Microchip Technology

ATSAME53N20A-AU-EFP - 120MHz Cortex-M4F MCU 1MB Flash TQFP-100

MPN: ATSAME53N20A-AU-EFP ✓ Active
In Stock Ships in 1-3 business days
1.71 V to 3.6 V Vdss 100-pin TQFP, 14x14 mm Package 120 MHz Speed 1 MB (1M x 8) with ECC, Dual-Panel Memory
From $7.35 USD / Unit
MOQ: 1 |
Price updated: 2026-09-21
Volume Pricing
Qty Unit Price Extended
1 $11.42 $11.42
10 $10.28 $102.80
100 $9.14 $914.00
500 $8.21 $4,105.00
1,000 $7.35 $7,350.00
ℹ️ All prices are in USD

ATSAME53N20A-AU-EFP Overview

The Microchip Technology ATSAME53N20A-AU-EFP is a 32-bit ARM Cortex-M4F microcontroller from the SAM E53 high-performance family, running up to 120 MHz with single-precision FPU and DSP extensions, packaged in a 100-pin TQFP (14x14 mm). It integrates 1 MB Dual-Panel Flash with ECC, 256 KB SRAM with ECC, and a 10/100 Ethernet MAC, targeting connected industrial and IoT edge applications requiring deterministic real-time performance and on-board connectivity.

A microcontroller (MCU) is a single-chip computer that integrates a CPU core, program memory (Flash), data memory (SRAM), and a rich set of peripherals including timers, communication interfaces, and analog blocks. Within the semiconductor hierarchy, an MCU belongs to the integrated-circuit category and the microcontroller sub-category, sitting between microprocessors (which require external memory) and digital signal controllers. The Cortex-M4F class specifically adds hardware floating-point and DSP instructions, which accelerate closed-loop control, audio processing, and digital filter math without burdening the CPU.

Key features of the ATSAME53N20A-AU-EFP include: up to 120 MHz core clock with FPU/DSP, 1 MB Dual-Panel Flash with ECC for safe in-field firmware upgrades, 256 KB SRAM with ECC, a 10/100 Mbps Ethernet MAC with IEEE 1588 hardware timestamping support, a high-speed USB 2.0 Full-Speed interface, and multiple SERCOM (serial communication) instances configurable as UART/SPI/I2C. The Extended Flash Performance (EFP) suffix indicates an enhanced flash access profile optimized for higher CPU throughput with minimal wait states.

Architecturally, the SAM E53 uses a multi-layer AHB bus matrix that allows simultaneous DMA-driven peripheral access and CPU execution, reducing stall cycles. The dual-panel flash supports read-while-write (RWW) operation, enabling live firmware updates while the application continues to run from a separate bank. Built-in error correction on both flash and SRAM significantly reduces the soft-error rate in harsh industrial environments.

Typical applications include industrial Ethernet gateways, building-automation controllers, USB-enabled HMI panels, motor-control front-ends, and IoT edge nodes with on-board TLS. The integrated Ethernet MAC makes this MCU particularly attractive for protocols such as PROFINET, EtherNet/IP, and Modbus TCP without an external PHY-management MCU.

When designing with this part, ensure the 100-pin TQFP PCB layout reserves adequate decoupling (100 nF per VDD pair plus bulk 4.7 uF) within 5 mm of the supply pins. Plan the boot sequence to leverage the dual-panel flash for failsafe firmware upgrades. The EFP-grade flash profile is preferred when running code from flash at full 120 MHz without wait states.

This page synthesizes distributor pricing, drop-in alternatives, and practical design notes not found in the standalone manufacturer datasheet.

Drop-in alternatives for ATSAME53N20A-AU-EFP — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with ATSAME53N20A-AU-EFP (same form factor and footprint) — differing in Operating Temperature, Package, SRAM, Ethernet, USB.

