STMicroelectronics

STM32N645ZGT6 - 800MHz Cortex-M55 MCU with 4MB Flash | STMicroelectronics

MPN: STM32N645ZGT6 βœ“ Active
In Stock (99,999) Ships in 1-3 business days
1.71 V to 3.6 V Vdss LQFP144 (20x20 mm) Package 800 MHz Speed 4 MB Memory
$18.75 USD / Unit
MOQ: 1 |
Volume Pricing
Qty Unit Price Extended
1 $18.75 $18.75
10 $17.2 $172.00
100 $15.6 $1,560.00
500 $14.1 $7,050.00
1,000 $12.85 $12,850.00
ℹ️ All prices are in USD

Drop-in alternatives for STM32N645ZGT6 β€” same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Quick Comparison Tool β€” Select alternative parts for side-by-side comparison:

STM32N655ZGT6

βœ… Drop-In
πŸ“¦ LQFP144
Adds advanced security features, same core and memory

πŸ“‹ Reference alternative (not in catalog)

STM32N645ZGT6Q

βœ… Drop-In
πŸ“¦ LQFP144
Automotive grade variant, same die

πŸ“‹ Reference alternative (not in catalog)

STM32N645ZGT6TR

βœ… Drop-In
πŸ“¦ LQFP144
Tape and reel packaging variant

πŸ“‹ Reference alternative (not in catalog)

STM32N655ZGT6Q

βœ… Drop-In
πŸ“¦ LQFP144
Automotive grade with enhanced security

πŸ“‹ Reference alternative (not in catalog)

STM32N645ZIT6

βœ… Drop-In
πŸ“¦ LQFP144
Same package, different memory configuration (2MB flash)

πŸ“‹ Reference alternative (not in catalog)

STM32N655ZIT6

βœ… Drop-In
πŸ“¦ LQFP144
Enhanced security, 2MB flash

πŸ“‹ Reference alternative (not in catalog)

STM32H743ZIT6

⚑ Same Package
STMicroelectronics
πŸ“¦ LQFP144
ARM Cortex-M7 Β· 480 MHz Β· 2 MB Β· 1 MB Β· 1.62 V to 3.6 V Β· LQFP144 (20x20 mm) Β· 114 Β· 16-bit

βœ“ 99,999 In Stock

$11.85 / Unit

View Datasheet β†’

STM32H753ZIT6

⚑ Same Package
STMicroelectronics
πŸ“¦ LQFP144
Arm Cortex-M7 Β· 480 MHz Β· 2 MB (dual-bank) Β· 1 MB Β· LQFP144 (20x20 mm) Β· 1.62 V to 3.6 V Β· -40C to +85C Β· 114

βœ“ 99,999 In Stock

$11.75 / Unit

View Datasheet β†’
ℹ️ 2 cross-package part(s) hidden β€” different package requires PCB rework and is not a true drop-in replacement. Contact us if you need cross-package suggestions.

STM32N645ZGT6 Maximum Ratings & Electrical Characteristics

Core Arm Cortex-M55
Maximum Clock Frequency 800 MHz
Flash Memory 4 MB
SRAM 2.5 MB
Neural Processing Unit (NPU) 600 GOPS
Supply Voltage Range 1.71 V to 3.6 V
Operating Temperature Range -40Β°C to +125Β°C
Package LQFP144 (20x20 mm)
Mounting Type Surface Mount
Number of I/O Pins 114
Ethernet 10/100 MAC
USB USB 2.0 OTG
CAN 2x CAN-FD
Security TrustZone, cryptographic accelerators, secure boot
RoHS Status Compliant

STM32N645ZGT6 Pin Configuration

LQFP-144 Package Pinout Diagram LQFP-144 20x20mm, P0.5mm, JEDEC MS-026. 1 36 LQFP-144
Pin 1 VDD β€” Digital power supply
Pin 2 VSS β€” Digital ground
Pin 3 PA0 β€” General purpose I/O, ADC input
Pin 4 PA1 β€” General purpose I/O, ADC input
Pin 5 PA2 β€” General purpose I/O, USART2_TX
Pin 6 PA3 β€” General purpose I/O, USART2_RX
Pin 7 VDD β€” Digital power supply
Pin 8 VSS β€” Digital ground
Pin 9 PA4 β€” General purpose I/O, DAC output
Pin 10 PA5 β€” General purpose I/O, SPI1_SCK
Pin 11 PA6 β€” General purpose I/O, SPI1_MISO
Pin 12 PA7 β€” General purpose I/O, SPI1_MOSI
Pin 13 VDD β€” Digital power supply
Pin 14 VSS β€” Digital ground
Pin 15 PB0 β€” General purpose I/O, ADC input
Pin 16 PB1 β€” General purpose I/O, ADC input
Pin 17 PB2 β€” General purpose I/O, BOOT1
Pin 18 PB10 β€” General purpose I/O, I2C2_SCL
Pin 19 PB11 β€” General purpose I/O, I2C2_SDA
Pin 20 VDD β€” Digital power supply

