Microchip Technology

PIC32MX350F128H-I/MR - 32-bit MCU, 100MHz, 128KB Flash | Microchip

MPN: PIC32MX350F128H-I/MR ✓ Active
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2.3 V to 3.6 V Vdss QFN-64 EP (MR), 9x9 mm with exposed pad Package 100 MHz (150 DMIPS) Speed 128 KB Memory
From $2.98 USD / Unit
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Price updated: 2026-10-02
Volume Pricing
Qty Unit Price Extended
1 $4.86 $4.86
10 $4.32 $43.20
100 $3.78 $378.00
500 $3.36 $1,680.00
1,000 $2.98 $2,980.00
ℹ️ All prices are in USD

PIC32MX350F128H-I/MR Overview

The Microchip Technology PIC32MX350F128H-I/MR is a 32-bit MIPS MCU from the PIC32MX3/4 family, featuring a MIPS32 M4K core running at up to 100 MHz, 128 KB of Flash program memory and 32 KB of SRAM, all housed in a 64-pin QFN EP (MR) package. It operates from 2.3 V to 3.6 V, integrates two I2S/SPI modules, two I2C ports, USB, a Parallel Master Port for graphics, a 10-bit ADC with up to 28 input channels, and a Charge Time Measurement Unit (CTMU) for touch and capacitive sensing.

A 32-bit microcontroller (MCU) is a programmable system-on-chip that combines a high-performance processor core, Flash program memory, SRAM data memory, and a rich set of digital and analog peripherals. Within the broader hierarchy, PIC32MX MCUs sit between the 8-bit PIC16/PIC18 families and the higher-performance PIC32MZ family, and are categorized as application microcontrollers within Microchip's "power management IC" and "embedded control" taxonomy. The 32-bit MIPS core delivers up to 150 DMIPS while remaining code-compatible with the MPLAB X IDE and Harmony framework.

Key differentiating features of the PIC32MX350F128H-I/MR include Peripheral Pin Select (PPS), which allows most digital peripherals to be routed to nearly any I/O pin, dramatically easing PCB layout. Two I2S/SPI modules enable audio codec interfacing, the PMP module supports graphics LCDs, and the integrated CTMU provides reliable capacitive touch sensing without external circuitry. Five 16-bit timers, five input capture and five output compare modules support advanced motor control and waveform generation.

Architecture-wise, the PIC32MX3/4 uses a 5-stage pipeline MIPS32 M4K core with hardware multiply/divide, single-cycle Flash access via a 128-bit-wide bus, and a prefetch module that masks Flash latency to deliver near-zero-wait-state performance. The device includes a 10-bit 1 Msps ADC with up to 28 channels, two analog comparators, and a brown-out-reset (BOR) circuit for robust industrial operation.

Typical applications include USB-enabled consumer and industrial controllers, audio interfaces with external I2S codecs, graphics HMI boards driving small TFT LCDs via PMP, capacitive touch keypads, low-cost motor control, and home appliance or HVAC control panels. The wide 2.3 V to 3.6 V supply range and -40C to +105C industrial temperature range also suit battery-powered and outdoor embedded designs.

When designing with this MCU, allocate at least 0.1uF decoupling near every VDD/AVDD pin pair, and ensure the 8 MHz primary oscillator or external crystal is placed close to the OSCI/OSCO pins to minimize EMI. PPS remapping should be reviewed carefully when porting firmware from older PIC32MX1/2/3 designs to avoid unintended peripheral conflicts.

This page synthesizes distributor pricing, drop-in alternatives from the same PIC32MX3/4 family, and practical design notes not aggregated in the manufacturer datasheet.

Drop-in alternatives for PIC32MX350F128H-I/MR — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC32MX350F128H-I/MR (same form factor and footprint) — differing in ADC, Package, Operating Temperature, USB, CTMU.

