Microchip Technology

ATSAMC21G16A-AUT - 48MHz Cortex-M0+ MCU, 64KB Flash, 48-TQFP | Microchip

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2.7 V to 5.5 V Vdss 48-TQFP (7x7 mm, 0.5 mm pitch) Package 48 MHz Speed 64 KB (64K x 8) Memory
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Price updated: 2026-09-20
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2,500 $2.35 $5,875.00
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ATSAMC21G16A-AUT Overview

The Microchip Technology ATSAMC21G16A-AUT is a 32-bit ARM Cortex-M0+ microcontroller from the SAM C21 family, featuring 64KB of Flash memory and operating at up to 48MHz, housed in a 48-pin TQFP (7x7 mm) package. Designed for Functional Safety (FuSa) capable applications, this AEC-Q100 Grade 1 qualified device operates across an extended temperature range of -40C to +85C and supports a wide supply voltage range of 2.7V to 5.5V.

A microcontroller (MCU) is a single-chip computer that integrates a CPU core, program and data memory, and a rich set of programmable peripherals. The ARM Cortex-M0+ is the smallest and most energy-efficient core in the Cortex-M family, optimized for cost-sensitive embedded applications that still require deterministic real-time response. Microcontrollers form a hierarchy that includes microcontrollers -> embedded processors -> semiconductors, with the SAM C21 specifically targeting industrial and commercial systems exposed to electrically noisy environments through its 5V-tolerant I/O and integrated CAN-FD support.

Key features include 64KB of embedded Flash for program storage and 8KB of SRAM for data, six SERCOM (Serial Communication Interface) modules configurable as USART, I2C, or SPI, a full-speed USB 2.0 interface, a CAN-FD controller, up to six timer/counter channels, a 12-bit ADC with up to 16 channels, and a 10-bit DAC. Functional Safety features include a dedicated Cortex-M0+ lockstep core, windowed watchdog timer, ECC on memory, brown-out detect, and a fail-safe clock monitor.

The ATSAMC21G16A-AUT uses Microchip's proprietary low-power process technology and supports Sleep, Standby, and Backup sleep modes to meet stringent power budgets in always-on industrial sensor nodes. The Cortex-M0+ core delivers 0.93 DMIPS/MHz and is fully binary-compatible with the larger Cortex-M3/M4 families, allowing easy code portability.

Typical applications include industrial CAN-FD node controllers, automotive body and HVAC modules, USB-CDC bridge devices, sensor hubs with analog front-ends, and appliance motor control. The wide 5V tolerance lets the device interface directly with industrial 24V-sourced signals through external resistor dividers without level translators, simplifying board design.

When designing with this MCU, allocate sufficient bypass capacitance (100nF X7R plus 4.7uF bulk) adjacent to each supply pin to meet the manufacturer's noise-immunity targets. Plan pin-out sharing between SERCOM, ADC, and DAC carefully; the datasheet pin-multiplexing table should be cross-checked with your schematic capture before layout commitment. Flash is rated to 10k write/erase cycles minimum per the SAM C21 datasheet.

Drop-in alternatives for ATSAMC21G16A-AUT — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with ATSAMC21G16A-AUT (same form factor and footprint) — differing in ADC, Operating Temperature, Package, DAC, SERCOM Modules.

Microchip Technology
ADC: 12-bit, up to 1 MSPS, up to 12 channels
Operating Temperature: -40 C to +85 C (automotive grade)
Package: 48-TQFP (7x7 mm)
Compare with ATSAMC21G16A-AUT →
Microchip Technology
ADC: 12-bit, up to 10 channels
Operating Temperature: -40 C to +85 C (industrial)
Package: 32-pin TQFP (7x7 mm)
Compare with ATSAMC21G16A-AUT →
Microchip Technology
ADC: 12-bit, up to 20 channels, 1 Msps
Package: 48-TQFP (7x7 mm)
DAC: 10-bit, 350 ksps
Compare with ATSAMC21G16A-AUT →
Microchip Technology
ADC: 12-bit, up to 16 channels
Operating Temperature: -40 C to +85 C
Package: 48-pin TQFP (7x7 mm)
Compare with ATSAMC21G16A-AUT →
Microchip Technology
Operating Temperature: -40C to +85C (MUT grade)
Package: 48-pin QFN (7x7 mm)
DAC: 10-bit, 350 ksps, 1 channel
Compare with ATSAMC21G16A-AUT →
Microchip Technology
ADC: 12-bit, up to 1 Msps
Operating Temperature: -40C to +105C
Package: 48-TQFP (7x7 mm)
Compare with ATSAMC21G16A-AUT →
Microchip Technology
ADC: 12-bit, up to 350 ksps
Operating Temperature: -40 C to +105 C
Package: 48-pin TQFP (7x7 mm)
Compare with ATSAMC21G16A-AUT →

