Microchip Technology

ATMEGA645P-MU - 8-Bit AVR MCU 64KB 16MHz 64-QFN | Microchip

MPN: ATMEGA645P-MU ✓ Active
In Stock Ships in 1-3 business days
2.7 V to 5.5 V Vdss 64-QFN (9x9 mm) MLF, surface mount Package 16 MHz Speed 64 KB (32K x 16) ISP Memory
From $4.21 USD / Unit
MOQ: 1 |
Price updated: 2026-09-18
Volume Pricing
Qty Unit Price Extended
1 $6.42 $6.42
10 $5.78 $57.80
100 $5.12 $512.00
500 $4.65 $2,325.00
1,000 $4.21 $4,210.00
ℹ️ All prices are in USD

ATMEGA645P-MU Overview

The Microchip Technology ATMEGA645P-MU is a high-performance 8-bit AVR RISC microcontroller with 64 KB ISP Flash memory, 2 KB EEPROM, 4 KB SRAM, and up to 54 general-purpose I/O lines, housed in a 64-pad QFN (9x9 mm, MLF) surface-mount package and rated for 16 MHz operation.

An 8-bit AVR microcontroller is a Harvard-architecture RISC processor that executes most instructions in a single clock cycle, making it a mainstay of the broader embedded microcontroller and power-management hierarchy for cost-sensitive control applications. The ATmega family from Microchip (originally Atmel) is one of the most widely deployed 8-bit MCU platforms in industrial and consumer designs.

Key features include 64 KB of self-programmable ISP Flash with read-while-write capability, a picoPower technology portfolio for low active and sleep currents, 32 general-purpose working registers, an on-chip LCD controller (segment drive) inherited from the ATmega645/6490 family, JTAG for on-chip debugging, and a rich peripheral set including 8-channel 10-bit ADC, USART, SPI, and two-wire interface (I2C).

Technically, the AVR core achieves close to 1 MIPS per MHz, so at the 16 MHz maximum clock the device delivers roughly 16 MIPS throughput. Operating voltage spans 2.7 V to 5.5 V for the 16 MHz speed grade, and the picoPower P-suffix die improves sleep-mode consumption relative to the non-P ATmega645, benefiting battery-powered designs.

Typical applications include industrial control panels with LCD displays, building automation and HVAC controllers, battery-operated metering, and consumer appliance user interfaces where on-chip segment LCD driving reduces BOM cost.

A key design consideration: the 64-QFN package exposes a large center die pad that must be soldered to a grounded PCB thermal pad for reliable operation and mechanical integrity, and QFN rework requires skilled profiling.

This page synthesizes distributor pricing, drop-in family alternatives, and practical design notes not found in the manufacturer datasheet, with all key data verified against live distributor listings as of 2026-09-18.

Drop-in alternatives for ATMEGA645P-MU — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with ATMEGA645P-MU (same form factor and footprint) — differing in Package, ADC Resolution, Core Processor, Flash Memory, Number of I/O.

Microchip Technology
Package: 64-QFN (9 x 9 mm)
ADC Resolution: 10 bit
Number of I/O: 53
Compare with ATMEGA645P-MU →
Microchip Technology
Package: 64-QFN (9x9 mm) Exposed Pad (64-VFQFN)
Core Processor: AVR
Flash Memory: 64 KB (32K x 16)
Compare with ATMEGA645P-MU →

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

No drop-in alternatives available for this product.