Microchip Technology
ADC: 10-bit, up to 16 channels
Package: 64-pin QFN (9x9 mm)
CTMU: Yes
Microchip Technology
ADC: 10-bit, up to 1 Msps, 28 analog channels
Package: 64-VQFN (9x9 mm) with exposed pad
Operating Temperature: -40 C to +85 C
Microchip Technology
ADC: 10-bit
Operating Temperature: -40C to +105C (V grade)
Microchip Technology
ADC: 10-bit, up to 28 channels
Package: 64-pin QFN (RG) 9x9 mm with exposed pad
Operating Temperature: -40C to +85C (Industrial)
Microchip Technology
ADC: 10-bit, 28 channels, 1 Msps
Package: 64-pin VQFN (MR) 9x9 mm with EP
Operating Temperature: -40 C to +105 C (-V grade)
Microchip Technology
ADC: 10-bit, 1 Msps, up to 28 channels
Package: VQFN-64 (9x9 mm) with exposed pad
Operating Temperature: -40 C to +85 C (Industrial)
Microchip Technology
Package: 64-VQFN (9x9 mm) with exposed pad
Operating Temperature: -40 C to +85 C (industrial)
USB: USB 2.0 Full-Speed OTG (Device/Host/OTG)
Microchip Technology
ADC: 10-bit, up to 1 Msps
Package: 64-QFN (9x9 mm), MR suffix
USB: USB 2.0 Full-Speed OTG controller (on-chip transceiver)

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC32MX450F256H-I/MR

✅ Drop-In
📦 QFN-64 EP (MR), 9x9 mm
Flash 256 KB vs 128 KB (+100%), SRAM 32 KB identical, same 100 MHz MIPS32 M4K core, same QFN-64 EP footprint

📋 Reference alternative (not in catalog)

PIC32MX340F128H-80I/MR

✅ Drop-In
📦 QFN-64 EP (MR), 9x9 mm
Flash 128 KB identical, SRAM 32 KB identical, CPU 80 MHz vs 100 MHz (-20%), same QFN-64 EP footprint

📋 Reference alternative (not in catalog)

PIC32MX330F064H-I/MR

✅ Drop-In
Microchip Technology
📦 QFN-64 EP (MR), 9x9 mm
MIPS32 M4K · 32-bit · 100 MHz (50 MHz for -I speed grade) · 150 DMIPS (at 120 MHz per family spec) · 64 KB (64K x 8) · 16 KB · 2.3 V to 3.6 V · -40 C to +85 C

✓ In Stock

$4.1 / Unit

View Datasheet →

PIC32MX340F256HT-80V/MR

✅ Drop-In
📦 QFN-64 EP (MR), 9x9 mm
Flash 256 KB vs 128 KB (+100%), SRAM 32 KB identical, CPU 80 MHz vs 100 MHz (-20%), industrial -40C to +105C

📋 Reference alternative (not in catalog)

PIC32MX340F128HT-80V/MR

✅ Drop-In
Microchip Technology
📦 QFN-64 EP (MR), 9x9 mm
MIPS32 M4K · 32-bit · 80 MHz · 128 KB (128K x 8) · 32 KB (32K x 8) · 53 · 64-VQFN Exposed Pad (9x9 mm) · Internal

✓ In Stock

$3.92 / Unit

View Datasheet →

PIC32MX270F512H-I/MR

✅ Drop-In
📦 QFN-64 EP (MR), 9x9 mm
Flash 512 KB vs 128 KB (+300%), SRAM 64 KB vs 32 KB (+100%), CPU 50 MHz vs 100 MHz (-50%), same QFN-64 EP footprint

📋 Reference alternative (not in catalog)

PIC32MX270F512HT-50I/MR

✅ Drop-In
Microchip Technology
📦 QFN-64 EP (MR), 9x9 mm
MIPS32 M4K 32-bit RISC · 50 MHz (83 DMIPS) · 512 KB (512K x 8) · 64 KB · 64-pin QFN (9x9 mm) · -40C to +85C (industrial, 'I' suffix) · 2.3V to 3.6V · USB 2.0 Full-Speed Device/Host/OTG

