.
What is the best drop-in replacement for PIC32CM5164LS60064-I/5LX?
The best drop-in replacement is the PIC32CM5164LS00064-I/5LX from Microchip, which shares the same 64-pin VQFN (5LX) footprint, 512 KB Flash, 64 KB SRAM, and pinout, but omits the embedded ATECC608 secure element. According to the Microchip family documentation, the LS00064 is software- and pin-compatible with the LS60064 except for security features; use it when TrustZone or hardware-rooted secure boot is not required.
Where can I download the PIC32CM5164LS60064-I/5LX datasheet PDF?
The official PIC32CM LE00/LS00/LS60 family data sheet (document 60001615E) can be downloaded directly from Microchip at https://ww1.microchip.com/downloads/en/DeviceDoc/60001615E.pdf. This PDF covers electrical characteristics, pinout, peripheral configuration, TrustZone implementation, and package drawings for every member of the family, including the PIC32CM5164LS60064-I/5LX.
Where can I find the PIC32CM5164LS60064-I/5LX pinout diagram?
The full pinout for the 64-pin VQFN (5LX) package is published in the PIC32CM LE00/LS00/LS60 family data sheet (document 60001615E), page-level pin tables, and on the Microchip product page at https://www.microchip.com/en-us/product/PIC32CM5164LS60064. Pin functions are multiplexed across SERCOM, GPIO, ADC, touch, and analog comparator blocks via the PORT and PMUX controllers.
What are the key specifications of PIC32CM5164LS60064-I/5LX that engineers should know?
Engineers evaluating the PIC32CM5164LS60064-I/5LX should focus on eight primary facts: (1) ARM Cortex-M23 core at 48 MHz, (2) 512 KB Flash plus 64 KB SRAM, (3) 2.0V to 3.63V supply, (4) -40C to +85C industrial grade, (5) 64-pin VQFN 9x9 mm package, (6) integrated ATECC608 secure element, (7) Arm TrustZone for ARMv8-M, and (8) SleepWalking low-power peripherals. Per the family data sheet 60001615E, this combination targets secure, battery-powered IoT edge nodes.

Engineering reference data for PIC32CM5164LS60064-I/5LX — comparison, design guidance, and compliance information.

Selection Guide

Choose the PIC32CM5164LS60064-I/5LX when you need a Cortex-M23 microcontroller with 512 KB Flash, 64 KB SRAM, integrated ATECC608 secure element, and TrustZone for ARMv8-M in a 64-pin VQFN (5LX) package. Pick the PIC32CM5164LS00064-I/5LX for the same footprint and memory without security features when TrustZone is not needed. Pick the PIC32CM5164LS60064T-I/5LX for tape-and-reel packaging in high-volume pick-and-place assembly. Pick the PIC32CM5164LS60064-I/5LX-PROTO for short-run prototypes. Pick the PIC32CM2532LS60100-I/PF when you need a 100-pin TQFP (PF) with the same security features but reduced 256 KB Flash / 32 KB SRAM. Pick the PIC32CM5164LS60048T-I/U5B for a smaller 48-pin VQFN design that still keeps the LS60 security tier.

Comparison with Alternatives

Parameter This Product PIC32CM5164LS00064-I/5LX PIC32CM5164LS60064T-I/5LX PIC32CM5164LS60064-I/5LX-PROTO PIC32CM2532LS60100-I/PF PIC32CM5164LS60048T-I/U5B
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Package VQFN-64 (5LX), 9x9 mm VQFN-64 (5LX), 9x9 mm - same VQFN-64 (5LX), 9x9 mm - same VQFN-64 (5LX), 9x9 mm - same TQFP-100 (PF) - different VQFN-48 (U5B) - different
Core Architecture ARM Cortex-M23 ARM Cortex-M23 ARM Cortex-M23 ARM Cortex-M23 ARM Cortex-M23 ARM Cortex-M23
Maximum CPU Frequency 48 MHz 48 MHz 48 MHz 48 MHz 48 MHz 48 MHz
Program Flash Memory 512 KB 512 KB 512 KB 512 KB 256 KB 256 KB
Operating Voltage 2.0 V to 3.63 V 1.62 V to 3.63 V 2.0 V to 3.63 V 2.0 V to 3.63 V 2.0 V to 3.63 V 2.0 V to 3.63 V
Integrated Secure Element (ATECC608) Yes No Yes Yes Yes Yes
TrustZone Support Yes No Yes Yes Yes Yes
Capacitive Touch Support Yes (water-tolerant) Yes (water-tolerant) Yes (water-tolerant) Yes (water-tolerant) Yes (water-tolerant) Yes (water-tolerant)