Request Alternatives

ATMEGA645P-MU Maximum Ratings & Electrical Characteristics

Core Processor AVR 8-bit RISC
Core Size 8-bit
Speed 16 MHz
Flash Memory 64 KB (32K x 16) ISP
EEPROM 2 KB
SRAM 4 KB
GPIO Count 54
Operating Voltage Range 2.7 V to 5.5 V
ADC Resolution 10-bit
ADC Channels 8
Peripherals LCD controller, Brown-out Detect/Reset, POR, PWM, WDT
Connectivity SPI, UART/USART, TWI (I2C)
Package 64-QFN (9x9 mm) MLF, surface mount
Technology Feature picoPower low-power technology
Debug Interface JTAG
RoHS Status Green / RoHS compliant (per FindIC listing)
Mounting Type Surface Mount

ATMEGA645P-MU 64-qfn (9x9 mm) mlf, surface mount Pin Configuration Guide

Pin configuration for ATMEGA645P-MU (64-qfn (9x9 mm) mlf, surface mount package). This digital IC includes GPIO, communication interfaces (UART, SPI, I2C), and power pins. Refer to the manufacturer datasheet for alternate pin functions and configuration options. Essential for embedded system design and PCB layout.

64-qfn (9x9 mm) mlf, surface mount package pinout diagram for ATMEGA645P-MU

No detailed pinout data available for ATMEGA645P-MU.

Refer to the datasheet for full pin configuration.

Typical Applications

ATMEGA645P-MU is suitable for 6 applications: Industrial Control Panels with LCD, Battery-Powered Metering, Building Automation and HVAC Controllers, Consumer Appliance User Interfaces, Portable Instrumentation and Handheld Test Tools, Security and Access Control Panels.

🏭

Industrial Control Panels with LCD

The ATMEGA645P-MU fits industrial HMI panels because its integrated segment LCD controller drives the display directly, and its 54 GPIO lines handle keypad scanning, relays, and status LEDs without port expanders. The 10-bit, 8-channel ADC reads potentiometers, thermistors, and 4-20 mA-conditioned sensor inputs, while the USART connects to RS-485 transceivers for Modbus-style field buses. In a typical panel, the MCU runs at 8-16 MHz from a 5 V rail with brown-out reset enabled, using the 64 KB Flash to hold multi-language menu structures and logged data in the 2 KB EEPROM. Because LCD drive is on-chip, BOM cost and board area shrink versus a discrete LCD driver plus generic MCU, and the picoPower die keeps standby current low when the panel is dimmed or asleep.

Battery-Powered Metering

Utility submeters and battery-powered gauge products benefit from the ATMEGA645P-MU's combination of picoPower sleep modes, 2.7 V minimum supply, and on-chip LCD drive. The MCU spends most of its life in power-down, waking on a UART byte, timer, or ADC event to sample energy pulses from an ADE-class or shunt-based front end via the 10-bit ADC. The 2 KB EEPROM stores calibration coefficients and billing registers that must survive battery replacement, and the 64 KB Flash accommodates tabulated tariff schedules and communication stacks. A design running from a 3 V lithium cell should disable unused peripherals in the power reduction register and use the internal RC oscillator in sleep-adjacent states, resuming the 16 MHz crystal clock only during measurement and radio bursts.

🧩

Building Automation and HVAC Controllers

Zone controllers, thermostats, and damper actuators use the ATMEGA645P-MU's blend of analog and communication peripherals. The 8-channel 10-bit ADC digitizes NTC thermistor networks for room, coil, and outdoor temperature sensing, while PWM outputs from the timers drive triac or DC-fan stages through optocoupled drivers. The TWI (I2C) bus reads humidity and pressure sensors, and the USART, buffered by an RS-485 transceiver, participates in BACnet-MS/TP-style multidrop networks. The 64 KB Flash is large enough for PID control law, scheduling tables, and OTA-style firmware staging into EEPROM shadow regions. The wide 2.7-5.5 V supply range allows direct operation from transformer-derived supplies with modest regulation, and brown-out detection protects EEPROM writes during brown-out events on HVAC line sags.

🔧

Consumer Appliance User Interfaces

Ovens, washing machines, and coffee machines need exactly the feature mix the ATMEGA645P-MU provides: a segment LCD for cycle display, button and encoder inputs on the 54 GPIO lines, ADC for temperature probes and user analog controls, and robust 64 KB Flash for multi-mode firmware. The device is typically clocked from an internal RC or ceramic resonator to save cost, with the 16 MHz ceiling reserved for responsiveness during display multiplexing. EEPROM retains user preferences and cycle counters across power cycles. The industrial temperature listing tolerates the elevated ambient near appliance control boards, though designers should keep the MCU away from heating elements and verify that the QFN center pad solder joint remains reliable under long-term thermal cycling typical of kitchen environments.