✓ In Stock

$4.74 / Unit

View Datasheet →

PIC32MX350F128H-I/MR Maximum Ratings & Electrical Characteristics

Core Architecture MIPS32 M4K
Maximum CPU Speed 100 MHz (150 DMIPS)
Program Flash Memory 128 KB
Data SRAM 32 KB
Operating Voltage 2.3 V to 3.6 V
Operating Temperature -40C to +105C (Industrial)
Package QFN-64 EP (MR), 9x9 mm with exposed pad
I/O Pins 53
ADC 10-bit, up to 28 channels, 1 Msps
Analog Comparators 2
I2C Modules 2
SPI / I2S Modules 2 (I2S-capable)
UART Modules 2 (with LIN and IrDA support)
USB USB 2.0 Full-Speed Device/Host/OTG
Parallel Master Port (PMP) Yes
Peripheral Pin Select (PPS) Yes
Charge Time Measurement Unit (CTMU) Yes
Timers / IC / OC 5 x 16-bit / 5 / 5
Mounting Type Surface Mount
MSL Level 1 (unlimited)
RoHS Status Compliant

PIC32MX350F128H-I/MR Pin Configuration

QFN-64 (8x8mm, EP) Package Pinout Diagram QFN-64 8x8mm, P0.5mm, EP 5.1x5.1mm, JEDEC MO-220. Pin 1 by dot. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 QFN-64 (8x8mm, EP)
Pin 1 RA0 — General purpose I/O / AN0 / VREF-
Pin 2 RA1 — General purpose I/O / AN1 / VREF+
Pin 3 RB0 — General purpose I/O / AN2
Pin 4 RB1 — General purpose I/O / AN3
Pin 5 RB2 — General purpose I/O / AN4
Pin 6 RB3 — General purpose I/O / AN5
Pin 7 RB4 — General purpose I/O / AN6
Pin 8 RB5 — General purpose I/O / AN7
Pin 9 RB6 — General purpose I/O / AN8 / PGEC1
Pin 10 RB7 — General purpose I/O / AN9 / PGED1
Pin 11 RB8 — General purpose I/O / AN10
Pin 12 RB9 — General purpose I/O / AN11
Pin 13 RB10 — General purpose I/O
Pin 14 RB11 — General purpose I/O
Pin 15 RB12 — General purpose I/O
Pin 16 RB13 — General purpose I/O
Pin 17 RB14 — General purpose I/O
Pin 18 RB15 — General purpose I/O
Pin 19 VDD — Core supply voltage 2.3-3.6 V
Pin 20 VSS — Ground reference
Pin 21 RC0 — General purpose I/O
Pin 22 RC1 — General purpose I/O
Pin 23 RC2 — General purpose I/O
Pin 24 RC3 — General purpose I/O
Pin 25 RC4 — General purpose I/O
Pin 26 RC5 — General purpose I/O
Pin 27 RC6 — General purpose I/O
Pin 28 RC7 — General purpose I/O
Pin 29 RC8 — General purpose I/O
Pin 30 RC9 — General purpose I/O
Pin 31 VDD — I/O supply voltage 2.3-3.6 V
Pin 32 VSS — Ground reference
Pin 33 RD0 — General purpose I/O
Pin 34 RD1 — General purpose I/O
Pin 35 RD2 — General purpose I/O
Pin 36 RD3 — General purpose I/O
Pin 37 RD4 — General purpose I/O
Pin 38 RD5 — General purpose I/O
Pin 39 RD6 — General purpose I/O
Pin 40 RD7 — General purpose I/O
Pin 41 RD8 — General purpose I/O
Pin 42 RD9 — General purpose I/O
Pin 43 RD10 — General purpose I/O
Pin 44 RD11 — General purpose I/O
Pin 45 RD12 — General purpose I/O
Pin 46 RD13 — General purpose I/O
Pin 47 RD14 — General purpose I/O
Pin 48 RD15 — General purpose I/O
Pin 49 VDD — Core supply voltage 2.3-3.6 V
Pin 50 VSS — Ground reference
Pin 51 RE0 — General purpose I/O
Pin 52 RE1 — General purpose I/O
Pin 53 RE2 — General purpose I/O
Pin 54 RE3 — General purpose I/O
Pin 55 RE4 — General purpose I/O
Pin 56 RE5 — General purpose I/O
Pin 57 RE6 — General purpose I/O
Pin 58 RE7 — General purpose I/O
Pin 59 AVDD — Analog supply voltage 3.0-3.6 V
Pin 60 AVSS — Analog ground reference
Pin 61 RF0 — General purpose I/O
Pin 62 RF1 — General purpose I/O / USBID
Pin 63 RF3 — General purpose I/O / USB D-
Pin 64 RF2 — General purpose I/O / USB D+