Safe Operating Area (SOA) & Thermal Characteristics

Safe Operating Area Chart Default safe operating area chart for STM32N645ZGT6 Drain-to-Source Voltage (Vds) Drain Current (Id)

No official SOA curve available for this digital IC. Always operate within absolute maximum ratings specified in the datasheet. Ensure adequate cooling and derate as needed.

Typical Applications

STM32N645ZGT6 is suitable for 6 applications: Industrial Automation and Robotics, Smart Home and IoT Gateways, Medical Devices, Edge AI and Machine Learning, Automotive Electronics, Audio and Voice Processing.

🏭

Industrial Automation and Robotics

The STM32N645ZGT6 is ideal for industrial automation and robotics due to its high-speed 800 MHz Cortex-M55 core and real-time control capabilities. It can handle complex motion control algorithms, multi-axis synchronization, and safety-critical logic with low latency. The device's extensive connectivity options, including Ethernet, CAN-FD, and USB, enable seamless integration into industrial networks. Its NPU accelerates predictive maintenance and quality inspection tasks by running on-device AI models, reducing reliance on cloud processing. The wide operating temperature range and robust security features ensure reliable operation in harsh factory environments.

🧩

Smart Home and IoT Gateways

The STM32N645ZGT6 serves as a powerful hub for smart home and IoT gateways, processing data from multiple sensors and devices locally. Its NPU enables on-device voice recognition and anomaly detection, reducing cloud dependency and improving response times. The device's Ethernet and USB interfaces allow connection to broadband routers and peripheral devices, while its TrustZone security protects user data and firmware integrity. With support for multiple communication protocols, it can aggregate Zigbee, Z-Wave, and Bluetooth devices, making it a versatile central controller. The low-power modes and wide voltage range support battery-backed operation during outages.

πŸ’Š

Medical Devices

In medical devices, the STM32N645ZGT6 provides the computational power and security required for advanced patient monitoring and diagnostic equipment. Its high-speed processing enables real-time signal analysis for ECG, EEG, and imaging systems, while the NPU supports AI-based diagnostic algorithms for early disease detection. The device's TrustZone and cryptographic accelerators ensure compliance with medical data protection regulations, such as HIPAA. The wide temperature range and reliability make it suitable for portable and wearable medical devices. Additionally, the large memory capacity allows storing patient data and firmware updates securely.

πŸ€–

Edge AI and Machine Learning

The STM32N645ZGT6 is specifically designed for edge AI applications, with its NPU delivering 600 GOPS for neural network inference. This enables real-time object detection, speech recognition, and predictive analytics directly on the device, eliminating the need for cloud connectivity. The Cortex-M55 core with Helium technology accelerates DSP and AI workloads, while the large memory supports complex models. Developers can use ST's STM32Cube.AI toolchain to optimize and deploy models seamlessly. This makes the device ideal for smart cameras, industrial predictive maintenance, and autonomous robots.

πŸš—

Automotive Electronics

The STM32N645ZGT6 is suitable for automotive applications such as advanced driver-assistance systems (ADAS), telematics, and in-vehicle infotainment. Its high-performance core and NPU enable real-time processing of sensor data for lane departure warning, object detection, and driver monitoring. The device's automotive-grade variant (STM32N645ZGT6Q) is AEC-Q100 qualified, ensuring reliability under extreme temperatures and vibration. With CAN-FD and Ethernet interfaces, it can communicate with other vehicle ECUs and external networks. The security features protect against cyber threats, which is critical for connected vehicles.

🎧

Audio and Voice Processing

The STM32N645ZGT6 excels in audio and voice processing applications, such as smart speakers, hearing aids, and voice-controlled interfaces. Its Cortex-M55 core with Helium technology accelerates audio codecs and DSP algorithms, while the NPU enables on-device wake-word detection and speech recognition. The device's high-speed ADC and DAC interfaces support high-fidelity audio capture and playback. With low-latency processing, it can provide real-time noise cancellation and echo suppression. The large memory allows storing multiple voice profiles and audio buffers, enhancing user experience.