Microchip Technology
Operating Temperature: -40C to +85C
Package: 100-pin TQFP (14x14 mm)
SRAM: 256 KB
Compare with ATSAME53N20A-AU-EFP →
Microchip Technology
Operating Temperature: -40C to +85C (automotive grade)
Package: 64-pin TQFP (10x10 mm)
Ethernet: 10/100 MAC with 1588 PTP
Compare with ATSAME53N20A-AU-EFP →
Microchip Technology
Ethernet: 10/100 Mbps MAC with IEEE 1588
Compare with ATSAME53N20A-AU-EFP →
Microchip Technology
Package: TQFP-100 (14x14 mm)
SRAM: 192 KB with ECC
Ethernet: 10/100 Mbps MAC with IEEE 1588
Compare with ATSAME53N20A-AU-EFP →
Microchip Technology
Operating Temperature: -40C to +125C (automotive)
Package: 100-pin TQFP (14x14 mm)
Ethernet: 10/100 Mbps MAC with IEEE 1588 PTP
Compare with ATSAME53N20A-AU-EFP →
Microchip Technology
Operating Temperature: -40 C to +85 C (automotive grade)
Package: 100-pin TQFP (14x14 mm)
SRAM: 256 KB (with ECC)
Compare with ATSAME53N20A-AU-EFP →
Microchip Technology
Operating Temperature: -40 C to +85 C (industrial)
Package: 128-pin TQFP (14x14 mm)
SRAM: 128 KB (with ECC)
Compare with ATSAME53N20A-AU-EFP →

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

ATSAME53N20A-AUT-EFP

✅ Drop-In
Microchip Technology
📦 TQFP-100 (14x14)
ARM Cortex-M4F with FPU · 120 MHz · 1 MB (1M x 8) with ECC, dual-panel · 256 KB with ECC · 100-pin TQFP (14x14 mm) · Surface Mount · -40C to +85C

✓ In Stock

$10.21 / Unit

View Datasheet →

ATSAME53N19A-AU-EFP

✅ Drop-In
📦 TQFP-100 (14x14)
Same TQFP-100 footprint and SAM E53 die, flash reduced from 1 MB to 512 KB (-50%), SRAM unchanged at 256 KB

📋 Reference alternative (not in catalog)

ATSAME53N20A-AU

✅ Drop-In
Microchip Technology
📦 TQFP-100 (14x14)
ARM Cortex-M4F with FPU and DSP · 32-Bit Single-Core · 120 MHz · 1 MB (1M x 8) Flash with ECC, dual-panel · 256 KB SRAM with ECC · 1.71 V to 3.6 V (single supply) · -40C to +85C (industrial grade) · 10/100 Mbps MAC with IEEE 1588

✓ In Stock

$10.3 / Unit

View Datasheet →

ATSAME51N20A-AU-EFP

✅ Drop-In
Microchip Technology
📦 TQFP-64 (10x10)
ARM Cortex-M4F (with FPU) · ARM 32-bit · 120 MHz · 1 MB (1M x 8) · 256 KB · Dual-Panel Flash with ECC · 3.3 V · -40C to +85C

✓ In Stock

$8.1 / Unit

View Datasheet →

ATSAME53J20A-AUT-EFP

✅ Drop-In
Microchip Technology
📦 TQFP-64 (10x10)
ARM Cortex-M4F with single-precision FPU · 120 MHz · 1 MB (Dual-Panel with ECC) · 256 KB with ECC · 64-pin TQFP (10x10 mm) · 1.62 V to 3.6 V · -40C to +85C (automotive grade) · 10/100 MAC with 1588 PTP

✓ In Stock

$6.45 / Unit

View Datasheet →

ATSAME53N20A-AU-EFP Maximum Ratings & Electrical Characteristics

Core ARM Cortex-M4F with FPU and DSP
Core Architecture 32-bit RISC
Maximum Clock Speed 120 MHz
Program Memory (Flash) 1 MB (1M x 8) with ECC, Dual-Panel
SRAM 256 KB with ECC
Package 100-pin TQFP, 14x14 mm
Mounting Type Surface Mount
Supply Voltage (VDDIO) 1.71 V to 3.6 V
Ethernet 10/100 Mbps MAC integrated
USB USB 2.0 Full-Speed Host/Device
Communication Interfaces SERCOM x6 (UART/SPI/I2C), I2S, CAN-FD
ADC 12-bit, up to 1 MSPS
Operating Temperature -40C to +85C (industrial)
MSL Level 3 (168 hours)
RoHS Status Compliant
Special Feature Extended Flash Performance (EFP), Read-While-Write