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

ATSAMC21G17A-AUT

✅ Drop-In
Microchip Technology
📦 48-TQFP (7x7 mm)
ARM Cortex-M0+ · 32-bit · 48 MHz · 128 KB (128K x 8) · 16 KB · 4 KB (independent self-programmable) · 2.7 V to 5.5 V · -40 C to +85 C

✓ In Stock

$2.78 / Unit

View Datasheet →

ATSAMC21G15A-AUT

✅ Drop-In
Microchip Technology
📦 48-TQFP (7x7 mm)
Microchip Technology · SAM C21 · ARM Cortex-M0+ · 32-Bit · 48 MHz · 32 KB (32K x 8) · 4 KB · 1.62 V to 5.5 V (5V tolerant I/O)

✓ In Stock

$2.15 / Unit

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ATSAMC21G17A-AUT

✅ Drop-In ⚠️ 参数待验证
Microchip Technology
📦 48-TQFP (7x7 mm)
ARM Cortex-M0+ · 32-bit · 48 MHz · 128 KB (128K x 8) · 16 KB · 4 KB (independent self-programmable) · 2.7 V to 5.5 V · -40 C to +85 C

✓ In Stock

$2.78 / Unit

View Datasheet →

ATSAMC20G16A-AUT

✅ Drop-In
Microchip Technology
📦 48-TQFP (7x7 mm)
ARM Cortex-M0+ (32-bit) · 48 MHz · 64 KB · 8 KB · 48-TQFP (7x7 mm) · 2.7 V to 5.5 V · -40 C to +85 C (automotive grade) · 6 (configurable UART/SPI/I2C)

✓ In Stock

$2.65 / Unit

View Datasheet →

ATSAMC21E16A-AUT

✅ Drop-In
Microchip Technology
📦 32-QFN
ARM Cortex-M0+ (32-bit) · 48 MHz · 64 KB · 8 KB · 2 KB · 2.7 V to 5.5 V · 5 V tolerant · 26

✓ In Stock

$2.78 / Unit

View Datasheet →

ATSAMC21G16A-AUT Maximum Ratings & Electrical Characteristics

Core Architecture ARM Cortex-M0+ (32-bit, single-core with optional lockstep for FuSa)
Family SAM C21 Functional Safety (FuSa)
Maximum CPU Frequency 48 MHz
Program Flash Memory 64 KB (64K x 8)
SRAM 8 KB
Supply Voltage (VDD) 2.7 V to 5.5 V
Supply Voltage (VDDIO) 1.62 V to 5.5 V
Operating Temperature Grade -40C to +85C (Grade 1)
Package 48-TQFP (7x7 mm, 0.5 mm pitch)
Mounting Type Surface Mount, Tape & Reel (-AUT suffix)
SERCOM Modules 6 (configurable as USART/I2C/SPI)
CAN-FD Controller 1 (ISO 11898-1:2015 compliant)
USB Interface USB 2.0 Full-Speed Device/Host
ADC Resolution 12-bit, up to 16 channels
DAC Resolution 10-bit, 1 channel
Timer/Counters TC x6, TCC x3 (16-bit PWM)
Operating Temperature Range -40C to +125C (extended industrial)
AEC-Q100 Qualification Yes (Automotive Grade 1)
RoHS Status Compliant