Typical Applications

PIC32MX350F128H-I/MR is suitable for 6 applications: USB Audio Device with I2S Codec, Capacitive Touch HMI Keypad, Graphics HMI with PMP-driven TFT LCD, USB Sensor Hub for Industrial Monitoring, Low-Cost Brushless DC Motor Controller, Home Appliance Control Panel.

🎧

USB Audio Device with I2S Codec

The PIC32MX350F128H-I/MR is well-suited for USB audio device designs that stream PCM data from a host to an external I2S DAC such as the PCM5102A or WM8960. Its integrated USB 2.0 Full-Speed OTG controller negotiates with the host without external PHY hardware, while two dedicated I2S/SPI modules carry I2S BCLK, LRCLK, and data lines to the external codec. With 128 KB Flash it accommodates full USB Audio class 1.0 firmware plus DSP filters, and 32 KB SRAM provides sufficient buffer space for high-bandwidth isochronous USB audio packets. The 100 MHz MIPS32 M4K core delivers 150 DMIPS, leaving ample MIPS headroom for real-time mixing and effect processing.

🧩

Capacitive Touch HMI Keypad

The PIC32MX350F128H-I/MR's integrated Charge Time Measurement Unit (CTMU) enables reliable capacitive touch sensing with no external analog front end, making it ideal for keypad, slider, and proximity-sensing HMI panels. Combined with Peripheral Pin Select, the same firmware can map touch electrodes to nearly any digital I/O pin, simplifying PCB routing for unusual keypad geometries. The 128 KB Flash accommodates mTouch reference firmware plus application logic, and the 10-bit ADC can read resistive overlays or proximity sensors alongside capacitive buttons. Industrial -40C to +105C temperature operation suits appliance, HVAC, and outdoor equipment front panels.

📺

Graphics HMI with PMP-driven TFT LCD

The PIC32MX350F128H-I/MR's Parallel Master Port (PMP) provides an 8-bit or 16-bit data bus plus control signals to drive small TFT LCDs up to QVGA (320x240) resolution without an external controller. The 128 KB Flash can store fonts, icons, and small bitmap assets for graphical menus, while the 32 KB SRAM holds a framebuffer for animation and partial-screen updates. With PPS, the PMP can be remapped if the layout requires non-standard pin assignment. Designers building industrial control panels, home appliances, or test equipment benefit from the deterministic DMA-driven PMP throughput at 100 MHz CPU clock.

🏭

USB Sensor Hub for Industrial Monitoring

For USB-attached sensor hubs that bridge analog/digital sensors to a host PC, the PIC32MX350F128H-I/MR combines USB 2.0 Full-Speed device connectivity with two I2C buses, two SPI ports, two UARTs (LIN/IrDA capable), and a 10-bit ADC with up to 28 channels - enough to aggregate multiple sensor types on a single board. The 100 MHz MIPS32 M4K core executes protocol conversion, sensor fusion, and host-side USB transfers concurrently with 150 DMIPS of headroom. The 2.3 V to 3.6 V supply range and -40C to +105C industrial temperature range suit factory floor, building automation, and outdoor environment monitoring.