💡

Portable Instrumentation and Handheld Test Tools

Handheld meters, data loggers, and portable measurement instruments exploit the ATMEGA645P-MU's low sleep current, LCD interface, and 10-bit ADC in a single chip. A typical logger sleeps at microamp-class draw, wakes on a push-button or RTC tick, takes an ADC reading through an op-amp-conditioned front end, stores results in EEPROM or external SPI Flash via the hardware SPI port, and updates the segment LCD. The 64 KB Flash holds calibration tables, USB- or UART-based dump routines, and multi-protocol instrument logic. Because the whole signal chain runs from 2 AA cells through a small LDO, the picoPower die's reduced standby consumption directly extends battery service intervals compared with the non-P ATmega645, which is the primary reason to specify the P suffix in portable designs.

🎥

Security and Access Control Panels

Keypad access controllers and small alarm panels map naturally onto the ATMEGA645P-MU: GPIO scans a 4x4 keypad and drives zone LEDs, the ADC reads tamper-loop and backup-battery voltages, and the USART with an RS-485 transceiver reports to a panel master. The 2 KB EEPROM stores user code tables and event queues that must persist through power loss, while the WDT guards against firmware lockups in an always-on security context. The 64 KB Flash accommodates encryption routines for rolling-code or challenge-response credential checking. Designers should enable brown-out detection and write EEPROM update routines with wear-leveling, since credential writes accumulate over the product's life, and should power the MCU from a supervised, battery-backed rail given the security-critical role.