ATSAMC21G16A-AUT Pin Configuration

TQFP-48 Package Pinout Diagram TQFP-48 7x7mm, P0.5mm, JEDEC MS-026. 1 12 TQFP-48
Pin 1 PA03 — GPIO/SERCOM3 PAD0/ADC AIN1
Pin 2 PA04 — GPIO/SERCOM0 PAD0/ADC AIN2
Pin 3 PA05 — GPIO/SERCOM0 PAD1/ADC AIN3
Pin 4 PA06 — GPIO/SERCOM0 PAD2/ADC AIN4
Pin 5 PA07 — GPIO/SERCOM0 PAD3/ADC AIN5
Pin 6 VDDIO — Digital I/O supply voltage
Pin 7 VDD — Core supply voltage (2.7V-5.5V)
Pin 8 GND — Common ground return
Pin 9 PA08 — GPIO/SERCOM2 PAD0/PTC XY0
Pin 10 PA09 — GPIO/SERCOM2 PAD1/PTC XY1
Pin 11 PA10 — GPIO/SERCOM2 PAD2/PTC XY2
Pin 12 PA11 — GPIO/SERCOM2 PAD3/PTC XY3
Pin 13 PA12 — GPIO/SERCOM4 PAD0/CAN RX
Pin 14 PA13 — GPIO/SERCOM4 PAD1/CAN TX
Pin 15 PA14 — GPIO/SERCOM4 PAD2/XIN32
Pin 16 PA15 — GPIO/SERCOM4 PAD3/XOUT32
Pin 17 PA16 — GPIO/SERCOM1 PAD0/PTC XY4
Pin 18 PA17 — GPIO/SERCOM1 PAD1/PTC XY5
Pin 19 PA18 — GPIO/SERCOM1 PAD2/PTC XY6
Pin 20 PA19 — GPIO/SERCOM1 PAD3/PTC XY7
Pin 21 PA20 — GPIO/SERCOM5 PAD2/TC4
Pin 22 PA21 — GPIO/SERCOM5 PAD3/TC5
Pin 23 PA22 — GPIO/SERCOM3 PAD0/TC6
Pin 24 PA23 — GPIO/SERCOM3 PAD1/TC7
Pin 25 PA24 — GPIO/SERCOM5 PAD0/USB D-
Pin 26 PA25 — GPIO/SERCOM5 PAD1/USB D+
Pin 27 PA26 — GPIO/ADC AIN8/DAC VOUT
Pin 28 PA27 — GPIO/ADC AIN9
Pin 29 PA28 — GPIO/ADC AIN10
Pin 30 PA29 — GPIO/ADC AIN11
Pin 31 PA30 — GPIO/SERCOM0 PAD2/TC1
Pin 32 PA31 — GPIO/SERCOM0 PAD3/TC2
Pin 33 PB00 — GPIO/SERCOM5 PAD2/PTC XY8
Pin 34 PB01 — GPIO/SERCOM5 PAD3/PTC XY9
Pin 35 PB02 — GPIO/SERCOM5 PAD0/PTC XY10
Pin 36 PB03 — GPIO/SERCOM5 PAD1/PTC XY11
Pin 37 PB04 — GPIO/SERCOM4 PAD0/PTC XY12
Pin 38 PB05 — GPIO/SERCOM4 PAD1/PTC XY13
Pin 39 PB06 — GPIO/SERCOM4 PAD2/ADC AIN12
Pin 40 PB07 — GPIO/SERCOM4 PAD3/ADC AIN13
Pin 41 PB08 — GPIO/SERCOM4 PAD0/TC0/USB_SOF
Pin 42 PB09 — GPIO/SERCOM4 PAD1/TC1
Pin 43 PB10 — GPIO/SERCOM4 PAD2/TC2/USB_TRACEDATA0
Pin 44 PB11 — GPIO/SERCOM4 PAD3/TC3/USB_TRACEDATA1
Pin 45 PB12 — GPIO/SERCOM4 PAD0/TC4/USB_TRACEDATA2
Pin 46 PB13 — GPIO/SERCOM4 PAD1/TC5/USB_TRACEDATA3
Pin 47 PB14 — GPIO/SERCOM4 PAD2/TC6/USB_TRACECLK
Pin 48 PB15 — GPIO/SERCOM4 PAD3/TC7/USB_TRACEDATA0

Typical Applications

ATSAMC21G16A-AUT is suitable for 7 applications: Industrial CAN-FD Node Controller, Automotive Body Control Module, USB CDC Bridge Device, Smart Sensor Hub with Analog Front-End, Appliance Motor Control (BLDC, PMSM), IoT Edge Gateway with 5V Tolerance, Appliance User Interface Board.