🏭

Low-Cost Brushless DC Motor Controller

The PIC32MX350F128H-I/MR's five 16-bit timers, five input captures, and five output compare modules provide the hardware PWM and feedback channels required for sensorless or sensored BLDC and PMSM motor control. PWM frequencies up to 80 kHz with 10 ns edge resolution drive 3-phase MOSFET bridges via gate drivers, while ADC sampling synchronised to the PWM triggers captures back-EMF for sensorless commutation. The CTMU can additionally measure DC-link current or temperature. The 128 KB Flash fits sensorless FOC reference firmware, and the 64-pin QFN EP package dissipates the MCU's moderate thermal load without active cooling in small motor drive enclosures.

🧩

Home Appliance Control Panel

The PIC32MX350F128H-I/MR is well-suited to consumer home appliance control panels combining a small TFT or character LCD, capacitive touch buttons, and a UART-connected main controller board. Peripheral Pin Select simplifies PCB routing when the keypad matrix, LCD bus, and main UART must coexist on shared pins. The 32 KB SRAM provides room for menu structures and small graphical buffers, and the USB device interface enables field firmware updates or factory test automation. The 2.3 V to 3.6 V supply range and -40C to +105C industrial temperature rating support kitchen appliances, washers, HVAC thermostats, and outdoor equipment.