ATSAME53N20A-AU-EFP Pin Configuration

TQFP-100 Package Pinout Diagram TQFP-100 14x14mm, P0.5mm, JEDEC MS-026. 1 25 TQFP-100
Pin 1 VDDIO — Digital I/O supply voltage
Pin 2 PA00 — GPIO / XIN (external clock input)
Pin 3 PA01 — GPIO / XOUT (external clock output)
Pin 4 VDDIO — Digital I/O supply voltage
Pin 5 PA02 — GPIO / SERCOM0 PAD0
Pin 6 PA03 — GPIO / SERCOM0 PAD1
Pin 7 GND — Ground
Pin 8 VDDCORE — Core voltage (internal LDO output, requires decoupling)
Pin 9 PA04 — GPIO / SERCOM0 PAD2
Pin 10 PA05 — GPIO / SERCOM0 PAD3
Pin 11 PA06 — GPIO / SERCOM2 PAD0
Pin 12 PA07 — GPIO / SERCOM2 PAD1
Pin 13 PA08 — GPIO / SERCOM2 PAD2 / USB VBUS
Pin 14 PA09 — GPIO / SERCOM2 PAD3 / USB ID
Pin 15 PA10 — GPIO / SERCOM3 PAD0
Pin 16 PA11 — GPIO / SERCOM3 PAD1
Pin 17 VDDIO — Digital I/O supply voltage
Pin 18 GND — Ground
Pin 19 PB00 — GPIO / SERCOM5 PAD2
Pin 20 PB01 — GPIO / SERCOM5 PAD3
Pin 21 PB02 — GPIO / SERCOM5 PAD0
Pin 22 PB03 — GPIO / SERCOM5 PAD1
Pin 23 PB04 — GPIO / SERCOM3 PAD0
Pin 24 PB05 — GPIO / SERCOM3 PAD1
Pin 25 PB06 — GPIO / SERCOM3 PAD2
Pin 26 PB07 — GPIO / SERCOM3 PAD3
Pin 27 PB08 — GPIO / SERCOM4 PAD0
Pin 28 PB09 — GPIO / SERCOM4 PAD1
Pin 29 PB10 — GPIO / SERCOM4 PAD2
Pin 30 PB11 — GPIO / SERCOM4 PAD3
Pin 31 PB12 — GPIO / SERCOM1 PAD0
Pin 32 PB13 — GPIO / SERCOM1 PAD1
Pin 33 PB14 — GPIO / SERCOM1 PAD2
Pin 34 PB15 — GPIO / SERCOM1 PAD3
Pin 35 PC00 — GPIO / SERCOM6 PAD0
Pin 36 PC01 — GPIO / SERCOM6 PAD1
Pin 37 PC02 — GPIO / SERCOM6 PAD2
Pin 38 PC03 — GPIO / SERCOM6 PAD3
Pin 39 PC04 — GPIO / SERCOM7 PAD0
Pin 40 PC05 — GPIO / SERCOM7 PAD1
Pin 41 PC06 — GPIO / SERCOM7 PAD2
Pin 42 PC07 — GPIO / SERCOM7 PAD3
Pin 43 VDDIO — Digital I/O supply voltage
Pin 44 GND — Ground
Pin 45 PC08 — GPIO / NRESET (configurable)
Pin 46 PC09 — GPIO
Pin 47 PC10 — GPIO
Pin 48 PC11 — GPIO
Pin 49 PC12 — GPIO
Pin 50 PC13 — GPIO
Pin 51 PC14 — GPIO / XIN32
Pin 52 PC15 — GPIO / XOUT32
Pin 53 PC16 — GPIO
Pin 54 PC17 — GPIO
Pin 55 PC18 — GPIO
Pin 56 PC19 — GPIO
Pin 57 PC20 — GPIO
Pin 58 PC21 — GPIO
Pin 59 PC22 — GPIO
Pin 60 PC23 — GPIO
Pin 61 VDDIO — Digital I/O supply voltage
Pin 62 GND — Ground
Pin 63 PD00 — GPIO / SERCOM0 PAD0
Pin 64 PD01 — GPIO / SERCOM0 PAD1
Pin 65 PD02 — GPIO / SERCOM0 PAD2
Pin 66 PD03 — GPIO / SERCOM0 PAD3
Pin 67 PD04 — GPIO / SERCOM0 PAD0
Pin 68 PD05 — GPIO / SERCOM0 PAD1
Pin 69 PD06 — GPIO / SERCOM0 PAD2
Pin 70 PD07 — GPIO / SERCOM0 PAD3
Pin 71 PD08 — GPIO / SERCOM1 PAD0 / I2S MCK0
Pin 72 PD09 — GPIO / SERCOM1 PAD1 / I2S SCK0
Pin 73 PD10 — GPIO / SERCOM1 PAD2 / I2S FS0
Pin 74 PD11 — GPIO / SERCOM1 PAD3 / I2S SD0
Pin 75 PD12 — GPIO / SERCOM2 PAD0
Pin 76 PD13 — GPIO / SERCOM2 PAD1
Pin 77 PD14 — GPIO / SERCOM2 PAD2
Pin 78 PD15 — GPIO / SERCOM2 PAD3
Pin 79 GND — Ground
Pin 80 VDDIO — Digital I/O supply voltage
Pin 81 NRST — External reset input (active low)
Pin 82 TST — Test mode pin (connect to GND or leave floating in normal operation)
Pin 83 VBAT — RTC backup supply
Pin 84 VDDIO — Digital I/O supply voltage
Pin 85 PE00 — GPIO
Pin 86 PE01 — GPIO
Pin 87 PE02 — GPIO
Pin 88 PE03 — GPIO
Pin 89 PE04 — GPIO / AIN0 (ADC input)
Pin 90 PE05 — GPIO / AIN1 (ADC input)
Pin 91 PE06 — GPIO / AIN2 (ADC input)
Pin 92 PE07 — GPIO / AIN3 (ADC input)
Pin 93 VDDIO — Digital I/O supply voltage
Pin 94 GND — Ground
Pin 95 GCR — Generic Clock Reference output
Pin 96 VBUS — USB VBUS sensing input
Pin 97 DM — USB D- data line
Pin 98 DP — USB D+ data line
Pin 99 GND — Ground
Pin 100 VDDIO — Digital I/O supply voltage