🏭

Industrial CAN-FD Node Controller

Industrial CAN-FD fieldbus nodes depend on deterministic real-time response and electromagnetic immunity. The ATSAMC21G16A-AUT's integrated CAN-FD controller compliant with ISO 11898-1:2015 supports 1 Mbit/s bit rates and 64-byte payloads, enabling fast cyclic data exchange between PLCs, motor drives, and remote I/O modules. The 5V-tolerant I/O banks interface directly with industrial 24V sensor signals through external resistor dividers, eliminating the cost and bulk of level shifters. Functional-safety peripherals (windowed watchdog, fail-safe clock monitor, memory ECC) qualify the device for SIL-2 capable process control designs per IEC 61508. At 48MHz, the Cortex-M0+ executes control loops with sub-microsecond latency, while AEC-Q100 Grade 1 qualification allows deployment on the factory floor within environments from -40C to +85C without derating.

🚗

Automotive Body Control Module

Body control modules in automotive gateways, lighting controllers, and HVAC actuators typically demand AEC-Q100 Grade 1 qualification, CAN-FD connectivity, and functional safety primitives. The ATSAMC21G16A-AUT delivers all three: ARM Cortex-M0+ core with optional lockstep, integrated CAN-FD with hardware-based acceptance filtering, and built-in windowed watchdog timer. The 48-TQFP package with exposed thermal pad operates reliably across -40C to +125C junction temperature, well within automotive under-hood margins. The 64KB Flash comfortably holds LIN/CAN transport layers and OBD-II diagnostic handlers, while 8KB SRAM supports multiple CAN-FD mailboxes simultaneously. Compared to legacy 16-bit automotive MCUs, the Cortex-M0+ offers 2x DMIPS per MHz and modern low-power Sleep modes for ECO standby in parked vehicles.

🧩

USB CDC Bridge Device

USB-to-UART/USB-to-SPI bridges are a standard use case for embedded development tools and industrial diagnostic dongles. The ATSAMC21G16A-AUT includes a built-in USB 2.0 Full-Speed device controller with on-chip transceivers, eliminating external PHY chips and reducing BOM to just a few passive components. The six SERCOM peripherals can be configured as USART, I2C, or SPI simultaneously, giving the CDC bridge access to multiple peripheral targets. At 48MHz the Cortex-M0+ core sustains 12 Mbit/s USB throughput with negligible buffering, while 64KB Flash holds USB descriptors, CDC class drivers, and command interpreters. The wide 5V tolerance allows direct bus-powered operation from USB VBUS, simplifying hardware design.

🧩

Smart Sensor Hub with Analog Front-End

Multi-sensor data acquisition nodes that combine analog sensors, digital I2C/SPI devices, and local processing benefit from the ATSAMC21G16A-AUT's mixed-signal peripherals. The 12-bit ADC with 16 channels handles simultaneous sampling from thermistors, pressure transducers, and strain gauges, while the 10-bit DAC supports excitation or actuator bias. Six SERCOM blocks let the MCU communicate with downstream I2C sensors, SPI ADCs, and UART modules concurrently. The AES hardware accelerator secures over-the-air data, while 8KB SRAM accommodates ring buffers for periodic sampling. Functional-safety peripherals (windowed WDT, ECC) suit medical-grade sensor hubs requiring IEC 62304 compliance.

🏭

Appliance Motor Control (BLDC, PMSM)

Variable-frequency motor drives in washing machines, refrigerator compressors, and HVAC blowers require precise PWM generation with deterministic interrupt response. The ATSAMC21G16A-AUT's three TCC (Timer/Counter for Control) modules deliver 16-bit complementary PWM with dead-band insertion and fault inputs, capable of driving half-bridge drivers for 3-phase BLDC and PMSM motors at switching frequencies up to 100kHz. The Cortex-M0+ core runs FOC (field-oriented control) algorithms within sub-10 microsecond periods at 48MHz. CAN-FD links the controller to the master appliance bus, while 5V tolerance interfaces legacy Hall-effect and back-EMF sense signals directly. AEC-Q100 Grade 1 and -40C to +85C operation suit laundry and kitchen equipment.

🌐

IoT Edge Gateway with 5V Tolerance

Edge gateways for industrial IoT aggregate sensor data via serial protocols and forward it to cloud services. The ATSAMC21G16A-AUT's 5V-tolerant I/O lets the device wire directly to industrial 24V sensors through resistor dividers, while six SERCOM blocks map to RS-485, RS-232, CAN, I2C, and SPI fieldbusses simultaneously. With 64KB Flash holding TLS 1.3 stacks, MQTT-SN clients, and edge analytics, the device runs secure field protocol translation without an external network processor. The 48-TQFP package with 0.5mm pitch supports hand-repairable prototyping and production volumes, while AEC-Q100 Grade 1 qualification and functional-safety peripherals allow deployment in mission-critical industrial environments.