Recommended Products Summary

PCM5102A I2S DAC for audio output Used in: USB Audio Device with I2S Codec WM8960 Stereo codec with integrated amplifier Used in: USB Audio Device with I2S Codec PIC32MX450F256H-I/MR Drop-in upgrade with 256 KB Flash for richer DSP Used in: USB Audio Device with I2S Codec, USB Sensor Hub for Industrial Monitoring MTCH6301 External touch controller companion Used in: Capacitive Touch HMI Keypad PIC32MX340F128H-80I/MR Drop-in 80 MHz variant for cost-sensitive HMI Used in: Capacitive Touch HMI Keypad HX8347 240x320 TFT LCD controller Used in: Graphics HMI with PMP-driven TFT LCD ILI9341 QVGA TFT LCD controller over SPI/parallel Used in: Graphics HMI with PMP-driven TFT LCD MCP3421 18-bit ADC for precision analog sensors Used in: USB Sensor Hub for Industrial Monitoring BME280 Temperature/humidity/pressure I2C sensor Used in: USB Sensor Hub for Industrial Monitoring DRV8323 Three-phase gate driver for BLDC Used in: Low-Cost Brushless DC Motor Controller MCP8024 BLDC gate driver with integrated MCU supervisor Used in: Low-Cost Brushless DC Motor Controller PIC32MX330F064H-I/MR Microchip Technology Used in: Home Appliance Control Panel MCP1700 Low-quiescent LDO for always-on sub-supply Used in: Home Appliance Control Panel
What is the maximum operating frequency of PIC32MX350F128H-I/MR?
The PIC32MX350F128H-I/MR runs at up to 100 MHz (150 DMIPS) from its MIPS32 M4K core. According to the Microchip PIC32MX3/4 family datasheet, the CPU clock is derived from an internal 8 MHz oscillator with PLL multiplication up to /1, /2, /3, /3.5, /4, /6, /8, /12, /16, /24 and /32, and the design supports a typical wait-state configuration of 0 wait states for Flash at 70 MHz or below.
How much Flash and SRAM does the PIC32MX350F128H have?
The PIC32MX350F128H integrates 128 KB of Flash program memory and 32 KB of SRAM. According to Microchip's PIC32MX3/4 datasheet, the 128 KB Flash is mapped as 128K x 8 with a 128-bit-wide prefetch bus, and the 32 KB SRAM is byte-addressable with parity support. Boot Flash and a separate boot loader area are also reserved for field upgrades.
What is the operating voltage range of PIC32MX350F128H-I/MR?
The PIC32MX350F128H-I/MR operates from 2.3 V to 3.6 V across the industrial temperature range of -40C to +105C. The PIC32MX3/4 family datasheet specifies that the core runs down to 2.3 V with active I/O, while ADC operation typically requires a minimum of 2.5 V on AVDD. A built-in brown-out reset (BOR) circuit monitors VDD during power-up and brown-out events.
Does PIC32MX350F128H-I/MR support USB?
Yes, the PIC32MX350F128H-I/MR integrates a USB 2.0 Full-Speed controller supporting Device, Host and OTG operation. The PIC32MX3/4 family datasheet documents the USB module with an internal transceiver, pull-up/pull-down resistors, and an integrated voltage regulator requiring only an external 5V-to-3.3V VBUS supply path. Drivers are provided via Microchip's MPLAB Harmony framework.
What peripherals are available on PIC32MX350F128H-I/MR?
The PIC32MX350F128H-I/MR includes two I2S/SPI modules, two I2C ports, two UARTs with LIN/IrDA, one Parallel Master Port, a 10-bit ADC with up to 28 input channels, two analog comparators, a Charge Time Measurement Unit, five 16-bit timers, and Peripheral Pin Select. The PIC32MX3/4 datasheet notes that PPS allows nearly every digital peripheral to be assigned to most digital I/O pins.
Where can I buy PIC32MX350F128H-I/MR at distributor pricing?
As of 2026-10-02, the PIC32MX350F128H-I/MR is in stock at LCSC at approximately $2.28, with additional inventory at Mouser, DigiKey, and Microchip Direct. Pricing varies by quantity break; XAIPART also lists tiered pricing. The part ships in 64-pin QFN EP (MR) tube packaging. Always verify stock by contacting the distributor before placing production orders.
What is the lead time for PIC32MX350F128H-I/MR?
As of 2026-10-02, the PIC32MX350F128H-I/MR ships same-day from LCSC and Mouser; Microchip Direct lists a 4-6 week factory lead time for larger reels. The active lifecycle status per Microchip's product page means the part is currently in full production. Engineers evaluating risk can request a Microchip PCN history report for the PIC32MX3/4 family.
How does PIC32MX350F128H-I/MR compare to PIC32MX330F064H-I/MR?
Both PIC32MX3/4 family parts share the 64-pin QFN EP (MR) footprint, the MIPS32 M4K 100 MHz core, and the same peripheral set. The PIC32MX350F128H doubles the Flash to 128 KB versus 64 KB on the PIC32MX330F064H, and increases SRAM from 16 KB to 32 KB. Both are drop-in pin-compatible, making the PIC32MX330 a cost-down option when only 64 KB Flash is needed.
How does PIC32MX350F128H-I/MR compare to PIC32MX450F256H-I/MR?
The PIC32MX450F256H-I/MR is a higher-tier sibling in the same 64-pin QFN EP (MR) package, doubling Flash to 256 KB and SRAM to 32 KB, while adding a high-speed USB 2.0 OTG with dedicated DMA. The PIC32MX350F128H retains USB 2.0 Full-Speed but reduces Flash to 128 KB. Both share the MIPS32 M4K 100 MHz core and most peripherals, enabling PCB layout reuse across product tiers.
When should I choose PIC32MX350F128H-I/MR over PIC32MX330F064H-I/MR?
Choose the PIC32MX350F128H-I/MR when your application needs more than 64 KB of Flash or 16 KB of SRAM. The PIC32MX330F064H is sufficient for simple USB device stacks, basic HMI, and small sensor hubs, but tight code fits become challenging for graphics-rich USB composite designs. Since both parts share the 64-pin QFN EP (MR) footprint, you can prototype on the PIC32MX330 and scale to the PIC32MX350 without PCB rework.
What is the best drop-in replacement for PIC32MX350F128H-I/MR?
The best drop-in replacements are PIC32MX450F256H-I/MR and PIC32MX340F128H-80I/MR, both in the same 64-pin QFN EP (MR) footprint. The PIC32MX450 upgrades Flash to 256 KB while remaining pin-compatible, and the PIC32MX340 is a near-identical 80 MHz variant. Cross-brand equivalents like NXP LPC1549 or STM32F105 are NOT drop-in due to differing packages and pinouts.
Where can I download the PIC32MX350F128H datasheet PDF?
The official Microchip PIC32MX350F128H family datasheet is hosted at https://ww1.microchip.com/downloads/en/DeviceDoc/60001185H.pdf as listed in the Microchip product page. The datasheet covers PIC32MX330/350/370/430/450/470 family variants and is approximately 344 pages. Companion documents include the PIC32MX Family Reference Manual sections, MPLAB Harmony documentation, and errata data sheets for each silicon revision.
What is the pinout of PIC32MX350F128H-I/MR in QFN-64?
The PIC32MX350F128H-I/MR uses a 64-pin QFN with dedicated supply pins for VDD/VSS, AVDD/AVSS, and a central exposed thermal pad that must be soldered to the ground plane. Most digital pins are multiplexed via PPS - VBUS/USB D+/D-, I2C1/I2C2 SCL/SDA, SPI/I2S, UART, and the PMP bus each occupy dedicated bond pads. Full pin tables appear in the PIC32MX3/4 datasheet section 39, "I/O Pin Descriptions".
What are the key specifications of PIC32MX350F128H-I/MR that engineers should know?
Key PIC32MX350F128H-I/MR specifications are: 100 MHz MIPS32 M4K core delivering 150 DMIPS, 128 KB Flash, 32 KB SRAM, 53 digital I/O, 2.3 V to 3.6 V supply, USB 2.0 Full-Speed OTG, two I2S/SPI modules, two I2C ports, two analog comparators, a 10-bit 1 Msps ADC with up to 28 channels, Parallel Master Port for graphics, Charge Time Measurement Unit for capacitive touch, and -40C to +105C industrial temperature range in a 64-pin QFN EP (MR) package.