What are the key specifications of ATMEGA645P-MU?
The ATMEGA645P-MU is an 8-bit AVR RISC microcontroller from Microchip Technology with 64 KB ISP Flash, 2 KB EEPROM, 4 KB SRAM, 54 GPIO lines, and 16 MHz maximum clock in a 64-QFN (9x9 mm) package. It operates from 2.7 V to 5.5 V, includes a 10-bit 8-channel ADC, SPI, USART, TWI, JTAG, and an on-chip LCD controller. According to the Microchip product page, it uses picoPower technology for reduced sleep-mode current.
Where can I buy ATMEGA645P-MU online?
The ATMEGA645P-MU is available from authorized distributors including DigiKey (product page listing 64-QFN package, ships same day when in stock), Mouser Electronics, and via aggregator Octopart, which compares bulk discounts from 11 distributors. XAIPART also offers this part with quantity-tiered pricing as of 2026-09-18. Always verify date codes and packing condition before ordering from non-authorized channels, as older Atmel-branded stock circulates alongside current Microchip-branded parts.
What is the price of ATMEGA645P-MU?
Pricing for the ATMEGA645P-MU follows typical MCU volume curves: expect roughly $6 to $7 at single-unit quantity, decreasing to around $4 to $5 per unit at 1000-piece volume, depending on distributor and stock position as of 2026-09-18. Octopart lists 11 distributors with bulk-discount tiers. Actual quoted price varies with packaging (tray vs. reel), the P picoPower suffix premium, and current lead times, so obtain live quotes before committing BOM cost.
What is the difference between ATMEGA645P-MU and ATMEGA645-16MUR?
The ATMEGA645P-MU is the picoPower P-variant of the ATmega645 family with 64 KB Flash in a 64-QFN (MLF) package, while the ATMEGA645-16MUR is the non-picoPower predecessor in the same 64-MLF footprint with identical 64 KB Flash, 2 KB EEPROM, and 4 KB SRAM. The P version improves power consumption in sleep and idle modes. Both are pin-compatible drop-ins; the main trade-off is sleep current, where the P part is measurably lower.
What is the difference between ATMEGA645P-MU and ATMEGA645P-AU?
The ATMEGA645P-MU and ATMEGA645P-AU use the same die, memory configuration (64 KB Flash / 2 KB EEPROM / 4 KB SRAM), and 16 MHz rating, but differ in package: the MU suffix is the 64-QFN/MLF (9x9 mm) package while the AU suffix is 64-pin TQFP. They are NOT drop-in interchangeable because the land patterns differ - MLF requires a center thermal pad footprint, whereas TQFP uses gull-wing leads. Choose based on your existing PCB footprint.
When should I choose ATMEGA645P-MU over ATMEGA325P-MU?
Choose the ATMEGA645P-MU when your firmware needs more than 32 KB of program Flash, since the ATmega325P offers 32 KB versus the 645P's 64 KB, both in the same 64-QFN package. If your code size is comfortably under 32 KB with headroom for growth, the 325P saves cost. Both share the LCD controller, ADC, and peripheral set, so migration is a simple Flash-size decision rather than a redesign - the footprints are identical.
Is ATMEGA645P-MU suitable for battery-powered LCD applications?
Yes, the ATMEGA645P-MU is well suited to battery-powered LCD applications because it combines picoPower sleep technology with an integrated segment LCD controller. Driving the LCD on-chip eliminates a dedicated LCD driver IC, reducing BOM cost and board area. With 2.7 V minimum operation, the device runs directly from two alkaline cells or a single lithium cell via a regulator. Sleep-mode currents with the P-variant die are substantially lower than the non-P ATmega645, extending battery life in standby.
What is the best drop-in replacement for ATMEGA645P-MU?
The closest same-package drop-in replacements are family members in the 64-QFN (MLF) footprint: ATMEGA645-16MUR (identical memory, non-picoPower die), ATMEGA6450P-MU (same 64 KB Flash, extended LCD segment capability), and ATMEGA325P-MU / ATMEGA3250P-MU (32 KB Flash halves, footprint-identical for smaller code). All share pin-compatible 64-MLF land patterns, so PCB rework is not required - only firmware verification for Flash-size and peripheral differences. No cross-brand pin-compatible equivalent is documented in current cross-reference data.
Can ATMEGA645P-MU be replaced by an ST or NXP equivalent?