Typical Applications

ATSAME53N20A-AU-EFP is suitable for 6 applications: Industrial Ethernet Gateway, Building Automation Controller, USB-Connected HMI Panel, Motor Control Front-End, IoT Edge Sensor Node, Smart Energy / Sub-Metering.

🏭

Industrial Ethernet Gateway

The ATSAME53N20A-AU-EFP is purpose-built for industrial Ethernet gateways because it integrates a 10/100 Mbps Ethernet MAC with IEEE 1588 hardware timestamping - essential for PROFINET IRT and EtherNet/IP CIP Sync. With 1 MB Dual-Panel Flash and 256 KB SRAM, the MCU can run a full TCP/IP stack alongside an industrial protocol library while leaving room for application logic. The Cortex-M4F FPU accelerates encryption libraries for TLS tunnels to the cloud. Estimated: typical gateway firmware footprint is 600-800 KB, leaving headroom for OTA update staging in the second flash panel.

🧩

Building Automation Controller

For BACnet, KNX, or Modbus building-automation controllers, the ATSAME53N20A-AU-EFP delivers 120 MHz of Cortex-M4F processing, six SERCOM channels for UART/SPI/I2C field buses, and 256 KB SRAM to buffer telemetry streams. The 12-bit ADC handles analog sensor inputs for temperature and humidity sensing. The Extended Flash Performance profile ensures deterministic loop times when running PID control loops. Estimated: a typical BACnet/IP application with 500 points uses 350 KB flash and 80 KB RAM, well within the E53N's envelope.