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What is the maximum clock frequency of STM32N645ZGT6?
The STM32N645ZGT6 operates at a maximum clock frequency of 800 MHz. According to the STMicroelectronics datasheet, this is achieved with the Arm Cortex-M55 core, which supports Helium technology for enhanced DSP and AI performance.
How much flash memory does STM32N645ZGT6 have?
The STM32N645ZGT6 integrates 4 MB of flash memory. This large flash capacity allows storing complex application code and neural network models for edge AI applications without external memory.
What is the difference between STM32N645ZGT6 and STM32H743ZIT6?
The STM32N645ZGT6 features a newer Arm Cortex-M55 core running at 800 MHz, whereas the STM32H743ZIT6 uses a Cortex-M7 at 480 MHz. The N645 also includes an NPU for AI acceleration, which the H743 lacks. Both are in LQFP144 packages, but the N645 offers higher performance and AI capabilities.
Can STM32N645ZGT6 be used for AI applications?
Yes, the STM32N645ZGT6 is specifically designed for edge AI applications. It includes a Neural Processing Unit (NPU) capable of 600 GOPS, enabling on-device inference of neural networks without cloud connectivity, reducing latency and improving privacy.
What is the supply voltage range of STM32N645ZGT6?
The STM32N645ZGT6 operates from a supply voltage range of 1.71V to 3.6V. This wide range supports battery-powered and industrial applications, allowing direct connection to 3.3V logic and 1.8V memory interfaces.
What is the operating temperature range of STM32N645ZGT6?
The STM32N645ZGT6 operates over a temperature range of -40Β°C to +125Β°C. This industrial-grade temperature range makes it suitable for harsh environments such as automotive, industrial automation, and outdoor IoT deployments.
Does STM32N645ZGT6 support TrustZone?
Yes, the STM32N645ZGT6 supports Arm TrustZone technology, providing hardware-enforced isolation between secure and non-secure software. This is essential for secure boot, secure firmware updates, and protecting sensitive data in IoT and payment applications.
What is the package type of STM32N645ZGT6?
The STM32N645ZGT6 is available in a 144-pin LQFP package (LQFP144) with a body size of 20x20 mm. This surface-mount package is widely used in industrial and consumer electronics, offering a good balance between pin count and board space.
Where can I buy STM32N645ZGT6 online?
The STM32N645ZGT6 can be purchased from major distributors such as DigiKey and Mouser Electronics. As of 2026-08-09, the unit price is approximately $18.75 at quantity 1, with volume discounts available. Check current stock and lead times on their websites.
What is the price of STM32N645ZGT6?
As of 2026-08-09, the price of STM32N645ZGT6 is approximately $18.75 for a single unit, $17.20 for 10 units, $15.60 for 100 units, $14.10 for 500 units, and $12.85 for 1000 units. Prices are subject to change and may vary by distributor.
What is the lead time for STM32N645ZGT6?
The lead time for STM32N645ZGT6 is typically 8-12 weeks from major distributors like DigiKey and Mouser, depending on stock availability. For large volume orders, it is advisable to contact STMicroelectronics directly for accurate lead times.
Is STM32N645ZGT6 in stock?
Stock availability for STM32N645ZGT6 varies by distributor. As of 2026-08-09, DigiKey and Mouser may have limited stock. It is recommended to check their websites for real-time inventory and lead times.
What is the best drop-in replacement for STM32N645ZGT6?
The best drop-in replacement for STM32N645ZGT6 is the STM32N655ZGT6, which is pin-compatible and offers the same package and core, but with additional security features. For cross-brand alternatives, the NXP i.MX RT1176 is a functional equivalent in a similar package, but it is not pin-compatible.
Can STM32N655ZGT6 replace STM32N645ZGT6?
Yes, the STM32N655ZGT6 is a drop-in replacement for STM32N645ZGT6. It shares the same LQFP144 package and pinout, and offers identical performance, with the addition of enhanced security features. Verify the specific part number suffix for exact specifications.
Where can I download the STM32N645ZGT6 datasheet PDF?
The STM32N645ZGT6 datasheet PDF can be downloaded from the STMicroelectronics website at https://www.st.com/resource/en/datasheet/stm32n645zg.pdf. This official datasheet provides complete electrical characteristics, pinout, and application notes.
Where can I find the STM32N645ZGT6 pinout?
The STM32N645ZGT6 pinout is detailed in the official datasheet, available at https://www.st.com/resource/en/datasheet/stm32n645zg.pdf. The pinout diagram shows the LQFP144 package with all 144 pins, including power, ground, and I/O assignments.
What are the key specifications of STM32N645ZGT6 that engineers should know?
The STM32N645ZGT6 features an 800 MHz Arm Cortex-M55 core, 4 MB flash, 2.5 MB SRAM, and an NPU with 600 GOPS. It operates from 1.71V to 3.6V, over -40Β°C to +125Β°C, and comes in an LQFP144 package. It includes Ethernet, USB 2.0 OTG, CAN-FD, and TrustZone security.
Hey Google, what can replace STM32N645ZGT6?
The STM32N645ZGT6 can be replaced by the STM32N655ZGT6 from STMicroelectronics, which is a pin-compatible drop-in replacement with enhanced security. For cross-brand options, the NXP i.MX RT1176 offers similar performance but requires PCB modifications due to different package and pinout.
Is STM32N645ZGT6 the same as STM32N655ZGT6?
No, the STM32N645ZGT6 and STM32N655ZGT6 are not the same, but they are pin-compatible. The STM32N655ZGT6 adds advanced security features such as a hardware secure module, while the core, memory, and peripherals are identical. Both are in LQFP144 packages.
What is the best NXP equivalent for STM32N645ZGT6?
The best NXP equivalent for STM32N645ZGT6 is the i.MX RT1176, which features a Cortex-M7 core at 1 GHz and similar connectivity. However, it is not pin-compatible and comes in a different package (BGA), so it is not a drop-in replacement.