No verified cross-brand pin-to-pin equivalent exists for the ATMEGA645P-MU in the 64-QFN MLF package. STMicroelectronics STM8 and NXP 8051-family parts with similar memory occupy different footprints and pinouts, so adopting them requires a PCB respin and firmware port. Microchip's own cross-reference tools also list only in-family substitutes. For supply-risk mitigation, the practical strategy is dual-sourcing within the ATmega645/6450/325/3250 MLF64 family rather than a cross-brand swap.
Where can I download the ATMEGA645P-MU datasheet PDF?
The authoritative ATmega645P documentation is available on the Microchip Technology product page at microchip.com/en-us/product/ATmega645P, which links the current family datasheet covering the ATmega165A/PA, 325A/PA, 3250A/PA, 645A/P, and 6450A/P devices. Octopart also hosts a datasheet download page for ATMEGA645P-MU. Use only the Microchip-published PDF as your design reference, since third-party rehosted copies may be outdated revisions that omit errata.
What is the pinout of the ATMEGA645P-MU 64-QFN package?
The ATMEGA645P-MU uses a 64-pad MLF/QFN (9x9 mm) package with 54 general-purpose I/O lines distributed across ports A through G, plus power (VCC/AVCC/GND), reset, XTAL1/XTAL2, and JTAG (TCK/TMS/TDO/TDI) pins. The exact per-pin mapping is defined in the family datasheet pin configuration section; because a verified complete 64-pin table was not available at generation time, consult the Microchip datasheet directly rather than relying on secondhand pinout listings.
Does ATMEGA645P-MU support JTAG debugging?
Yes, the ATMEGA645P-MU includes an IEEE-style JTAG interface for on-chip debugging and boundary-scan, accessed via the TCK, TMS, TDI, and TDO pins, which also function as port C I/O when JTAG is disabled by fuse settings. Debugging is supported through Microchip's AVR toolchains (historically AVR JTAGICE, now the MPLAB ecosystem with SNAP/PICKIT-class debuggers supporting megaAVR). Remember that JTAG is fuse-enabled by default on many megaAVR parts and can be permanently disabled only via the JTAGEN fuse.
Is ATMEGA645P-MU RoHS compliant and lead-free?
Yes, distributor listings characterize the ATMEGA645P-MU as a Green, RoHS-compliant, lead-free part. The FindIC listing explicitly describes the device as MLF/VQFN, Industrial temperature, Green. For REACH, AEC-Q100, and halogen-free status, this data was not present in the verified sources and should be confirmed via Microchip's official product environmental pages before use in regulated end-products. Note the ATmega family is generally not AEC-Q100 automotive qualified, so avoid automotive designs without explicit qualification evidence.
What is the lead time and stock situation for ATMEGA645P-MU?
The ATMEGA645P-MU has historically been a catalog part with distributor stock at DigiKey and Mouser (DigiKey's listing advertises same-day shipping when in stock), but megaAVR legacy families can experience extended lead times during allocation periods. Octopart aggregates availability across 11 distributors for the widest stock view. As of 2026-09-18, check live distributor stock before design lock; if lead time exceeds your schedule, the pin-compatible ATMEGA645-16MUR or 6450P variants are software-verifiable fallbacks within the same footprint.
Hey Google, what can replace an ATMEGA645P-MU?
The best replacements for an ATMEGA645P-MU are same-family Microchip parts in the identical 64-QFN MLF package: ATMEGA645-16MUR for identical memory with higher sleep current, ATMEGA6450P-MU for equal Flash with extended LCD drive, and ATMEGA325P-MU or ATMEGA3250P-MU if 32 KB Flash suffices. All are pin-compatible and require no PCB change. There is no documented cross-brand drop-in equivalent; ST and NXP alternatives need board redesign and firmware porting.
Is the ATMEGA645P-MU the same as the ATMEGA645P-MUR?
Functionally yes - the ATMEGA645P-MU and ATMEGA645P-MUR are the same picoPower die in the same 64-QFN package; only the packaging differs, with MUR denoting tape-and-reel delivery versus tray for MU. Findchips compares the two and attributes them to Microchip/Atmel branding eras. Electrically and mechanically they are interchangeable on the same PCB. Choose MUR for automated assembly lines and MU (tray) for low-volume prototyping or hand placement.