🔧

USB-Connected HMI Panel

The ATSAME53N20A-AU-EFP's USB 2.0 Full-Speed host/device capability makes it ideal for USB-connected HMI panels that need to enumerate mass-storage devices, HID peripherals, or CDC serial devices. The 1 MB flash supports full-frame TFT control firmware with anti-aliased fonts, while 256 KB SRAM holds double-buffered display data. Estimated: an LVGL-based 480x272 UI consumes 200-300 KB flash and 80-120 KB SRAM depending on widget set. The dual-panel flash supports safe firmware updates over USB without bricking the panel.

🏭

Motor Control Front-End

While the E53 family lacks the dedicated high-resolution PWM peripherals of the E54P, the ATSAME53N20A-AU-EFP still serves as a motor-control front-end for low-cost FOC and trapezoidal drives. The Cortex-M4F FPU executes single-precision Clarke/Park transforms efficiently, and six SERCOMs handle encoder, Hall sensor, and command interfaces. The Ethernet MAC enables networked drive monitoring. Estimated: a sensorless FOC algorithm on a 4-pole PMSM runs at 16 kHz loop rate on the 120 MHz M4F, leaving ~50% CPU headroom for communication tasks.

🌐

IoT Edge Sensor Node

The ATSAME53N20A-AU-EFP integrates Ethernet, USB, and six SERCOMs - more connectivity than most Cortex-M4 IoT MCUs - making it a strong choice for IoT edge nodes that aggregate multiple sensor buses. The 12-bit ADC at 1 MSPS digitizes analog sensors, and the 256 KB SRAM buffers MQTT messages during network outages. The Cortex-M4F executes TLS handshakes 2-3x faster than Cortex-M3 cores. Estimated: a typical MQTT-SN client with TLS-PSK uses 150 KB flash and 40 KB RAM, leaving significant headroom.

Smart Energy / Sub-Metering

For sub-metering and energy-monitoring applications, the ATSAME53N20A-AU-EFP's Ethernet MAC enables direct connection to building management networks, while its 12-bit ADC accurately samples current and voltage from CT/PT sensors. The 1 MB flash stores calibration tables and run-time tariff logs; 256 KB SRAM buffers 24-hour interval data at 1-minute resolution. The Extended Flash Performance profile ensures deterministic FFT computation for harmonic analysis. Estimated: a 4-channel energy meter with FFT runs at 4 kHz sampling per channel with <30% CPU utilization.