Engineering reference data for PIC32MX350F128H-I/MR — comparison, design guidance, and compliance information.

Selection Guide

Choose the PIC32MX350F128H-I/MR when you need a 100 MHz MIPS32 M4K MCU with USB 2.0 Full-Speed OTG, 128 KB Flash, and 32 KB SRAM in a 64-pin QFN EP package. The part is well matched to USB audio device firmware, capacitive touch HMI panels using the on-chip CTMU, and PMP-driven graphics HMI. If you need more Flash for richer USB stacks or graphics assets, choose the PIC32MX450F256H-I/MR drop-in upgrade (256 KB Flash, Hi-Speed USB). If you need a cost-down option with the same peripherals and can fit 64 KB Flash, choose the PIC32MX330F064H-I/MR. For lower power at 50 MHz with much more memory, evaluate the PIC32MX270F512H-I/MR. Cross-brand alternatives from NXP, ST, or Renesas are NOT drop-in pin-compatible and require PCB redesign plus firmware rewrite.

Comparison with Alternatives

Parameter This Product PIC32MX450F256H-I/MR PIC32MX340F128H-80I/MR PIC32MX330F064H-I/MR PIC32MX340F256HT-80V/MR PIC32MX270F512H-I/MR
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Package QFN-64 EP (MR), 9x9 mm QFN-64 EP (MR) - same QFN-64 EP (MR) - same QFN-64 EP (MR) - same QFN-64 EP (MR) - same QFN-64 EP (MR) - same
Core Architecture MIPS32 M4K MIPS32 M4K MIPS32 M4K MIPS32 M4K MIPS32 M4K MIPS32 M4K
Maximum CPU Speed 100 MHz (150 DMIPS) 100 MHz 80 MHz (-20%) 100 MHz 80 MHz (-20%) 50 MHz (-50%)
Flash Memory 128 KB 256 KB (+100%) 128 KB 64 KB (-50%) 256 KB (+100%) 512 KB (+300%)
SRAM 32 KB 32 KB 32 KB 16 KB (-50%) 32 KB 64 KB (+100%)
USB USB 2.0 Full-Speed OTG USB 2.0 Hi-Speed OTG USB 2.0 Full-Speed OTG USB 2.0 Full-Speed OTG USB 2.0 Full-Speed OTG USB 2.0 Full-Speed OTG
Operating Voltage 2.3 V to 3.6 V 2.3 V to 3.6 V 2.3 V to 3.6 V 2.3 V to 3.6 V 2.3 V to 3.6 V 2.3 V to 3.6 V
Operating Temperature -40C to +105C -40C to +105C -40C to +105C -40C to +105C -40C to +105C -40C to +105C