🏭

Appliance User Interface Board

User interface boards in microwaves, ovens, and coffee machines combine touch sensing, LED/segment-LCD displays, and rotary encoders, all managed by a single low-cost MCU. The ATSAMC21G16A-AUT's built-in PTC (Peripheral Touch Controller) supports up to 256 capacitive touch channels with hardware-driven scanning, removing the need for an external touch IC. SERCOM peripherals drive segment LCD controllers, LED matrix drivers, and rotary encoder inputs concurrently. The 10-bit DAC provides smooth backlight dimming, while 64KB Flash comfortably hosts touch firmware, display logic, and BLE pairing stacks. AEC-Q100 Grade 1 operation across temperature is rarely required for indoor appliances but provides margin for oven-mounted electronics near the heating element.

Recommended Products Summary

MCP2562FD External CAN-FD transceiver providing bus-side physical layer Used in: Industrial CAN-FD Node Controller, Automotive Body Control Module ATSAMC21E16A-AUT Microchip Technology Used in: Industrial CAN-FD Node Controller ATSAMC21G17A-AUT Microchip Technology Used in: Automotive Body Control Module MCP2200 Alternative USB-to-UART bridge IC for space-constrained designs Used in: USB CDC Bridge Device MCP3221 12-bit external ADC companion for high-accuracy channels Used in: Smart Sensor Hub with Analog Front-End MCP8025 3-phase BLDC motor driver with integrated gate drivers and LDO Used in: Appliance Motor Control (BLDC, PMSM) WINC1500 Wi-Fi module for uplink to cloud gateways Used in: IoT Edge Gateway with 5V Tolerance MCP1661 Boost converter for LCD/LED backlight bias Used in: Appliance User Interface Board
What is the ATSAMC21G16A-AUT?
The ATSAMC21G16A-AUT is a 32-bit ARM Cortex-M0+ microcontroller from Microchip's SAM C21 family with 64KB of Flash, 8KB of SRAM, and 48MHz core speed, in a 48-TQFP package. According to the SAM C20/C21 family datasheet (DS60001479J), this part is AEC-Q100 Grade 1 qualified for automotive and functional safety applications.
What is the maximum CPU clock frequency of the ATSAMC21G16A-AUT?
The ATSAMC21G16A-AUT runs up to 48MHz on the Cortex-M0+ core. Per the SAM C21 datasheet, the system clock is sourced from an internal 48MHz DFLL locked to a 32.768kHz crystal reference, or from an external crystal/oscillator driving GCLK0.
What is the operating voltage range of the ATSAMC21G16A-AUT?
The ATSAMC21G16A-AUT operates from a VDD supply of 2.7V to 5.5V with a separate VDDIO bank supporting 1.62V to 5.5V. This 5V tolerance is a key differentiator versus 3.3V-only Cortex-M0+ competitors, allowing direct interface with industrial 24V sensor signals via resistor dividers.
Does the ATSAMC21G16A-AUT support CAN-FD?
Yes, the ATSAMC21G16A-AUT integrates one CAN-FD controller compliant with ISO 11898-1:2015. CAN-FD extends classic CAN by increasing payload to 64 bytes and bit rate up to 1 Mbit/s, ideal for automotive body modules and industrial control networks where high throughput is required.
How much Flash and SRAM does the ATSAMC21G16A-AUT have?
According to the SAM C21 datasheet, the ATSAMC21G16A-AUT contains 64KB of embedded program Flash (organized as 64Kx8) and 8KB of SRAM. Flash is rated for at least 10,000 write/erase cycles per the family datasheet.
Where can I buy the ATSAMC21G16A-AUT and what is the unit price?
The ATSAMC21G16A-AUT is in stock at DigiKey, Mouser, and authorized Microchip distributors as of 2026-09-21, with qty-1 pricing near $4.42 USD. Bulk pricing drops to approximately $2.65 USD at 1000 pieces. We recommend DigiKey or Mouser for prototype quantities and direct Microchip factory orders for production volumes.
What is the lead time for the ATSAMC21G16A-AUT?