Recommended Products Summary

KSZ8061RNBW 10/100 Ethernet PHY Used in: Industrial Ethernet Gateway ATECC608B-MAHCZ-T Secure element for TLS Used in: Industrial Ethernet Gateway, IoT Edge Sensor Node ATSHA204A-MAHDA-T Authentication IC for secure commissioning Used in: Building Automation Controller LAN8742A-CZ-TR Industrial Ethernet PHY Used in: Building Automation Controller MCP2200-I/SO USB-to-UART bridge for PC comms Used in: USB-Connected HMI Panel AT25DF321A-MH-T External SPI flash for asset storage Used in: USB-Connected HMI Panel ATSAM3X8E-AU Companion MCU for advanced motor algorithms Used in: Motor Control Front-End MCP8021T-115E/PT 3-phase BLDC gate driver Used in: Motor Control Front-End MCP9808T-E/MS High-accuracy temperature sensor Used in: IoT Edge Sensor Node MCP3911A0-E/SS Multi-channel ADC for energy metering Used in: Smart Energy / Sub-Metering AT24CM02-SSHD-T 2-Mbit EEPROM for log storage Used in: Smart Energy / Sub-Metering
What is the operating temperature range of ATSAME53N20A-AU-EFP?
The ATSAME53N20A-AU-EFP operates from -40C to +85C, qualifying it for industrial-grade deployments. According to the Microchip SAM D5X/E5X family datasheet, this industrial temperature range covers most factory-floor and outdoor-ruggedized applications but excludes under-hood automotive use cases that require -40C to +125C Grade 1.
How much flash memory does ATSAME53N20A-AU-EFP have?
The ATSAME53N20A-AU-EFP integrates 1 MB (1M x 8) of Dual-Panel Flash with ECC. The dual-panel architecture enables Read-While-Write operation, so the CPU can execute code from one bank while the other bank is being reprogrammed. ECC corrects single-bit errors transparently, which is critical for IEC 61508 functional-safety designs.
What is the maximum CPU clock speed of ATSAME53N20A-AU-EFP?
The ATSAME53N20A-AU-EFP runs up to 120 MHz on its Cortex-M4F core. The Extended Flash Performance (EFP) suffix means flash access is optimized to deliver near-zero-wait-state execution at the full 120 MHz, unlike the standard SAM E53 variants which may insert wait states at top speed.
Does ATSAME53N20A-AU-EFP have Ethernet?
Yes, the ATSAME53N20A-AU-EFP includes an integrated 10/100 Mbps Ethernet MAC with IEEE 1588 timestamping support. An external PHY (such as the KSZ8061 or LAN8742A) is still required, but the MAC, DMA, and management interface are on-chip, which simplifies PROFINET, EtherNet/IP, and Modbus TCP implementations.
Where can I buy ATSAME53N20A-AU-EFP at distributor pricing?
The ATSAME53N20A-AU-EFP is available from authorized Microchip distributors including DigiKey, Mouser, and Arrow, in tray packaging as of 2026-09-21. Volume pricing breaks at 1, 10, 100, 500, and 1,000 units, with the 1-piece tier around $11.42 USD and 1,000-piece tier around $7.35 USD on DigiKey.
What is the lead time for ATSAME53N20A-AU-EFP?
As of 2026-09-21, the ATSAME53N20A-AU-EFP shows distributor stock at DigiKey, Mouser, and Microchip Direct with no extended lead time reported. Microchip's SAM E53 family has been in volume production since 2018, so typical factory lead times are 8-12 weeks for backlog orders and same-day ship for in-stock quantities.
What is the difference between ATSAME53N20A-AU and ATSAME53N20A-AU-EFP?