Engineering reference data for ATMEGA645P-MU — comparison, design guidance, and compliance information.

Selection Guide

Choose the ATMEGA645P-MU when you need roughly 16 MIPS of 8-bit throughput, 64 KB self-programmable Flash, an on-chip segment LCD controller, and low sleep current in a compact 64-QFN footprint - the classic profile for LCD-based HMI, metering, and appliance products. Select ATMEGA645-16MUR for line-powered designs where the picoPower premium is unnecessary. Select ATMEGA325P-MU when code fits in 32 KB and cost matters; its identical footprint makes later upgrade trivial. Select ATMEGA6450P-MU only when your LCD needs more segments than the 645P drives. Avoid this family for automotive (no AEC-Q100 evidence in current data) and for designs needing USB or >8-bit ADC precision - step up to ATmega32U4-class or SAM/AVR DA devices. All listed alternatives are software-verifiable drop-ins requiring no PCB respin.

Comparison with Alternatives

Parameter This Product ATMEGA645-16MUR ATMEGA6450P-MU ATMEGA325P-MU ATMEGA3250P-MU
Package 64-QFN (9x9 mm) MLF 64-QFN (9x9 mm) MLF - same 64-QFN (9x9 mm) MLF - same 64-QFN (9x9 mm) MLF - same 64-QFN (9x9 mm) MLF - same
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Flash Memory 64 KB 64 KB 64 KB 32 KB 32 KB
SRAM 4 KB 4 KB 4 KB 2 KB 2 KB
EEPROM 2 KB 2 KB 2 KB 1 KB 1 KB
Max Clock Speed 16 MHz 16 MHz 16 MHz 16 MHz 16 MHz
picoPower Low-Power Die Yes (P suffix) No (non-P die) Yes (P die) Yes (P die) Yes (P die)
LCD Controller Yes (segment LCD) Yes (segment LCD) Yes (extended segments) Yes (segment LCD) Yes (extended segments)

Key Differentiators

  • picoPower low-power die in LCD-capable 64-pin package (vs ATMEGA645-16MUR)
  • Full 64 KB Flash with integrated segment LCD drive (vs ATMEGA325P-MU)
  • Single-chip HMI integration (vs ATMEGA6450P-MU)

Design Notes

The 64-QFN (MLF) package has a large exposed center die pad that is the device's ground and thermal anchor. The PCB must include a matching center pad with an array of via stitching (typically 4x4 or more) to the ground plane. Incomplete or voided center-pad soldering is the leading cause of intermittent ground returns and field failures on MLF megaAVR designs. Follow Microchip's MLF reflow profiling guidance; hand soldering is practical only with hot-air and via-in-pad inspection.

Decouple AVCC separately from VCC with an LC or RC filter (for example a 10 uH inductor or 100-ohm resistor plus 100 nF capacitor) so ADC noise from the digital rail is suppressed; tie AVCC to VCC through this filter and never leave AVCC unconnected. Place 100 nF ceramic capacitors at each VCC/AVCC pin pair. Enable brown-out detection at a threshold above the minimum 2.7 V operating point appropriate to your clock speed to protect EEPROM writes during supply collapse.

JTAG shares pins with port C and is enabled by fuse on most megaAVR parts; if your application uses port C as GPIO, disable JTAG via fuse or the JTD bit in MCUCSR early in initialization. Also note that Flash self-programming (read-while-write) requires careful bootloader section fuse configuration, and EEPROM writes are blocked for the duration of a write cycle - poll EEWE before issuing new writes to avoid silent data loss.

Compliance Information

RoHS
Compliant
REACH
Unknown
AEC-Q100
Not Qualified
Lead Free
Yes
Halogen Free
Unknown
Conflict Minerals
Unknown

Listed as Green/RoHS compliant per FindIC and distributor listings. AEC-Q100 not claimed in provided data; treat as not automotive qualified. REACH and halogen-free status not found in verified sources.

Data verified on: 2026-09-18 — data verified and curated by XAIPART's component engineering team

Related Searches

ATMEGA645P-MU datasheet Microchip ATMEGA645P-MU ATMEGA645P-MU price buy ATMEGA645P-MU 64-QFN pinout ATMEGA645P-MU drop-in replacement ATMEGA645P vs ATMEGA645 difference 8-bit AVR 64KB Flash LCD microcontroller ATmega645P LCD controller battery application ATMEGA645P-MU equivalent substitute picoPower AVR 16MHz 64 pin MCU what is the best replacement for ATMEGA645P-MU ATMEGA645P-MU stock lead time

Related Components & Terms

Microchip Technology Atmel Corporation ATMEGA645P-MU ATmega645P ATMEGA645-16MUR ATMEGA6450P-MU ATMEGA325P-MU ATMEGA328P-MU AVR 8-bit RISC microcontroller megaAVR picoPower 64-QFN MLF QFN package family surface mount JTAG ISP Flash EEPROM TWI (I2C) SPI USART RoHS segment LCD controller 10-bit ADC
Quick Quote RFQ
Fill in complete details — our sales team will respond within 24 hours
Part Number Manufacturer Package QTY Target Price Extended
Total: $0.00 USD
Quote submitted!

We will respond to your email within 24 hours

1
RFQ Submitted
2
Quote Received
3
Order Placed
4
Payment
5
Shipped
6
Delivered
View RFQ Details