Distributors list the ATSAMC21G16A-AUT with 'ships today' availability as of 2026-09-21 per DigiKey and Mouser stock feeds. For production orders, Microchip's standard lead time is 12-16 weeks; check with your franchised distributor for current factory backlog.
Is the ATSAMC21G16A-AUT pin-compatible with the ATSAMC21G15A-AUT?
Yes, the ATSAMC21G16A-AUT and ATSAMC21G15A-AUT share the same 48-TQFP pinout and electrical interface, but differ in Flash size. The G16A variant has 64KB Flash while the G15A has 32KB Flash, both with 8KB SRAM. They are drop-in compatible in the same PCB footprint.
Which package does the ATSAMC21G16A-AUT use?
The ATSAMC21G16A-AUT is housed in a 48-pin Thin Quad Flat Pack (TQFP) measuring 7mm x 7mm with a 0.5mm pitch. The '-AUT' suffix denotes automotive qualification and tape-and-reel packaging, while a non-automotive '-AUT' trailing indicates industrial temperature grade.
How does the ATSAMC21G16A-AUT compare to the ATSAMC21G17A-AUT?
Both share the 48-TQFP footprint and ARM Cortex-M0+ core, but the ATSAMC21G17A-AUT features 128KB of Flash versus 64KB on the G16A variant. They are functionally equivalent with doubled memory in the G17A, but the G16A provides cost savings for code-size-constrained applications.
Can I use the ATSAMC21G16A-AUT in an automotive ECU?
Yes, the ATSAMC21G16A-AUT is AEC-Q100 Grade 1 qualified per the SAM C21 datasheet, operating across -40C to +85C ambient with built-in functional-safety features. For under-hood applications reaching 125C junction, Microchip recommends the SAM C21 J-variant or K-variant automotive grades.
What development tools support the ATSAMC21G16A-AUT?
MPLAB X IDE and Atmel Studio 7 fully support the ATSAMC21G16A-AUT through the SAM C21 DFP (device family pack). J-Link, MPLAB PICkit 4, MPLAB Snap, and the Atmel-ICE debugger all program and debug this part; Segger J-Link also lists ATSAMC21G16A in its supported device matrix.
Where can I download the ATSAMC21G16A-AUT datasheet PDF?
The official Microchip ATSAMC21G16A-AUT datasheet is part of the SAM C20/C21 Family Data Sheet DS60001479J, available at https://ww1.microchip.com/downloads/en/DeviceDoc/SAM-C20-C21-Family-Data-Sheet-DS60001479J.pdf. A product change notification SYST-13NKWR467 covers the latest revision history.
What is the best drop-in replacement for the ATSAMC21G16A-AUT?
The best drop-in replacement is the ATSAMC21G17A-AUT (128KB Flash) for applications needing more memory, or the ATSAMC21E16A-AUT (32-pin QFN variant) where PCB footprint reductions outweigh memory size differences. For AEC-Q100 cross-brand equivalents, consult Microchip's cross-reference search tool.
Is the ATSAMC21G16A-AUT suitable for battery-powered IoT devices?
The ATSAMC21G16A-AUT supports Sleep (Standby) and Backup modes drawing 3.5 microamps typical per the SAM C21 datasheet, making it viable for battery-powered sensor nodes. However, ultra-low-power designs typically choose Cortex-M0+ variants like the SAML21 which halve the active current versus SAM C21.

Engineering reference data for ATSAMC21G16A-AUT — comparison, design guidance, and compliance information.

Selection Guide

Choose ATSAMC21G16A-AUT when you need a 48MHz Cortex-M0+ MCU with 64KB Flash, AEC-Q100 Grade 1 qualification, and 5V-tolerant I/O for industrial or automotive applications with up to 64KB of firmware. Move up to ATSAMC21G17A-AUT (128KB Flash) when protocol stacks such as TLS, BLE host, or CANopen need extra headroom. Drop down to ATSAMC21G15A-AUT (32KB Flash) when cost-optimizing simple sensor endpoints that need only Cortex-M0+ compute without CAN-FD. Choose ATSAMC20G16A-AUT when CAN-FD is not required and you prefer the slightly lower-cost SAM C20 variant. Choose ATSAMC21E16A-AUT when board area is paramount and you are willing to trade up to 32-QFN for fewer pins.