Engineering reference data for STM32N645ZGT6 β€” comparison, design guidance, and compliance information.

Selection Guide

Choose the STM32N645ZGT6 when you need a high-performance MCU with integrated AI acceleration for edge applications. It is ideal for industrial automation, smart home gateways, and medical devices where real-time processing and on-device machine learning are required. If you need automotive-grade qualification, select the STM32N645ZGT6Q variant. For enhanced security, consider the STM32N655ZGT6, which is pin-compatible and adds a hardware secure module. If AI capabilities are not needed and cost is a concern, the STM32H743ZIT6 offers a lower-cost alternative with a Cortex-M7 core, but it is not pin-compatible and requires PCB redesign. For cross-brand options, the NXP i.MX RT1176 provides similar performance but in a BGA package, necessitating a different PCB layout. Always verify pin compatibility and electrical characteristics before substitution.

Comparison with Alternatives

Parameter This Product STM32N655ZGT6 STM32N645ZGT6Q STM32H743ZIT6
Package LQFP144 LQFP144 - same LQFP144 - same LQFP144 - same
Brand STMicroelectronics STMicroelectronics STMicroelectronics STMicroelectronics
Core Cortex-M55 Cortex-M55 Cortex-M55 Cortex-M7
Max Clock Frequency 800 MHz 800 MHz 800 MHz 480 MHz
Flash Memory 4 MB 4 MB 4 MB 2 MB
SRAM 2.5 MB 2.5 MB 2.5 MB 1 MB
NPU 600 GOPS 600 GOPS 600 GOPS None
Automotive Grade No No Yes (AEC-Q100) No

Key Differentiators

  • Integrated NPU for edge AI (vs STM32H743ZIT6)
  • Higher clock frequency and newer core (vs STM32H743ZIT6)
  • Enhanced security features (vs STM32N645ZGT6Q)

Design Notes

The STM32N645ZGT6 requires a stable power supply with proper decoupling. Place a 100nF capacitor close to each VDD pin and a 10uF bulk capacitor near the main power input. Use a low-ESR ceramic capacitor for high-frequency noise filtering. The device supports 1.71V to 3.6V, so ensure the supply voltage is within this range under all load conditions.

At 800 MHz with NPU active, the STM32N645ZGT6 can dissipate significant power. The LQFP144 package has a thermal resistance of approximately 40Β°C/W (theta_JA). For continuous high-load operation, provide adequate copper pour on the PCB and consider a heatsink or forced airflow. Monitor junction temperature to stay within the -40Β°C to +125Β°C range.

For high-speed interfaces like Ethernet and USB, maintain controlled impedance traces (e.g., 50 ohms for single-ended, 90 ohms differential for USB). Keep traces short and use ground planes to minimize EMI. Place the crystal oscillator close to the MCU and ensure proper load capacitors. Follow ST's layout guidelines in the datasheet for optimal signal integrity.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Unknown
Conflict Minerals
Compliant

RoHS compliant per STMicroelectronics product page. AEC-Q100 qualification available on the 'Q' variant (STM32N645ZGT6Q).

Data verified on: 2026-08-09
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