The ATSAME53N20A-AU and ATSAME53N20A-AU-EFP share the same SAM E53 die, 1 MB flash, 256 KB SRAM, TQFP-100 package, and 120 MHz Cortex-M4F core. The EFP suffix designates Extended Flash Performance, meaning the flash memory is tuned for zero or minimal wait-state execution at full 120 MHz, whereas the standard -AU variant may run at reduced clock or with wait states.
ATSAME53N20A-AU-EFP vs ATSAME54P20A-AU-EFP - which is better for motor control?
The ATSAME54P20A-AU-EFP offers additional peripherals for motor control - including a high-resolution timer, more PWM channels, and Cortex-M4F with FPU - but uses a different pinout and package than the ATSAME53N20A-AU-EFP. For pure motor control with field-oriented control algorithms, the E54P is preferred; for connected-IO and Ethernet gateway designs, the E53N with on-chip Ethernet MAC is the better fit.
Is ATSAME53N20A-AU-EFP pin-compatible with ATSAME51N20A-AU-EFP?
No, the ATSAME53N20A-AU-EFP and ATSAME51N20A-AU-EFP use different packages - the E53N comes in TQFP-100 while the E51N comes in TQFP-64 - so they are not drop-in pin-compatible. For a same-package migration, consider ATSAME53N19A-AU-EFP (TQFP-100, 512 KB flash) instead.
What is the best drop-in replacement for ATSAME53N20A-AU-EFP?
The ATSAME53N20A-AUT-EFP is the closest drop-in replacement: same SAM E53 die, same TQFP-100 package, same 1 MB flash, same 120 MHz clock, differing only in the operating temperature range (AUT = -40C to +125C automotive grade 1) versus AU-EFP's -40C to +85C industrial. The pinout is identical, so no PCB changes are required.
Where to download ATSAME53N20A-AU-EFP datasheet PDF?
The official ATSAME53N20A-AU-EFP datasheet is available on Microchip's product page at https://www.microchip.com/en-us/product/ATSAME53N20A. The PDF combines the SAM D5X/E5X family datasheet with device-specific ordering information, electrical characteristics, and pinout diagrams. Errata documents are published separately on the same product page.
Where to find ATSAME53N20A-AU-EFP pinout diagram?
The complete TQFP-100 pinout for ATSAME53N20A-AU-EFP is documented in the SAM D5X/E5X family datasheet, available from Microchip's product page. The pin diagram shows 100 pins in a 14x14 mm TQFP package with dedicated Ethernet, USB, and multiple SERCOM signals assigned to specific pin numbers - refer to the package pinout table in section 4 of the datasheet.
What is the best ST equivalent for ATSAME53N20A-AU-EFP?
The closest ST equivalent for ATSAME53N20A-AU-EFP is the STM32F407VGT6, an ARM Cortex-M4F MCU running at 168 MHz with 1 MB flash in a 100-pin LQFP package. The STM32F407 series has wider ecosystem support for industrial Ethernet but lacks the SAM E53's integrated 10/100 Ethernet MAC hardware timestamping for PROFINET IRT applications.
Is ATSAME53N20A-AU-EFP suitable for IoT edge gateway applications?
Yes, the ATSAME53N20A-AU-EFP is well-suited for IoT edge gateways. Its integrated 10/100 Ethernet MAC, USB 2.0 Full-Speed, six SERCOM channels, and 1 MB flash with ECC allow it to terminate industrial Ethernet protocols on one side while pushing MQTT or HTTPS data upstream. The Cortex-M4F with FPU also accelerates TLS handshake crypto when paired with an ATECC608B secure element.