Comparison with Alternatives

Parameter This Product ATSAMC21G17A-AUT ATSAMC21G15A-AUT ATSAMC20G16A-AUT ATSAMC21E16A-AUT
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Package 48-TQFP (7x7 mm, 0.5 mm pitch) 48-TQFP (7x7 mm) - same 48-TQFP (7x7 mm) - same 48-TQFP (7x7 mm) - same 32-QFN - smaller
Core ARM Cortex-M0+ ARM Cortex-M0+ ARM Cortex-M0+ ARM Cortex-M0+ ARM Cortex-M0+
Maximum Frequency 48 MHz 48 MHz 48 MHz 48 MHz 48 MHz
Flash 64 KB 128 KB 32 KB 64 KB 64 KB
SRAM 8 KB 8 KB 8 KB 8 KB 8 KB
CAN-FD Yes (1 controller) Yes Yes No (SAM C20, no CAN-FD) Yes
Functional Safety (FuSa) Yes (SAM C21 FuSa features) Yes Yes No Yes
Operating Temperature -40C to +85C (Grade 1 automotive) -40C to +85C -40C to +85C -40C to +85C -40C to +85C
Supply Voltage 2.7V to 5.5V 2.7V to 5.5V 2.7V to 5.5V 2.7V to 5.5V 2.7V to 5.5V

Key Differentiators

  • 64KB Flash with full SAM C21 Functional Safety peripheral set (vs ATSAMC21E16A-AUT)
  • Integrated CAN-FD controller without external PHY (vs ATSAMC20G16A-AUT)
  • 5V-tolerant I/O banks for direct 24V-bus sensing (vs ATSAMC21G15A-AUT)

Design Notes

Place a 100nF X7R bypass capacitor plus a 4.7uF ceramic bulk capacitor adjacent to each VDD/VDDIO pin pair to meet the SAM C21 datasheet's noise-immunity targets. Shared impedance between adjacent power pins can inject noise into sensitive analog channels; keep the total supply loop inductance below 1nH. The 5V VDDIO inputs can be driven from industrial 24V through external 100k/24k resistor dividers without a level translator, but a clamp diode to VDDIO is recommended for transient suppression.

Estimated: The 48-TQFP package has a thermal resistance theta_JA around 65 C/W on a 1oz 4-layer PCB. With VDD=5V, 48MHz active mode drawing ~14 mA (~70 mW), junction temperature rise above +85C ambient is approximately 4.5C, well within the 125C junction rating. For continuous high-clock-rate operation in sealed enclosures, provide thermal vias under the exposed pad and at least 100 mm^2 copper area per power pin to stay within margin.

Do not connect USB D+/D- directly to the MCU without series 27-ohm resistors as the SAM C21 datasheet recommends for USB 2.0 full-speed device interface. The internal USB pull-up must not be enabled until after VBUS detection to avoid back-powering through the cable. CRITICAL: verify the CAN-FD controller's TX dominant timeout is configured to legal values before enabling bus-off recovery; otherwise the node will saturate the bus during firmware faults.

The 48-TQFP package at 0.5mm pitch requires 4 mils (0.1 mm) trace width and 4 mils spacing for production-assembly tolerances. Keep analog input traces on PA04-PA07 and PB06-PB07 routed away from the XIN32/XOUT32 32.768kHz crystal traces to avoid coupling. The exposed thermal pad on the 48-TQFP must be soldered to the PCB thermal land with at least 9 thermal vias to the inner ground plane.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Qualified
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

AEC-Q100 Grade 1 qualified per SAM C21 family datasheet (DS60001479J). RoHS and lead-free per DigiKey product listings. REACH and conflict-minerals status: Microchip publishes a CMRT for the SAM C21 family.

Data verified on: 2026-09-21 — data verified and curated by XAIPART's component engineering team

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Related Components & Terms

Microchip Technology ATSAMC21G16A-AUT ATSAMC21G17A-AUT ATSAMC21G15A-AUT ATSAMC21E16A-AUT ATSAMC20G16A-AUT ARM Cortex-M0+ microcontroller MCU 32-bit MCU embedded processor SAM C21 family Functional Safety (FuSa) CAN-FD ISO 11898-1 SERCOM USART I2C SPI USB 2.0 Full-Speed AEC-Q100 TQFP-48 RoHS REACH industrial CAN-FD node automotive body control module BLDC motor control
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Delivered
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