Key Differentiators

  • Embedded ATECC608 secure element with TrustZone for ARMv8-M (vs PIC32CM5164LS00064-I/5LX)
  • Largest Flash and SRAM in the LS60 64-pin VQFN family (vs PIC32CM5164LS60048T-I/U5B)
  • Identical silicon with relaxed cost target (vs PIC32CM5164LS60064-I/5LX-PROTO)

Design Notes

The PIC32CM5164LS60064-I/5LX operates from 2.0V to 3.63V. For battery applications, take advantage of SleepWalking peripherals: configure the ADC, I2C, or touch peripheral to monitor external events autonomously while the CPU remains in BACKUP or OFF mode. Per the PIC32CM LS60 family data sheet (60001615E), wake-up time from BACKUP is typically 1.2 ms with full SRAM retention below 1.5 uA. Always include a 1 uF decoupling capacitor on each VDD pin plus a 100 nF high-frequency bypass placed within 2 mm of the IC.

The 64-pin VQFN (5LX) package has an exposed thermal pad (EPAD) that must be soldered to a 5x5 mm copper pour on the top layer and stitched to the inner ground plane with at least eight thermal vias (0.3 mm drill, 0.5 mm pitch). According to Microchip soldering profiles for VQFN packages, follow the JEDEC J-STD-020 reflow profile with peak temperature 245C for lead-free assembly. Keep high-speed SERCOM traces length-matched within 0.5 mm and route them over an unbroken reference plane to maintain signal integrity on SPI and I2C peripherals.

For capacitive touch performance, isolate each touch sensor pad with a hatched ground pour separated by at least 0.5 mm to prevent false touches. Water-tolerant touch tuning requires careful PCB stack-up: use a 0.8 mm to 1.6 mm overlay (glass or plastic) and follow Microchip application note AN2934 for sensor layout. Route analog op-amp outputs on a separate layer with a quiet analog ground island that connects to the digital ground at a single point near the IC GND pins.

Estimated: based on a typical 48 MHz active current of about 7 mA from the family data sheet, and a typical VDD of 3.3V, a 3-volt Li coin cell (CR2032, 220 mAh) supplies roughly 11 hours of continuous active runtime. To extend lifetime, ensure firmware puts the CPU in SleepWalking or BACKUP mode whenever possible and disables unused SERCOM peripherals via the PMUX register. Avoid leaving the SWD pins floating in production: route them to a test pad or pull-up to prevent accidental reset or debug-entry glitches.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Qualified
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

RoHS compliant and lead-free per Microchip product page. I-grade (industrial) temperature range -40C to +85C; AEC-Q100 automotive qualification is NOT available on this part. For automotive applications consider PIC32CM variants explicitly labeled as automotive grade.

Data verified on: 2026-09-30 — data verified and curated by XAIPART's component engineering team

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Microchip Technology PIC32CM5164LS60064 PIC32CM5164LS00064 PIC32CM5164LS60064T PIC32CM2532LS60100 PIC32CM5164LS60048 ARM Cortex-M23 ARMv8-M TrustZone ATECC608 secure element microcontroller MCU VQFN-64 5LX package Capacitive touch mTouch SleepWalking NVIC Memory Protection Unit industrial temperature grade RoHS 12-bit ADC ECDSA
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