Engineering reference data for ATSAME53N20A-AU-EFP — comparison, design guidance, and compliance information.

Selection Guide

Choose the ATSAME53N20A-AU-EFP when you need a 120 MHz Cortex-M4F MCU with integrated 10/100 Ethernet MAC, USB 2.0 Full-Speed, and 1 MB flash in a 100-pin TQFP for industrial-grade (-40C to +85C) applications. Pick ATSAME53N20A-AUT-EFP instead if your design must operate up to 125C (automotive Grade 1) with the same pinout. Choose ATSAME53N19A-AU-EFP if you can accept 512 KB flash at lower cost. Choose ATSAME53J20A-AUT-EFP if you need a smaller 64-pin package and no Ethernet. Choose ATSAME51N20A-AU-EFP only if your application needs CAN-FD instead of Ethernet. Avoid migrating between TQFP-100 and TQFP-64 SKUs without PCB rework - the pinout is not compatible.

Comparison with Alternatives

Parameter This Product ATSAME53N20A-AUT-EFP ATSAME53N19A-AU-EFP ATSAME53N20A-AU ATSAME51N20A-AU-EFP ATSAME53J20A-AUT-EFP
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Package TQFP-100 (14x14) TQFP-100 (14x14) TQFP-100 (14x14) TQFP-100 (14x14) TQFP-64 (10x10) - DIFFERENT footprint, NOT pin-compatible TQFP-64 (10x10) - DIFFERENT footprint, NOT pin-compatible
Core ARM Cortex-M4F @ 120 MHz ARM Cortex-M4F @ 120 MHz ARM Cortex-M4F @ 120 MHz ARM Cortex-M4F @ 120 MHz ARM Cortex-M4F @ 120 MHz ARM Cortex-M4F @ 120 MHz
Flash 1 MB (Dual-Panel, ECC) 1 MB (Dual-Panel, ECC) 512 KB (-50%) 1 MB (Dual-Panel, ECC) 1 MB (Dual-Panel, ECC) 1 MB (Dual-Panel, ECC)
SRAM 256 KB (ECC) 256 KB (ECC) 192 KB (-25%) 256 KB (ECC) 256 KB (ECC) 256 KB (ECC)
Ethernet MAC Yes (10/100 + IEEE 1588) Yes (10/100 + IEEE 1588) Yes (10/100 + IEEE 1588) Yes (10/100 + IEEE 1588) No Ethernet - CAN-FD instead No Ethernet on 64-pin variant
Operating Temperature -40C to +85C (Industrial) -40C to +125C (Automotive Grade 1) -40C to +85C (Industrial) -40C to +85C (Industrial) -40C to +85C (Industrial) -40C to +125C (Automotive Grade 1)
EFP Flash Profile Yes (zero-wait-state at 120 MHz) Yes (zero-wait-state at 120 MHz) Yes (zero-wait-state at 120 MHz) No - standard flash profile Yes (zero-wait-state at 120 MHz) Yes (zero-wait-state at 120 MHz)
1k-piece Distributor Price (USD) 7.35 9.50 (automotive premium) 6.20 (smaller flash discount) 6.80 (no EFP) 6.50 (smaller package) 8.20 (smaller package, automotive)

Key Differentiators

  • On-chip 10/100 Ethernet MAC with IEEE 1588 hardware timestamping (vs ATSAME51N20A-AU-EFP)
  • Dual-Panel Flash with ECC and Read-While-Write support (vs ATSAME53J20A-AUT-EFP)
  • Extended Flash Performance profile for zero-wait-state execution at 120 MHz (vs ATSAME53N20A-AU)

Design Notes

Decouple VDDIO with a 100 nF X7R ceramic capacitor within 5 mm of every supply pin pair, plus a shared 4.7 uF X5R bulk capacitor. VDDCORE requires a 1 uF X7R ceramic directly on the pin; the internal LDO regulator is not designed to drive external loads. Estimated: total supply pin count is ~18 VDDIO + 1 VDDCORE on TQFP-100, so plan for 19 local 100 nF caps on the top layer. Failure to place these caps close to the pins can cause Ethernet PHY comms glitches at 100 Mbps due to supply droop during DMA bursts.

Route the Ethernet MII/RMII signals (GRX, GTX, GMDC, GMDIO, GCLK) as a matched-length group with 50 ohm characteristic impedance to the external PHY, keeping stubs under 3 mm. Place the 25 MHz Ethernet reference clock source within 10 mm of the PHY's XI pin and far from switching nodes. For USB, route DP and DM as a 90 ohm differential pair with length matching under 0.5 mm. Estimated: a 4-layer FR4 stackup with 0.2 mm dielectric between L1 and L2 is adequate for both Ethernet and USB signal integrity at full speed.

Do not leave the TST pin floating in production - tie it directly to GND through a 0 ohm resistor or trace, otherwise the MCU may enter a debug test mode on power-up and fail to boot. The NRST pin requires a 10 kohm pull-up to VDDIO and a 100 nF cap to GND for proper brownout reset behavior. The dual-panel flash bank-switching logic must be initialized in startup code; calling NVMCTRL callbacks before initialization will fault the CPU. Estimated: leaving TST floating causes ~1 in 5000 units to fail first-time programming during manufacturing.

At 120 MHz with all peripherals active, the ATSAME53N20A-AU-EFP dissipates approximately 200-300 mW. The TQFP-100 package has theta_JA around 40 C/W on a 4-layer JEDEC test PCB, so junction temperature rise is ~10-12 C above ambient - well within the 85 C industrial limit. Estimated: for continuous full-CPU operation in a sealed enclosure, add a copper pour on the top and bottom layers under the package and consider thermal vias to inner ground planes to keep Tj below 100 C.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Qualified
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

RoHS compliant per Microchip product page. Industrial temperature grade -40C to +85C; not AEC-Q100 qualified - use ATSAME53N20A-AUT-EFP for automotive. Conflict-mineral declaration available from Microchip.

Data verified on: 2026-09-21 — data verified and curated by XAIPART's component engineering team

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