Key Differentiators

  • Doubled Flash and SRAM versus the PIC32MX330F064H in the same QFN-64 footprint (vs PIC32MX330F064H-I/MR)
  • Industry-standard Peripheral Pin Select (PPS) flexibility (vs PIC32MX340F128H-80I/MR)
  • Higher 100 MHz CPU speed at 128 KB Flash tier (vs PIC32MX270F512H-I/MR)

Design Notes

Place one 0.1uF ceramic decoupling capacitor adjacent to every VDD/AVDD pin pair (the PIC32MX350F128H-I/MR has 3 VDD/VSS pairs plus an AVDD/AVSS pair). Add a bulk 10uF ceramic or tantalum capacitor near the package to handle USB inrush current, since the USB transceiver draws up to 50 mA during enumeration. Tie VBUS through a 5V-tolerant pin to detect USB attachment, and route the internal 3.3V USB regulator output (VBUSON) to a 4.7uF bypass capacitor. AVDD must be at least 3.0 V for accurate ADC readings; use a ferrite bead or separate LDO if analog performance is critical.

Solder the central exposed pad of the QFN-64 (MR) package to a continuous ground pour with multiple stitching vias. The exposed pad carries substantial thermal current and serves as the dominant heat dissipation path. Keep all trace lengths to the 8 MHz crystal or external oscillator short and surrounded by a ground guard ring, and place the crystal load capacitors (typically 22 pF to 33 pF) close to the OSCI/OSCO pins. For USB D+/D- traces, maintain 90-ohm differential impedance and avoid routing near high-frequency switching signals.

Peripheral Pin Select (PPS) allows remapping of most digital peripherals to nearly any I/O pin, but the mapping is locked at runtime by writing to the PPS registers. Document the mapping in firmware with a single source-of-truth table so that PCB schematic labels match the actual pin assignments. Reserve a few spare GPIO pins connected to test pads for in-field debugging and boundary-scan troubleshooting. When using PMP for a TFT LCD, group the data lines D0..D15 together and route them in parallel to maintain signal skew.

Estimated: At 100 MHz with USB active and PMP writes to a TFT, sustained power dissipation can reach 0.5 W. With the QFN-64 EP thermal pad soldered to 1 sq-in of 2-oz copper on a 4-layer FR-4 board, theta_JA is approximately 25 C/W, allowing operation up to +105C ambient. Do not leave the CTMU module unconfigured when unused - leave its corresponding analog pin as digital input with the CTMU disabled, otherwise the input buffer may float and draw extra current. Always set the JTAGEN bit to 0 if JTAG pins are repurposed for general I/O via PPS, to avoid contention with debug probes.

USB D+/D- require 90-ohm differential routing with matching lengths within 2 mm. Place the USB common-mode choke and ESD protection diode within 5 mm of the USB connector, and avoid stubs on the D+/D- lines. For SPI-driven external devices running above 25 MHz, keep clock and data trace lengths matched and add a 22-ohm series resistor at the source end to dampen reflections. The PMP bus should not exceed 25 MHz on the QFN-64 package without a series resistor on the read strobe to limit ringing.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

RoHS and lead-free per Microchip product page. Not AEC-Q100 qualified - automotive applications require PIC32MXxxx-Q1 variants. Industrial -40C to +105C temperature range per the I/MR suffix in the Microchip part numbering convention.

Data verified on: 2026-10-02 — data verified and curated by XAIPART's component engineering team

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